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Items: 1 to 20 of 22

1.

Antileukemic Activity of Twig Components of Caucasian Beech in Turkey.

Shida W, Tateishi H, Tahara Y, Fujita M, Husham Majeed Alsaadi D, Watanabe M, Koga R, Radwan MO, Ciftci HI, Gezici S, Kurauchi Y, Katsuki H, Otsuka M, Sugimura K, Wada M, Sekeroglu N, Watanabe T.

Molecules. 2019 Oct 25;24(21). pii: E3850. doi: 10.3390/molecules24213850.

2.

Anti-cancer activity of the cell membrane-permeable phytic acid prodrug.

Masunaga T, Murao N, Tateishi H, Koga R, Ohsugi T, Otsuka M, Fujita M.

Bioorg Chem. 2019 Nov;92:103240. doi: 10.1016/j.bioorg.2019.103240. Epub 2019 Sep 4.

PMID:
31525525
3.

Antiproliferative S-Trityl-l-Cysteine -Derived Compounds as SIRT2 Inhibitors: Repurposing and Solubility Enhancement.

Radwan MO, Ciftci HI, Ali TFS, Ellakwa DE, Koga R, Tateishi H, Nakata A, Ito A, Yoshida M, Okamoto Y, Fujita M, Otsuka M.

Molecules. 2019 Sep 10;24(18). pii: E3295. doi: 10.3390/molecules24183295.

4.

Minimum structural requirements for inhibitors of the zinc finger protein TRAF6.

Radwan MO, Koga R, Hida T, Ejima T, Kanemaru Y, Tateishi H, Okamoto Y, Inoue JI, Fujita M, Otsuka M.

Bioorg Med Chem Lett. 2019 Aug 15;29(16):2162-2167. doi: 10.1016/j.bmcl.2019.06.050. Epub 2019 Jun 27.

PMID:
31272791
5.

Serial Femtosecond X-Ray Diffraction of HIV-1 Gag MA-IP6 Microcrystals at Ambient Temperature.

I Ciftci H, G Sierra R, Yoon CH, Su Z, Tateishi H, Koga R, Kotaro K, Yumoto F, Senda T, Liang M, Wakatsuki S, Otsuka M, Fujita M, DeMirci H.

Int J Mol Sci. 2019 Apr 3;20(7). pii: E1675. doi: 10.3390/ijms20071675.

6.

New SIRT2 inhibitors: Histidine-based bleomycin spin-off.

Ali TFS, Ciftci HI, Radwan MO, Koga R, Ohsugi T, Okiyama Y, Honma T, Nakata A, Ito A, Yoshida M, Fujita M, Otsuka M.

Bioorg Med Chem. 2019 May 1;27(9):1767-1775. doi: 10.1016/j.bmc.2019.03.003. Epub 2019 Mar 2.

PMID:
30885568
7.

Neuroprotective effects of a novel carnosine-hydrazide derivative on hippocampal CA1 damage after transient cerebral ischemia.

Noguchi K, Ali TFS, Miyoshi J, Orito K, Negoto T, Biswas T, Taira N, Koga R, Okamoto Y, Fujita M, Otsuka M, Morioka M.

Eur J Med Chem. 2019 Feb 1;163:207-214. doi: 10.1016/j.ejmech.2018.11.060. Epub 2018 Nov 28.

8.

The First Pentacyclic Triterpenoid Gypsogenin Derivative Exhibiting Anti-ABL1 Kinase and Anti-chronic Myelogenous Leukemia Activities.

Ciftci HI, Ozturk SE, Ali TFS, Radwan MO, Tateishi H, Koga R, Ocak Z, Can M, Otsuka M, Fujita M.

Biol Pharm Bull. 2018 Apr 1;41(4):570-574. doi: 10.1248/bpb.b17-00902. Epub 2018 Jan 30.

9.

Introduction of H2C2-type zinc-binding residues into HIV-2 Vpr increases its expression level.

Koga R, Yamamoto M, Ciftci HI, Otsuka M, Fujita M.

FEBS Open Bio. 2017 Dec 19;8(1):146-153. doi: 10.1002/2211-5463.12358. eCollection 2018 Jan.

10.

Design, Synthesis, and Biological Evaluation of Novel 1,3,4-Thiadiazole Derivatives as Potential Antitumor Agents against Chronic Myelogenous Leukemia: Striking Effect of Nitrothiazole Moiety.

Altıntop MD, Ciftci HI, Radwan MO, Sever B, Kaplancıklı ZA, Ali TFS, Koga R, Fujita M, Otsuka M, Özdemir A.

