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Items: 1 to 20 of 86

1.

Anticancer activity and antibody-dependent cell-mediated cytotoxicity of novel anti-nucleolin antibodies.

Romano S, Moura V, Simões S, Moreira JN, Gonçalves J.

Sci Rep. 2018 May 10;8(1):7450. doi: 10.1038/s41598-018-25816-8.

2.

Meeting the needs of breast cancer: A nucleolin's perspective.

Gregório AC, Lacerda M, Figueiredo P, Simões S, Dias S, Moreira JN.

Crit Rev Oncol Hematol. 2018 May;125:89-101. doi: 10.1016/j.critrevonc.2018.03.008. Epub 2018 Mar 21. Review.

PMID:
29650282
3.

Targeting cancer stem cells and non-stem cancer cells: the potential of lipid-based nanoparticles.

Cruz AF, Fonseca NA, Moura V, Simoes S, Moreira JN.

Curr Pharm Des. 2017 Nov 14. doi: 10.2174/1381612823666171115105252. [Epub ahead of print]

PMID:
29141533
4.

Therapeutic Implications of the Molecular and Immune Landscape of Triple-Negative Breast Cancer.

Gregório AC, Lacerda M, Figueiredo P, Simões S, Dias S, Moreira JN.

Pathol Oncol Res. 2018 Oct;24(4):701-716. doi: 10.1007/s12253-017-0307-2. Epub 2017 Sep 14. Review.

PMID:
28913723
5.

Retrospective Quality by Design (rQbD) applied to the optimization of orodispersible films.

Silva BMA, Vicente S, Cunha S, Coelho JFJ, Silva C, Reis MS, Simões S.

Int J Pharm. 2017 Aug 7;528(1-2):655-663. doi: 10.1016/j.ijpharm.2017.06.054. Epub 2017 Jun 17.

PMID:
28629981
6.

Increasing the Bile Acid Sequestration Performance of Cationic Hydrogels by Using an Advanced/Controlled Polymerization Technique.

Mendonça PV, Matos A, Sousa AF, Serra AC, Simões S, Coelho JFJ.

Pharm Res. 2017 Sep;34(9):1934-1943. doi: 10.1007/s11095-017-2204-5. Epub 2017 Jun 16.

PMID:
28623473
7.

The cancer stem cell phenotype as a determinant factor of the heterotypic nature of breast tumors.

Fonseca NA, Cruz AF, Moura V, Simões S, Moreira JN.

Crit Rev Oncol Hematol. 2017 May;113:111-121. doi: 10.1016/j.critrevonc.2017.03.016. Epub 2017 Mar 16. Review.

PMID:
28427501
8.

Myosin II promotes the anisotropic loss of the apical domain during Drosophila neuroblast ingression.

Simões S, Oh Y, Wang MFZ, Fernandez-Gonzalez R, Tepass U.

J Cell Biol. 2017 May 1;216(5):1387-1404. doi: 10.1083/jcb.201608038. Epub 2017 Mar 31.

9.

Integrative Variation Analysis Reveals that a Complex Genotype May Specify Phenotype in Siblings with Syndromic Autism Spectrum Disorder.

Reis VN, Kitajima JP, Tahira AC, Feio-Dos-Santos AC, Fock RA, Lisboa BC, Simões SN, Krepischi AC, Rosenberg C, Lourenço NC, Passos-Bueno MR, Brentani H.

PLoS One. 2017 Jan 24;12(1):e0170386. doi: 10.1371/journal.pone.0170386. eCollection 2017.

10.

Inoculated Cell Density as a Determinant Factor of the Growth Dynamics and Metastatic Efficiency of a Breast Cancer Murine Model.

Gregório AC, Fonseca NA, Moura V, Lacerda M, Figueiredo P, Simões S, Dias S, Moreira JN.

PLoS One. 2016 Nov 7;11(11):e0165817. doi: 10.1371/journal.pone.0165817. eCollection 2016.

11.

Hydrophobic polymers for orodispersible films: a quality by design approach.

Borges AF, Silva BM, Silva C, Coelho JF, Simões S.

Expert Opin Drug Deliv. 2016 Oct;13(10):1357-74. doi: 10.1080/17425247.2016.1218458. Epub 2016 Aug 9.

PMID:
27466880
12.

Outlining critical quality attributes (CQAs) as guidance for the development of orodispersible films.

