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Items: 9


Lengths of the C-Terminus and Interconnecting Loops Impact Stability of Spider-Derived Gating Modifier Toxins.

Agwa AJ, Huang YH, Craik DJ, Henriques ST, Schroeder CI.

Toxins (Basel). 2017 Aug 12;9(8). pii: E248. doi: 10.3390/toxins9080248.


New Potent Membrane-Targeting Antibacterial Peptides from Viral Capsid Proteins.

Dias SA, Freire JM, Pérez-Peinado C, Domingues MM, Gaspar D, Vale N, Gomes P, Andreu D, Henriques ST, Castanho MARB, Veiga AS.

Front Microbiol. 2017 May 4;8:775. doi: 10.3389/fmicb.2017.00775. eCollection 2017.


Gating modifier toxin interactions with ion channels and lipid bilayers: Is the trimolecular complex real?

Agwa AJ, Henriques ST, Schroeder CI.

Neuropharmacology. 2017 Apr 8. pii: S0028-3908(17)30141-7. doi: 10.1016/j.neuropharm.2017.04.004. [Epub ahead of print] Review.


Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7.

Agwa AJ, Lawrence N, Deplazes E, Cheneval O, Chen RM, Craik DJ, Schroeder CI, Henriques ST.

Biochim Biophys Acta. 2017 May;1859(5):835-844. doi: 10.1016/j.bbamem.2017.01.020. Epub 2017 Jan 20.


Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold.

Huang YH, Henriques ST, Wang CK, Thorstholm L, Daly NL, Kaas Q, Craik DJ.

Sci Rep. 2015 Aug 12;5:12974. doi: 10.1038/srep12974.


Optimization of the cyclotide framework to improve cell penetration properties.

Huang YH, Chaousis S, Cheneval O, Craik DJ, Henriques ST.

Front Pharmacol. 2015 Feb 9;6:17. doi: 10.3389/fphar.2015.00017. eCollection 2015.


Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds.

Chan LY, Gunasekera S, Henriques ST, Worth NF, Le SJ, Clark RJ, Campbell JH, Craik DJ, Daly NL.

Blood. 2011 Dec 15;118(25):6709-17. doi: 10.1182/blood-2011-06-359141. Epub 2011 Oct 28.


Identification and characterization of a new family of cell-penetrating peptides: cyclic cell-penetrating peptides.

Cascales L, Henriques ST, Kerr MC, Huang YH, Sweet MJ, Daly NL, Craik DJ.

J Biol Chem. 2011 Oct 21;286(42):36932-43. doi: 10.1074/jbc.M111.264424. Epub 2011 Aug 26.


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