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Items: 1 to 20 of 252

1.

Immune Profiling of Human Gut-Associated Lymphoid Tissue Identifies a Role for Isolated Lymphoid Follicles in Priming of Region-Specific Immunity.

Fenton TM, Jørgensen PB, Niss K, Rubin SJS, Mörbe UM, Riis LB, Da Silva C, Plumb A, Vandamme J, Jakobsen HL, Brunak S, Habtezion A, Nielsen OH, Johansson-Lindbom B, Agace WW.

Immunity. 2020 Mar 17;52(3):557-570.e6. doi: 10.1016/j.immuni.2020.02.001. Epub 2020 Mar 10.

PMID:
32160523
2.

Sex differences in text-mined possible adverse drug events associated with drugs for psychosis.

Sørup FKH, Eriksson R, Westergaard D, Hallas J, Brunak S, Ejdrup Andersen S.

J Psychopharmacol. 2020 Feb 12:269881120903466. doi: 10.1177/0269881120903466. [Epub ahead of print]

PMID:
32048538
3.

Lipidomic profiles, lipid trajectories and clinical biomarkers in female elite endurance athletes.

Varga TV, Ali A, Herrera JAR, Ahonen LL, Mattila IM, Al-Sari NH, Legido-Quigley C, Skouby S, Brunak S, Tornberg ÅB.

Sci Rep. 2020 Feb 11;10(1):2349. doi: 10.1038/s41598-020-59127-8.

4.

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes.

Rheinbay E, Nielsen MM, Abascal F, Wala JA, Shapira O, Tiao G, Hornshøj H, Hess JM, Juul RI, Lin Z, Feuerbach L, Sabarinathan R, Madsen T, Kim J, Mularoni L, Shuai S, Lanzós A, Herrmann C, Maruvka YE, Shen C, Amin SB, Bandopadhayay P, Bertl J, Boroevich KA, Busanovich J, Carlevaro-Fita J, Chakravarty D, Chan CWY, Craft D, Dhingra P, Diamanti K, Fonseca NA, Gonzalez-Perez A, Guo Q, Hamilton MP, Haradhvala NJ, Hong C, Isaev K, Johnson TA, Juul M, Kahles A, Kahraman A, Kim Y, Komorowski J, Kumar K, Kumar S, Lee D, Lehmann KV, Li Y, Liu EM, Lochovsky L, Park K, Pich O, Roberts ND, Saksena G, Schumacher SE, Sidiropoulos N, Sieverling L, Sinnott-Armstrong N, Stewart C, Tamborero D, Tubio JMC, Umer HM, Uusküla-Reimand L, Wadelius C, Wadi L, Yao X, Zhang CZ, Zhang J, Haber JE, Hobolth A, Imielinski M, Kellis M, Lawrence MS, von Mering C, Nakagawa H, Raphael BJ, Rubin MA, Sander C, Stein LD, Stuart JM, Tsunoda T, Wheeler DA, Johnson R, Reimand J, Gerstein M, Khurana E, Campbell PJ, López-Bigas N; PCAWG Drivers and Functional Interpretation Working Group; PCAWG Structural Variation Working Group, Weischenfeldt J, Beroukhim R, Martincorena I, Pedersen JS, Getz G; PCAWG Consortium.

Nature. 2020 Feb;578(7793):102-111. doi: 10.1038/s41586-020-1965-x. Epub 2020 Feb 5.

5.

Pan-cancer analysis of whole genomes.

ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium.

Nature. 2020 Feb;578(7793):82-93. doi: 10.1038/s41586-020-1969-6. Epub 2020 Feb 5.

6.

Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis.

Carlevaro-Fita J, Lanzós A, Feuerbach L, Hong C, Mas-Ponte D, Pedersen JS; PCAWG Drivers and Functional Interpretation Group, Johnson R; PCAWG Consortium.

Commun Biol. 2020 Feb 5;3(1):56. doi: 10.1038/s42003-019-0741-7.

7.

Pathway and network analysis of more than 2500 whole cancer genomes.

Reyna MA, Haan D, Paczkowska M, Verbeke LPC, Vazquez M, Kahraman A, Pulido-Tamayo S, Barenboim J, Wadi L, Dhingra P, Shrestha R, Getz G, Lawrence MS, Pedersen JS, Rubin MA, Wheeler DA, Brunak S, Izarzugaza JMG, Khurana E, Marchal K, von Mering C, Sahinalp SC, Valencia A; PCAWG Drivers and Functional Interpretation Working Group, Reimand J, Stuart JM, Raphael BJ; PCAWG Consortium.

Nat Commun. 2020 Feb 5;11(1):729. doi: 10.1038/s41467-020-14367-0.

8.

Integrative pathway enrichment analysis of multivariate omics data.

Paczkowska M, Barenboim J, Sintupisut N, Fox NS, Zhu H, Abd-Rabbo D, Mee MW, Boutros PC; PCAWG Drivers and Functional Interpretation Working Group, Reimand J; PCAWG Consortium.

Nat Commun. 2020 Feb 5;11(1):735. doi: 10.1038/s41467-019-13983-9.

9.

Combined burden and functional impact tests for cancer driver discovery using DriverPower.

Shuai S; PCAWG Drivers and Functional Interpretation Working Group, Gallinger S, Stein L; PCAWG Consortium.

Nat Commun. 2020 Feb 5;11(1):734. doi: 10.1038/s41467-019-13929-1.

10.

The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study.

Koivula RW, Atabaki-Pasdar N, Giordano GN, White T, Adamski J, Bell JD, Beulens J, Brage S, Brunak S, De Masi F, Dermitzakis ET, Forgie IM, Frost G, Hansen T, Hansen TH, Hattersley A, Kokkola T, Kurbasic A, Laakso M, Mari A, McDonald TJ, Pedersen O, Rutters F, Schwenk JM, Teare HJA, Thomas EL, Vinuela A, Mahajan A, McCarthy MI, Ruetten H, Walker M, Pearson E, Pavo I, Franks PW; IMI DIRECT Consortium.