Borges AF, Silva C, Coelho JF, Simões S.

Pharm Dev Technol. 2017 Mar;22(2):237-245. doi: 10.1080/10837450.2016.1199567. Epub 2016 Jun 27.

PMID:
27346557
13.

Corrigendum: An integrative approach to investigate the respective roles of single-nucleotide variants and copy-number variants in Attention-Deficit/Hyperactivity Disorder.

Lima Lde A, Feio-Dos-Santos AC, Belangero SI, Gadelha A, Bressan RA, Salum GA, Pan PM, Moriyama TS, Graeff-Martins AS, Tamanaha AC, Alvarenga P, Krieger FV, Fleitlich-Bilyk B, Jackowski AP, Brietzke E, Sato JR, Polanczyk GV, Mari Jde J, Manfro GG, do Rosário MC, Miguel EC, Puga RD, Tahira AC, Souza VN, Chile T, Gouveia GR, Simões SN, Chang X, Pellegrino R, Tian L, Glessner JT, Hashimoto RF, Rohde LA, Sleiman PM, Hakonarson H, Brentani H.

Sci Rep. 2016 May 24;6:25861. doi: 10.1038/srep25861. No abstract available.

14.

An integrative approach to investigate the respective roles of single-nucleotide variants and copy-number variants in Attention-Deficit/Hyperactivity Disorder.

Lima Lde A, Feio-dos-Santos AC, Belangero SI, Gadelha A, Bressan RA, Salum GA, Pan PM, Moriyama TS, Graeff-Martins AS, Tamanaha AC, Alvarenga P, Krieger FV, Fleitlich-Bilyk B, Jackowski AP, Brietzke E, Sato JR, Polanczyk GV, Mari Jde J, Manfro GG, do Rosário MC, Miguel EC, Puga RD, Tahira AC, Souza VN, Chile T, Gouveia GR, Simões SN, Chang X, Pellegrino R, Tian L, Glessner JT, Hashimoto RF, Rohde LA, Sleiman PM, Hakonarson H, Brentani H.

Sci Rep. 2016 Mar 7;6:22851. doi: 10.1038/srep22851. Erratum in: Sci Rep. 2016 May 24;6:25861.

15.

Muscle versus Snail: Muscle wins.

Simoes S, Tepass U.

J Cell Biol. 2016 Jan 18;212(2):139-41. doi: 10.1083/jcb.201512092. Epub 2016 Jan 11.

16.

NERI: network-medicine based integrative approach for disease gene prioritization by relative importance.

Simões SN, Martins DC Jr, Pereira CA, Hashimoto RF, Brentani H.

BMC Bioinformatics. 2015;16 Suppl 19:S9. doi: 10.1186/1471-2105-16-S19-S9. Epub 2015 Dec 16.

17.

Intravenous Single-Dose Toxicity of Redaporfin-Based Photodynamic Therapy in Rodents.

Rocha LB, Schaberle F, Dąbrowski JM, Simões S, Arnaut LG.

Int J Mol Sci. 2015 Dec 8;16(12):29236-49. doi: 10.3390/ijms161226162.

18.

Mucoadhesive oral films: The potential for unmet needs.

Silva BM, Borges AF, Silva C, Coelho JF, Simões S.

Int J Pharm. 2015 Oct 15;494(1):537-51. doi: 10.1016/j.ijpharm.2015.08.038. Epub 2015 Aug 24. Review.

PMID:
26315122
19.

Nucleolin overexpression in breast cancer cell sub-populations with different stem-like phenotype enables targeted intracellular delivery of synergistic drug combination.

Fonseca NA, Rodrigues AS, Rodrigues-Santos P, Alves V, Gregório AC, Valério-Fernandes Â, Gomes-da-Silva LC, Rosa MS, Moura V, Ramalho-Santos J, Simões S, Moreira JN.

Biomaterials. 2015 Nov;69:76-88. doi: 10.1016/j.biomaterials.2015.08.007. Epub 2015 Aug 6.

PMID:
26283155
20.

Oral films: Current status and future perspectives II - Intellectual property, technologies and market needs.

Borges AF, Silva C, Coelho JF, Simões S.

J Control Release. 2015 May 28;206:108-21. doi: 10.1016/j.jconrel.2015.03.012. Epub 2015 Mar 14. Review. No abstract available.

PMID:
25776737

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