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Items: 1 to 20 of 146

1.

Kidney-based in vitro models for drug-induced toxicity testing.

Faria J, Ahmed S, Gerritsen KGF, Mihaila SM, Masereeuw R.

Arch Toxicol. 2019 Dec;93(12):3397-3418. doi: 10.1007/s00204-019-02598-0. Epub 2019 Oct 29. Review.

PMID:
31664498
2.

Therapy with 2'-O-Me Phosphorothioate Antisense Oligonucleotides Causes Reversible Proteinuria by Inhibiting Renal Protein Reabsorption.

Janssen MJ, Nieskens TTG, Steevels TAM, Caetano-Pinto P, den Braanker D, Mulder M, Ponstein Y, Jones S, Masereeuw R, den Besten C, Wilmer MJ.

Mol Ther Nucleic Acids. 2019 Sep 6;18:298-307. doi: 10.1016/j.omtn.2019.08.025. [Epub ahead of print]

3.

In vitro nephrotoxicity and anticancer potency of newly synthesized cadmium complexes.

Abyar S, Khandar AA, Salehi R, Abolfazl Hosseini-Yazdi S, Alizadeh E, Mahkam M, Jamalpoor A, White JM, Shojaei M, Aizpurua-Olaizola O, Masereeuw R, Janssen MJ.

Sci Rep. 2019 Oct 11;9(1):14686. doi: 10.1038/s41598-019-51109-9.

4.

Quantitative Translation of Microfluidic Transporter in Vitro Data to in Vivo Reveals Impaired Albumin-Facilitated Indoxyl Sulfate Secretion in Chronic Kidney Disease.

van der Made TK, Fedecostante M, Scotcher D, Rostami-Hodjegan A, Sastre Toraño J, Middel I, Koster AS, Gerritsen KG, Jankowski V, Jankowski J, Hoenderop JGJ, Masereeuw R, Galetin A.

Mol Pharm. 2019 Nov 4;16(11):4551-4562. doi: 10.1021/acs.molpharmaceut.9b00681. Epub 2019 Sep 27.

PMID:
31525064
5.

Safety evaluation of conditionally immortalized cells for renal replacement therapy.

Mihajlovic M, Hariri S, Westphal KCG, Janssen MJ, Oost MJ, Bongiovanni L, van den Heuvel LP, de Bruin A, Hilbrands LB, Masereeuw R.

Oncotarget. 2019 Sep 3;10(51):5332-5348. doi: 10.18632/oncotarget.27152. eCollection 2019 Sep 3.

6.

Flow stimulates drug transport in a human kidney proximal tubule-on-a-chip independent of primary cilia.

Vriend J, Peters JGP, Nieskens TTG, Škovroňová R, Blaimschein N, Schmidts M, Roepman R, Schirris TJJ, Russel FGM, Masereeuw R, Wilmer MJ.

Biochim Biophys Acta Gen Subj. 2020 Jan;1864(1):129433. doi: 10.1016/j.bbagen.2019.129433. Epub 2019 Sep 11.

7.

A simple method for the isolation and detailed characterization of primary human proximal tubule cells for renal replacement therapy.

Sánchez-Romero N, Martínez-Gimeno L, Caetano-Pinto P, Saez B, Sánchez-Zalabardo JM, Masereeuw R, Giménez I.

Int J Artif Organs. 2019 Aug 6:391398819866458. doi: 10.1177/0391398819866458. [Epub ahead of print]

PMID:
31385550
8.

Remote sensing and signaling in kidney proximal tubules stimulates gut microbiome-derived organic anion secretion.

Jansen J, Jansen K, Neven E, Poesen R, Othman A, van Mil A, Sluijter J, Sastre Torano J, Zaal EA, Berkers CR, Esser D, Wichers HJ, van Ede K, van Duursen M, Burtey S, Verhaar MC, Meijers B, Masereeuw R.

Proc Natl Acad Sci U S A. 2019 Aug 6;116(32):16105-16110. doi: 10.1073/pnas.1821809116. Epub 2019 Jul 24.

9.

Selective Transport of Protein-Bound Uremic Toxins in Erythrocytes.

Deltombe O, Glorieux G, Marzouki S, Masereeuw R, Schneditz D, Eloot S.

Toxins (Basel). 2019 Jul 1;11(7). pii: E385. doi: 10.3390/toxins11070385.

10.

