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Items: 17

1.

Effects of Aging and Methionine Restriction on Rat Kidney Metabolome.

Pradas I, Jové M, Cabré R, Ayala V, Mota-Martorell N, Pamplona R.

Metabolites. 2019 Nov 14;9(11). pii: E280. doi: 10.3390/metabo9110280.

2.

Lipidomics Reveals a Tissue-Specific Fingerprint.

Pradas I, Huynh K, Cabré R, Ayala V, Meikle PJ, Jové M, Pamplona R.

Front Physiol. 2018 Aug 28;9:1165. doi: 10.3389/fphys.2018.01165. eCollection 2018.

3.

Lipid Profile in Human Frontal Cortex Is Sustained Throughout Healthy Adult Life Span to Decay at Advanced Ages.

Cabré R, Naudí A, Dominguez-Gonzalez M, Jové M, Ayala V, Mota-Martorell N, Pradas I, Nogueras L, Rué M, Portero-Otín M, Ferrer I, Pamplona R.

J Gerontol A Biol Sci Med Sci. 2018 May 9;73(6):703-710. doi: 10.1093/gerona/glx164.

4.

Region-specific vulnerability to lipid peroxidation and evidence of neuronal mechanisms for polyunsaturated fatty acid biosynthesis in the healthy adult human central nervous system.

Naudí A, Cabré R, Dominguez-Gonzalez M, Ayala V, Jové M, Mota-Martorell N, Piñol-Ripoll G, Gil-Villar MP, Rué M, Portero-Otín M, Ferrer I, Pamplona R.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 May;1862(5):485-495. doi: 10.1016/j.bbalip.2017.02.001. Epub 2017 Feb 7.

PMID:
28185952
5.

Specific Metabolomics Adaptations Define a Differential Regional Vulnerability in the Adult Human Cerebral Cortex.

Cabré R, Jové M, Naudí A, Ayala V, Piñol-Ripoll G, Gil-Villar MP, Dominguez-Gonzalez M, Obis È, Berdun R, Mota-Martorell N, Portero-Otin M, Ferrer I, Pamplona R.

Front Mol Neurosci. 2016 Dec 8;9:138. doi: 10.3389/fnmol.2016.00138. eCollection 2016.

6.

Sixty years old is the breakpoint of human frontal cortex aging.

Cabré R, Naudí A, Dominguez-Gonzalez M, Ayala V, Jové M, Mota-Martorell N, Piñol-Ripoll G, Gil-Villar MP, Rué M, Portero-Otín M, Ferrer I, Pamplona R.

Free Radic Biol Med. 2017 Feb;103:14-22. doi: 10.1016/j.freeradbiomed.2016.12.010. Epub 2016 Dec 13.

7.

A Stress-Resistant Lipidomic Signature Confers Extreme Longevity to Humans.

Jové M, Naudí A, Gambini J, Borras C, Cabré R, Portero-Otín M, Viña J, Pamplona R.

J Gerontol A Biol Sci Med Sci. 2017 Jan;72(1):30-37. Epub 2016 Mar 24.

PMID:
27013396
8.

Interplay between TDP-43 and docosahexaenoic acid-related processes in amyotrophic lateral sclerosis.

Cacabelos D, Ayala V, Granado-Serrano AB, Jové M, Torres P, Boada J, Cabré R, Ramírez-Núñez O, Gonzalo H, Soler-Cantero A, Serrano JC, Bellmunt MJ, Romero MP, Motilva MJ, Nonaka T, Hasegawa M, Ferrer I, Pamplona R, Portero-Otín M.

Neurobiol Dis. 2016 Apr;88:148-60. doi: 10.1016/j.nbd.2016.01.007. Epub 2016 Jan 12.

PMID:
26805387
9.

Neuroinflammatory Gene Regulation, Mitochondrial Function, Oxidative Stress, and Brain Lipid Modifications With Disease Progression in Tau P301S Transgenic Mice as a Model of Frontotemporal Lobar Degeneration-Tau.

López-González I, Aso E, Carmona M, Armand-Ugon M, Blanco R, Naudí A, Cabré R, Portero-Otin M, Pamplona R, Ferrer I.

J Neuropathol Exp Neurol. 2015 Oct;74(10):975-99. doi: 10.1097/NEN.0000000000000241.

PMID:
26360374
10.

Lipidomics of human brain aging and Alzheimer's disease pathology.

Naudí A, Cabré R, Jové M, Ayala V, Gonzalo H, Portero-Otín M, Ferrer I, Pamplona R.

Int Rev Neurobiol. 2015;122:133-89. doi: 10.1016/bs.irn.2015.05.008. Epub 2015 Jun 19. Review.

PMID:
26358893
11.

Plasma lipidomics discloses metabolic syndrome with a specific HDL phenotype.

Jové M, Naudí A, Portero-Otin M, Cabré R, Rovira-Llopis S, Bañuls C, Rocha M, Hernández-Mijares A, Victor VM, Pamplona R.

FASEB J. 2014 Dec;28(12):5163-71. doi: 10.1096/fj.14-253187. Epub 2014 Aug 28.

PMID:
25169057
12.

Dietary lipid unsaturation influences survival and oxidative modifications of an amyotrophic lateral sclerosis model in a gender-specific manner.

Cacabelos D, Ayala V, Ramírez-Nunez O, Granado-Serrano AB, Boada J, Serrano JC, Cabré R, Nadal-Rey G, Bellmunt MJ, Ferrer I, Pamplona R, Portero-Otin M.

Neuromolecular Med. 2014 Dec;16(4):669-85. doi: 10.1007/s12017-014-8317-7. Epub 2014 Jul 1.

PMID:
24980941
13.

Plasma long-chain free fatty acids predict mammalian longevity.

Jové M, Naudí A, Aledo JC, Cabré R, Ayala V, Portero-Otin M, Barja G, Pamplona R.

Sci Rep. 2013 Nov 28;3:3346. doi: 10.1038/srep03346.

14.

[A study of selective neuronal vulnerability in the human central nervous system].

Naudí A, Jové M, Ayala V, Cabré R, Portero-Otin M, Ferrer I, Pamplona R.

Rev Esp Geriatr Gerontol. 2013 Sep-Oct;48(5):216-23. doi: 10.1016/j.regg.2013.04.005. Epub 2013 Sep 5. Spanish.

PMID:
24011772
15.

Specific lipidome signatures in central nervous system from methionine-restricted mice.

Jové M, Ayala V, Ramírez-Núñez O, Naudí A, Cabré R, Spickett CM, Portero-Otín M, Pamplona R.

J Proteome Res. 2013 Jun 7;12(6):2679-89. doi: 10.1021/pr400064a. Epub 2013 Apr 30.

PMID:
23590626
16.

Non-enzymatic modification of aminophospholipids by carbonyl-amine reactions.

Naudí A, Jové M, Ayala V, Cabré R, Portero-Otín M, Pamplona R.

Int J Mol Sci. 2013 Feb 5;14(2):3285-313. doi: 10.3390/ijms14023285.

17.

Formation of S-(carboxymethyl)-cysteine in rat liver mitochondrial proteins: effects of caloric and methionine restriction.

Naudí A, Jové M, Cacabelos D, Ayala V, Cabre R, Caro P, Gomez J, Portero-Otín M, Barja G, Pamplona R.

Amino Acids. 2013 Feb;44(2):361-71. doi: 10.1007/s00726-012-1339-2. Epub 2012 Jun 22.

PMID:
22722543

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