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Items: 1 to 20 of 69

1.

Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error.

Fan Q, Pozarickij A, Tan NYQ, Guo X, Verhoeven VJM, Vitart V, Guggenheim JA, Miyake M, Tideman JWL, Khawaja AP, Zhang L, MacGregor S, Höhn R, Chen P, Biino G, Wedenoja J, Saffari SE, Tedja MS, Xie J, Lanca C, Wang YX, Sahebjada S, Mazur J, Mirshahi A, Martin NG, Yazar S, Pennell CE, Yap M, Haarman AEG, Enthoven CA, Polling J; Consortium for Refractive Error and Myopia (CREAM); UK Biobank Eye and Vision Consortium, Hewitt AW, Jaddoe VWV, van Duijn CM, Hayward C, Polasek O, Tai ES, Yoshikatsu H, Hysi PG, Young TL, Tsujikawa A, Wang JJ, Mitchell P, Pfeiffer N, Pärssinen O, Foster PJ, Fossarello M, Yip SP, Williams C, Hammond CJ, Jonas JB, He M, Mackey DA, Wong TY, Klaver CCW, Saw SM, Baird PN, Cheng CY.

Commun Biol. 2020 Mar 19;3(1):133. doi: 10.1038/s42003-020-0802-y.

2.

UK consensus on pre-clinical vascular cognitive impairment functional outcomes assessment: questionnaire and workshop proceedings.

McFall A, Hietamies TM, Bernard A, Aimable M, Allan SM, Bath PM, Brezzo G, Carare RO, Carswell HV, Clarkson AN, Currie G, Farr TD, Fowler JH, Good M, Hainsworth AH, Hall C, Horsburgh K, Kalaria R, Kehoe P, Lawrence C, Macleod M, McColl BW, McNeilly A, Miller AA, Miners S, Mok V, O'Sullivan M, Platt B, Sena ES, Sharp M, Strangeward P, Szymkowiak S, Touyz RM, Trueman RC, White C, McCabe C, Work LM, Quinn TJ.

J Cereb Blood Flow Metab. 2020 Mar 9:271678X20910552. doi: 10.1177/0271678X20910552. [Epub ahead of print] No abstract available.

PMID:
32151228
3.

Vital Functions Contribute to the Spread of Extracellular Fluids in the Brain: Comparison Between Life and Death.

Piotrowska A, Winter K, Carare RO, Bechmann I.

Front Aging Neurosci. 2020 Feb 11;12:15. doi: 10.3389/fnagi.2020.00015. eCollection 2020.

4.

The Pattern of AQP4 Expression in the Ageing Human Brain and in Cerebral Amyloid Angiopathy.

Owasil R, O'Neill R, Keable A, Nimmo J, MacGregor Sharp M, Kelly L, Saito S, Simpson JE, Weller RO, Smith C, Attems J, Wharton SB, Yuen HM, Carare RO.

Int J Mol Sci. 2020 Feb 12;21(4). pii: E1225. doi: 10.3390/ijms21041225.

5.

Vasomotion Drives Periarterial Drainage of Aβ from the Brain.

Carare RO, Aldea R, Bulters D, Alzetani A, Birch AA, Richardson G, Weller RO.

Neuron. 2020 Feb 5;105(3):400-401. doi: 10.1016/j.neuron.2020.01.011.

PMID:
32027828
6.

The Diverse Roles of TIMP-3: Insights into Degenerative Diseases of the Senescent Retina and Brain.

Dewing JM, Carare RO, Lotery AJ, Ratnayaka JA.

Cells. 2019 Dec 21;9(1). pii: E39. doi: 10.3390/cells9010039. Review.

7.

Multi-trait genome-wide association study identifies new loci associated with optic disc parameters.

Bonnemaijer PWM, Leeuwen EMV, Iglesias AI, Gharahkhani P, Vitart V, Khawaja AP, Simcoe M, Höhn R, Cree AJ, Igo RP; International Glaucoma Genetics Consortium; NEIGHBORHOOD consortium; UK Biobank Eye and Vision Consortium, Gerhold-Ay A, Nickels S, Wilson JF, Hayward C, Boutin TS, Polašek O, Aung T, Khor CC, Amin N, Lotery AJ, Wiggs JL, Cheng CY, Hysi PG, Hammond CJ, Thiadens AAHJ, MacGregor S, Klaver CCW, Duijn CMV.

Commun Biol. 2019 Nov 27;2:435. doi: 10.1038/s42003-019-0634-9. eCollection 2019.

8.

Solving an Old Dogma: Is it an Arteriole or a Venule?

MacGregor Sharp M, Criswell TP, Dobson H, Finucane C, Verma A, Carare RO.

Front Aging Neurosci. 2019 Oct 22;11:289. doi: 10.3389/fnagi.2019.00289. eCollection 2019.

9.

Brain pharmacology of intrathecal antisense oligonucleotides revealed through multimodal imaging.

Mazur C, Powers B, Zasadny K, Sullivan JM, Dimant H, Kamme F, Hesterman J, Matson J, Oestergaard M, Seaman M, Holt RW, Qutaish M, Polyak I, Coelho R, Gottumukkala V, Gaut CM, Berridge M, Albargothy NJ, Kelly L, Carare RO, Hoppin J, Kordasiewicz H, Swayze EE, Verma A.

JCI Insight. 2019 Oct 17;4(20). pii: 129240. doi: 10.1172/jci.insight.129240.

10.

