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Items: 1 to 20 of 42

1.

A comparison of prostate cancer cell transcriptomes in 2D monoculture vs 3D xenografts identify consistent gene expression alterations associated with tumor microenvironments.

Brady L, Gil da Costa RM, Coleman IM, Matson CK, Risk MC, Coleman RT, Nelson PS.

Prostate. 2020 Feb 18. doi: 10.1002/pros.23963. [Epub ahead of print]

PMID:
32068909
2.

HPV16 is sufficient to induce squamous cell carcinoma specifically in the tongue base in transgenic mice.

Mestre VF, Medeiros-Fonseca B, Estêvão D, Casaca F, Silva S, Félix A, Silva F, Colaço B, Seixas F, Bastos MMSM, Lopes C, Medeiros R, Oliveira PA, Gil da Costa RM.

J Pathol. 2020 Jan 28. doi: 10.1002/path.5387. [Epub ahead of print]

PMID:
31994197
3.

Dietary Supplementation with the Red Seaweed Porphyra umbilicalis Protects against DNA Damage and Pre-Malignant Dysplastic Skin Lesions in HPV-Transgenic Mice.

Santos S, Ferreira T, Almeida J, Pires MJ, Colaço A, Lemos S, Gil da Costa RM, Medeiros R, Bastos MMSM, Neuparth MJ, Abreu H, Pereira R, Pacheco M, Gaivão I, Rosa E, Oliveira PA.

Mar Drugs. 2019 Oct 29;17(11). pii: E615. doi: 10.3390/md17110615.

4.

Testosterone accumulation in prostate cancer cells is enhanced by facilitated diffusion.

Kaipainen A, Zhang A, Gil da Costa RM, Lucas J, Marck B, Matsumoto AM, Morrissey C, True LD, Mostaghel EA, Nelson PS.

Prostate. 2019 Sep;79(13):1530-1542. doi: 10.1002/pros.23874. Epub 2019 Aug 2.

PMID:
31376206
5.

Molecular profiling stratifies diverse phenotypes of treatment-refractory metastatic castration-resistant prostate cancer.

Labrecque MP, Coleman IM, Brown LG, True LD, Kollath L, Lakely B, Nguyen HM, Yang YC, da Costa RMG, Kaipainen A, Coleman R, Higano CS, Yu EY, Cheng HH, Mostaghel EA, Montgomery B, Schweizer MT, Hsieh AC, Lin DW, Corey E, Nelson PS, Morrissey C.

J Clin Invest. 2019 Jul 30;130:4492-4505. doi: 10.1172/JCI128212.

6.

Dimethylaminoparthenolide reduces the incidence of dysplasia and ameliorates a wasting syndrome in HPV16-transgenic mice.

Santos JMO, Moreira-Pais A, Neto T, Peixoto da Silva S, Oliveira PA, Ferreira R, Mendes J, Bastos MMSM, Lopes C, Casaca F, Silva S, Sweeney C, Medeiros R, Gil da Costa RM.

Drug Dev Res. 2019 Sep;80(6):824-830. doi: 10.1002/ddr.21565. Epub 2019 Jul 13.

PMID:
31301186
7.

Inhalation of Bacterial Cellulose Nanofibrils Triggers an Inflammatory Response and Changes Lung Tissue Morphology of Mice.

Silva-Carvalho R, Silva JP, Ferreirinha P, Leitão AF, Andrade FK, Gil da Costa RM, Cristelo C, Rosa MF, Vilanova M, Gama FM.

Toxicol Res. 2019 Jan;35(1):45-63. doi: 10.5487/TR.2019.35.1.045. Epub 2018 Jan 15.

8.

Hallmarks of HPV carcinogenesis: The role of E6, E7 and E5 oncoproteins in cellular malignancy.

Estêvão D, Costa NR, Gil da Costa RM, Medeiros R.

Biochim Biophys Acta Gene Regul Mech. 2019 Feb;1862(2):153-162. doi: 10.1016/j.bbagrm.2019.01.001. Epub 2019 Jan 29. Review.

PMID:
30707946
9.

The Role of MicroRNAs in the Metastatic Process of High-Risk HPV-Induced Cancers.

Santos JMO, Peixoto da Silva S, Costa NR, Gil da Costa RM, Medeiros R.

Cancers (Basel). 2018 Dec 5;10(12). pii: E493. doi: 10.3390/cancers10120493. Review.

10.

The Aged Microenvironment Influences the Tumorigenic Potential of Malignant Prostate Epithelial Cells.