Diabetologia. 2020 Apr;63(4):744-756. doi: 10.1007/s00125-019-05083-6. Epub 2020 Jan 30.

11.

Linking glycemic dysregulation in diabetes to symptoms, comorbidities, and genetics through EHR data mining.

Kirk IK, Simon C, Banasik K, Holm PC, Haue AD, Jensen PB, Juhl Jensen L, Rodríguez CL, Pedersen MK, Eriksson R, Andersen HU, Almdal T, Bork-Jensen J, Grarup N, Borch-Johnsen K, Pedersen O, Pociot F, Hansen T, Bergholdt R, Rossing P, Brunak S.

Elife. 2019 Dec 10;8. pii: e44941. doi: 10.7554/eLife.44941.

12.

Estimating heritability and genetic correlations from large health datasets in the absence of genetic data.

Jia G, Li Y, Zhang H, Chattopadhyay I, Boeck Jensen A, Blair DR, Davis L, Robinson PN, Dahlén T, Brunak S, Benson M, Edgren G, Cox NJ, Gao X, Rzhetsky A.

Nat Commun. 2019 Dec 3;10(1):5508. doi: 10.1038/s41467-019-13455-0.

13.

Identifying Sepsis Phenotypes.

Moseley PL, Brunak S.

JAMA. 2019 Oct 8;322(14):1416-1417. doi: 10.1001/jama.2019.12591. No abstract available.

PMID:
31593266
14.

Author Correction: Leveraging European infrastructures to access 1 million human genomes by 2022.

Saunders G, Baudis M, Becker R, Beltran S, Béroud C, Birney E, Brooksbank C, Brunak S, Van den Bulcke M, Drysdale R, Capella-Gutierrez S, Flicek P, Florindi F, Goodhand P, Gut I, Heringa J, Holub P, Hooyberghs J, Juty N, Keane TM, Korbel JO, Lappalainen I, Leskosek B, Matthijs G, Mayrhofer MT, Metspalu A, Navarro A, Newhouse S, Nyrönen T, Page A, Persson B, Palotie A, Parkinson H, Rambla J, Salgado D, Steinfelder E, Swertz MA, Valencia A, Varma S, Blomberg N, Scollen S.

Nat Rev Genet. 2019 Nov;20(11):702. doi: 10.1038/s41576-019-0178-3.

PMID:
31520075
15.

Leveraging European infrastructures to access 1 million human genomes by 2022.

Saunders G, Baudis M, Becker R, Beltran S, Béroud C, Birney E, Brooksbank C, Brunak S, Van den Bulcke M, Drysdale R, Capella-Gutierrez S, Flicek P, Florindi F, Goodhand P, Gut I, Heringa J, Holub P, Hooyberghs J, Juty N, Keane TM, Korbel JO, Lappalainen I, Leskosek B, Matthijs G, Mayrhofer MT, Metspalu A, Navarro A, Newhouse S, Nyrönen T, Page A, Persson B, Palotie A, Parkinson H, Rambla J, Salgado D, Steinfelder E, Swertz MA, Valencia A, Varma S, Blomberg N, Scollen S.

Nat Rev Genet. 2019 Nov;20(11):693-701. doi: 10.1038/s41576-019-0156-9. Epub 2019 Aug 27. Review. Erratum in: Nat Rev Genet. 2019 Sep 13;:.

PMID:
31455890
16.

Incorporating symptom data in longitudinal disease trajectories for more detailed patient stratification.

Lademann M, Lademann M, Boeck Jensen A, Brunak S.

Int J Med Inform. 2019 Sep;129:107-113. doi: 10.1016/j.ijmedinf.2019.06.003. Epub 2019 Jun 4.

17.

The bio.tools registry of software tools and data resources for the life sciences.

Ison J, Ienasescu H, Chmura P, Rydza E, Ménager H, Kalaš M, Schwämmle V, Grüning B, Beard N, Lopez R, Duvaud S, Stockinger H, Persson B, Vařeková RS, Raček T, Vondrášek J, Peterson H, Salumets A, Jonassen I, Hooft R, Nyrönen T, Valencia A, Capella S, Gelpí J, Zambelli F, Savakis B, Leskošek B, Rapacki K, Blanchet C, Jimenez R, Oliveira A, Vriend G, Collin O, van Helden J, Løngreen P, Brunak S.

Genome Biol. 2019 Aug 12;20(1):164. doi: 10.1186/s13059-019-1772-6.

18.

Identification of hyper-rewired genomic stress non-oncogene addiction genes across 15 cancer types.

Hjaltelin JX, Izarzugaza JMG, Jensen LJ, Russo F, Westergaard D, Brunak S.

NPJ Syst Biol Appl. 2019 Aug 7;5:27. doi: 10.1038/s41540-019-0104-5. eCollection 2019.

19.

Combined Ensemble Docking and Machine Learning in Identification of Therapeutic Agents with Potential Inhibitory Effect on Human CES1.

Briand E, Thomsen R, Linnet K, Rasmussen HB, Brunak S, Taboureau O.

Molecules. 2019 Jul 29;24(15). pii: E2747. doi: 10.3390/molecules24152747.

20.

sAOP: linking chemical stressors to adverse outcomes pathway networks.

Aguayo-Orozco A, Audouze K, Siggaard T, Barouki R, Brunak S, Taboureau O.

Bioinformatics. 2019 Dec 15;35(24):5391-5392. doi: 10.1093/bioinformatics/btz570.

PMID:
31329252

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