Comparison of Associations with Different Macular Inner Retinal Thickness Parameters in a Large Cohort: The UK Biobank.

Khawaja AP, Chua S, Hysi PG, Georgoulas S, Currant H, Fitzgerald TW, Birney E, Ko F, Yang Q, Reisman C, Garway-Heath DF, Hammond CJ, Khaw PT, Foster PJ, Patel PJ, Strouthidis N; UK Biobank Eye and Vision Consortium.

Ophthalmology. 2020 Jan;127(1):62-71. doi: 10.1016/j.ophtha.2019.08.015. Epub 2019 Aug 21.

PMID:
31585827
11.

Associations with Corneal Hysteresis in a Population Cohort: Results from 96 010 UK Biobank Participants.

Zhang B, Shweikh Y, Khawaja AP, Gallacher J, Bauermeister S, Foster PJ; UKBiobank Eye and Vision Consortium.

Ophthalmology. 2019 Nov;126(11):1500-1510. doi: 10.1016/j.ophtha.2019.06.029. Epub 2019 Jul 5.

PMID:
31471087
12.

Small vessel disease pathological changes in neurodegenerative and vascular dementias concomitant with autonomic dysfunction.

Hase Y, Polvikoski TM, Firbank MJ, Craggs LJL, Hawthorne E, Platten C, Stevenson W, Deramecourt V, Ballard C, Kenny RA, Perry RH, Ince P, Carare RO, Allan LM, Horsburgh K, Kalaria RN.

Brain Pathol. 2020 Jan;30(1):191-202. doi: 10.1111/bpa.12769. Epub 2019 Aug 16.

PMID:
31357238
13.

3D Reconstruction of the Neurovascular Unit Reveals Differential Loss of Cholinergic Innervation in the Cortex and Hippocampus of the Adult Mouse Brain.

Nizari S, Carare RO, Romero IA, Hawkes CA.

Front Aging Neurosci. 2019 Jul 4;11:172. doi: 10.3389/fnagi.2019.00172. eCollection 2019.

14.

Quantile regression analysis reveals widespread evidence for gene-environment or gene-gene interactions in myopia development.

Pozarickij A, Williams C, Hysi PG, Guggenheim JA; UK Biobank Eye and Vision Consortium.

Commun Biol. 2019 May 6;2:167. doi: 10.1038/s42003-019-0387-5. eCollection 2019.

15.
16.

Cohort profile: design and methods in the eye and vision consortium of UK Biobank.

Chua SYL, Thomas D, Allen N, Lotery A, Desai P, Patel P, Muthy Z, Sudlow C, Peto T, Khaw PT, Foster PJ; UK Biobank Eye & Vision Consortium.

BMJ Open. 2019 Feb 21;9(2):e025077. doi: 10.1136/bmjopen-2018-025077.

17.

Cerebrovascular Smooth Muscle Cells as the Drivers of Intramural Periarterial Drainage of the Brain.

Aldea R, Weller RO, Wilcock DM, Carare RO, Richardson G.

Front Aging Neurosci. 2019 Jan 23;11:1. doi: 10.3389/fnagi.2019.00001. eCollection 2019.

18.

Vascular dysfunction-The disregarded partner of Alzheimer's disease.

Sweeney MD, Montagne A, Sagare AP, Nation DA, Schneider LS, Chui HC, Harrington MG, Pa J, Law M, Wang DJJ, Jacobs RE, Doubal FN, Ramirez J, Black SE, Nedergaard M, Benveniste H, Dichgans M, Iadecola C, Love S, Bath PM, Markus HS, Salman RA, Allan SM, Quinn TJ, Kalaria RN, Werring DJ, Carare RO, Touyz RM, Williams SCR, Moskowitz MA, Katusic ZS, Lutz SE, Lazarov O, Minshall RD, Rehman J, Davis TP, Wellington CL, González HM, Yuan C, Lockhart SN, Hughes TM, Chen CLH, Sachdev P, O'Brien JT, Skoog I, Pantoni L, Gustafson DR, Biessels GJ, Wallin A, Smith EE, Mok V, Wong A, Passmore P, Barkof F, Muller M, Breteler MMB, Román GC, Hamel E, Seshadri S, Gottesman RF, van Buchem MA, Arvanitakis Z, Schneider JA, Drewes LR, Hachinski V, Finch CE, Toga AW, Wardlaw JM, Zlokovic BV.

Alzheimers Dement. 2019 Jan;15(1):158-167. doi: 10.1016/j.jalz.2018.07.222.

19.

CSF Neurofilament Light Chain Levels in Primary Progressive MS: Signs of Axonal Neurodegeneration.

Pawlitzki M, Schreiber S, Bittner D, Kreipe J, Leypoldt F, Rupprecht K, Carare RO, Meuth SG, Vielhaber S, Körtvélyessy P.

Front Neurol. 2018 Dec 14;9:1037. doi: 10.3389/fneur.2018.01037. eCollection 2018.

20.

Military-related risk factors for dementia.

Snyder HM, Carare RO, DeKosky ST, de Leon MJ, Dykxhoorn D, Gan L, Gardner R, Hinds SR 2nd, Jaffee M, Lamb BT, Landau S, Manley G, McKee A, Perl D, Schneider JA, Weiner M, Wellington C, Yaffe K, Bain L, Pacifico AM, Carrillo MC.

Alzheimers Dement. 2018 Dec;14(12):1651-1662. doi: 10.1016/j.jalz.2018.08.011. Epub 2018 Nov 8. Review.

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