Molecules. 2017 Dec 27;23(1). pii: E59. doi: 10.3390/molecules23010059.

11.

A Dithiol Compound Binds to the Zinc Finger Protein TRAF6 and Suppresses Its Ubiquitination.

Koga R, Radwan MO, Ejima T, Kanemaru Y, Tateishi H, Ali TFS, Ciftci HI, Shibata Y, Taguchi Y, Inoue JI, Otsuka M, Fujita M.

ChemMedChem. 2017 Dec 7;12(23):1935-1941. doi: 10.1002/cmdc.201700399. Epub 2017 Oct 4.

PMID:
28884970
12.

A clue to unprecedented strategy to HIV eradication: "Lock-in and apoptosis".

Tateishi H, Monde K, Anraku K, Koga R, Hayashi Y, Ciftci HI, DeMirci H, Higashi T, Motoyama K, Arima H, Otsuka M, Fujita M.

Sci Rep. 2017 Aug 21;7(1):8957. doi: 10.1038/s41598-017-09129-w.

13.

A novel inhibitor of farnesyltransferase with a zinc site recognition moiety and a farnesyl group.

Tanaka A, Radwan MO, Hamasaki A, Ejima A, Obata E, Koga R, Tateishi H, Okamoto Y, Fujita M, Nakao M, Umezawa K, Tamanoi F, Otsuka M.

Bioorg Med Chem Lett. 2017 Aug 15;27(16):3862-3866. doi: 10.1016/j.bmcl.2017.06.047. Epub 2017 Jun 20.

PMID:
28666734
14.

Zinc-binding site of human immunodeficiency virus 2 Vpx prevents instability and dysfunction of the protein.

Yamamoto M, Koga R, Fujino H, Shimagaki K, Ciftci HI, Kamo M, Tateishi H, Otsuka M, Fujita M.

J Gen Virol. 2017 Feb;98(2):275-283. doi: 10.1099/jgv.0.000701.

PMID:
28284276
15.

Zinc-mediated binding of a low-molecular-weight stabilizer of the host anti-viral factor apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G.

Radwan MO, Sonoda S, Ejima T, Tanaka A, Koga R, Okamoto Y, Fujita M, Otsuka M.

Bioorg Med Chem. 2016 Sep 15;24(18):4398-4405. doi: 10.1016/j.bmc.2016.07.030. Epub 2016 Jul 18.

PMID:
27475536
16.

Synthesis of the biotinylated anti-HIV compound BMMP and the target identification study.

Kamo M, Tateishi H, Koga R, Okamoto Y, Otsuka M, Fujita M.

Bioorg Med Chem Lett. 2016 Jan 1;26(1):43-5. doi: 10.1016/j.bmcl.2015.11.036. Epub 2015 Nov 12.

PMID:
26615887
17.

Synthesis and Evaluation of New Pyrazoline Derivatives as Potential Anticancer Agents.

Karabacak M, Altıntop MD, İbrahim Çiftçi H, Koga R, Otsuka M, Fujita M, Özdemir A.

Molecules. 2015 Oct 20;20(10):19066-84. doi: 10.3390/molecules201019066.

18.

Novel metal chelating molecules with anticancer activity. Striking effect of the imidazole substitution of the histidine-pyridine-histidine system.

Ali TF, Iwamaru K, Ciftci HI, Koga R, Matsumoto M, Oba Y, Kurosaki H, Fujita M, Okamoto Y, Umezawa K, Nakao M, Hide T, Makino K, Kuratsu J, Abdel-Aziz M, Abuo-Rahma Gel-D, Beshr EA, Otsuka M.

Bioorg Med Chem. 2015 Sep 1;23(17):5476-82. doi: 10.1016/j.bmc.2015.07.044. Epub 2015 Jul 29.

PMID:
26260338
19.

Mutational analysis of HIV-2 Vpx shows that proline residue 109 in the poly-proline motif regulates degradation of SAMHD1.

Ciftci HI, Fujino H, Koga R, Yamamoto M, Kawamura S, Tateishi H, Iwatani Y, Otsuka M, Fujita M.

FEBS Lett. 2015 Jun 4;589(13):1505-14. doi: 10.1016/j.febslet.2015.04.038. Epub 2015 Apr 30.

20.

Design and synthesis of lipid-coupled inositol 1,2,3,4,5,6-hexakisphosphate derivatives exhibiting high-affinity binding for the HIV-1 MA domain.

Tateishi H, Anraku K, Koga R, Okamoto Y, Fujita M, Otsuka M.

Org Biomol Chem. 2014 Jul 21;12(27):5006-22. doi: 10.1039/c4ob00350k.

PMID:
24887478

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