Bianchi-Frias D, Damodarasamy M, Hernandez SA, Gil da Costa RM, Vakar-Lopez F, Coleman IM, Reed MJ, Nelson PS.

Mol Cancer Res. 2019 Jan;17(1):321-331. doi: 10.1158/1541-7786.MCR-18-0522. Epub 2018 Sep 17.

11.

Curcumin and Rutin Down-regulate Cyclooxygenase-2 and Reduce Tumor-associated Inflammation in HPV16-Transgenic Mice.

Moutinho MSS, Aragão S, Carmo D, Casaca F, Silva S, Ribeiro J, Sousa H, Pires I, Queiroga F, Colaço B, Medeiros R, Oliveira PA, Lopes C, Bastos MMSM, DA Costa RMG.

Anticancer Res. 2018 Mar;38(3):1461-1466.

PMID:
29491072
12.

A viral map of gastrointestinal cancers.

Costa NR, Gil da Costa RM, Medeiros R.

Life Sci. 2018 Apr 15;199:188-200. doi: 10.1016/j.lfs.2018.02.025. Epub 2018 Feb 21. Review.

PMID:
29476768
13.

Dysregulation of cellular microRNAs by human oncogenic viruses - Implications for tumorigenesis.

Santos JMO, Gil da Costa RM, Medeiros R.

Biochim Biophys Acta Gene Regul Mech. 2018 Feb;1861(2):95-105. doi: 10.1016/j.bbagrm.2018.01.017. Epub 2018 Jan 31. Review.

PMID:
29378330
14.

Carcinocythemia: First report in a cat and literature review.

Sá E Lemos E, Lima de Carvalho H, Gil da Costa RM, Pinto da Cunha N.

Vet Clin Pathol. 2018 Mar;47(1):142-145. doi: 10.1111/vcp.12565. Epub 2018 Jan 23. Review.

PMID:
29360147
15.

Expression profile of microRNA-146a along HPV-induced multistep carcinogenesis: a study in HPV16 transgenic mice.

Araújo R, Santos JMO, Fernandes M, Dias F, Sousa H, Ribeiro J, Bastos MMSM, Oliveira PA, Carmo D, Casaca F, Silva S, Medeiros R, Gil da Costa RM.

J Cancer Res Clin Oncol. 2018 Feb;144(2):241-248. doi: 10.1007/s00432-017-2549-5. Epub 2017 Nov 27.

PMID:
29181576
16.

The N-butyl-N-4-hydroxybutyl Nitrosamine Mouse Urinary Bladder Cancer Model.

Oliveira PA, Vasconcelos-Nóbrega C, Gil da Costa RM, Arantes-Rodrigues R.

Methods Mol Biol. 2018;1655:155-167. doi: 10.1007/978-1-4939-7234-0_13. Review.

PMID:
28889385
17.

Effects of exercise training on breast cancer metastasis in a rat model.

Alvarado A, Gil da Costa RM, Faustino-Rocha AI, Ferreira R, Lopes C, Oliveira PA, Colaço B.

Int J Exp Pathol. 2017 Feb;98(1):40-46. doi: 10.1111/iep.12225.

18.

Regulation of miRNA-146a and miRNA-150 Levels by Celecoxib in Premalignant Lesions of K14-HPV16 Mice.

DA Costa RMG, Araújo R, Santos JMO, Fernandes M, Neto T, Sousa H, Ribeiro J, Bastos MMSM, Oliveira PA, Carmo D, Casaca F, Silva S, Lopes C, Medeiros R.

Anticancer Res. 2017 Jun;37(6):2913-2918.

PMID:
28551628
19.

HPV-transgenic mouse models: Tools for studying the cancer-associated immune response.

Santos C, Vilanova M, Medeiros R, Gil da Costa RM.

Virus Res. 2017 May 2;235:49-57. doi: 10.1016/j.virusres.2017.04.001. Epub 2017 Apr 3. Review.

PMID:
28385491
20.

Dysregulated expression of microRNA-150 in human papillomavirus-induced lesions of K14-HPV16 transgenic mice.

Santos JMO, Fernandes M, Araújo R, Sousa H, Ribeiro J, Bastos MMSM, Oliveira PA, Carmo D, Casaca F, Silva S, Teixeira AL, Gil da Costa RM, Medeiros R.

Life Sci. 2017 Apr 15;175:31-36. doi: 10.1016/j.lfs.2017.03.008. Epub 2017 Mar 14.

PMID:
28302562

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