Outcome Definition Influences the Relationship Between Genetic Polymorphisms of ERCC1, ERCC2, SLC22A2 and Cisplatin Nephrotoxicity in Adult Testicular Cancer Patients.

Zazuli Z, Otten LS, Drögemöller BI, Medeiros M, Monzon JG, Wright GEB, Kollmannsberger CK, Bedard PL, Chen Z, Gelmon KA, McGoldrick N, Kitchlu A, Vijverberg SJH, Masereeuw R, Ross CJD, Liu G, Carleton BC, Maitland-van der Zee AH.

Genes (Basel). 2019 May 10;10(5). pii: E364. doi: 10.3390/genes10050364.

11.

Development and validation of bioengineered intestinal tubules for translational research aimed at safety and efficacy testing of drugs and nutrients.

Jochems PGM, van Bergenhenegouwen J, van Genderen AM, Eis ST, Wilod Versprille LJF, Wichers HJ, Jeurink PV, Garssen J, Masereeuw R.

Toxicol In Vitro. 2019 Oct;60:1-11. doi: 10.1016/j.tiv.2019.04.019. Epub 2019 May 6.

12.

Tubuloids derived from human adult kidney and urine for personalized disease modeling.

Schutgens F, Rookmaaker MB, Margaritis T, Rios A, Ammerlaan C, Jansen J, Gijzen L, Vormann M, Vonk A, Viveen M, Yengej FY, Derakhshan S, de Winter-de Groot KM, Artegiani B, van Boxtel R, Cuppen E, Hendrickx APA, van den Heuvel-Eibrink MM, Heitzer E, Lanz H, Beekman J, Murk JL, Masereeuw R, Holstege F, Drost J, Verhaar MC, Clevers H.

Nat Biotechnol. 2019 Mar;37(3):303-313. doi: 10.1038/s41587-019-0048-8. Epub 2019 Mar 4.

PMID:
30833775
13.

Are cell-based therapies for kidney disease safe? A systematic review of preclinical evidence.

Mihajlovic M, Wever KE, van der Made TK, de Vries RBM, Hilbrands LB, Masereeuw R.

Pharmacol Ther. 2019 May;197:191-211. doi: 10.1016/j.pharmthera.2019.01.004. Epub 2019 Jan 22. Review.

14.

Organic anion transporters 1 and 3 influence cellular energy metabolism in renal proximal tubule cells.

Vriend J, Hoogstraten CA, Venrooij KR, van den Berge BT, Govers LP, van Rooij A, Huigen MCDG, Schirris TJJ, Russel FGM, Masereeuw R, Wilmer MJ.

Biol Chem. 2019 Sep 25;400(10):1347-1358. doi: 10.1515/hsz-2018-0446.

PMID:
30653465
15.

Fabrication of Kidney Proximal Tubule Grafts Using Biofunctionalized Electrospun Polymer Scaffolds.

Jansen K, Castilho M, Aarts S, Kaminski MM, Lienkamp SS, Pichler R, Malda J, Vermonden T, Jansen J, Masereeuw R.

Macromol Biosci. 2019 Feb;19(2):e1800412. doi: 10.1002/mabi.201800412. Epub 2018 Dec 13.

PMID:
30548802
16.

Renal Epithelial Monolayer Formation on Monomeric and Polymeric Catechol Functionalized Supramolecular Biomaterials.

van Gaal RC, Fedecostante M, Fransen PKH, Masereeuw R, Dankers PYW.

Macromol Biosci. 2019 Feb;19(2):e1800300. doi: 10.1002/mabi.201800300. Epub 2018 Nov 14.

PMID:
30430737
17.

Phase I/II Trial of a Combination of Anti-CD3/CD7 Immunotoxins for Steroid-Refractory Acute Graft-versus-Host Disease.

Groth C, van Groningen LFJ, Matos TR, Bremmers ME, Preijers FWMB, Dolstra H, Reicherts C, Schaap NPM, van Hooren EHG, IntHout J, Masereeuw R, Netea MG, Levine JE, Morales G, Ferrara JL, Blijlevens NMA, van Oosterhout YVJM, Stelljes M, van der Velden WJFM.

Biol Blood Marrow Transplant. 2019 Apr;25(4):712-719. doi: 10.1016/j.bbmt.2018.10.020. Epub 2018 Nov 3.

PMID:
30399420
18.

Genetic Variations and Cisplatin Nephrotoxicity: A Systematic Review.

Zazuli Z, Vijverberg S, Slob E, Liu G, Carleton B, Veltman J, Baas P, Masereeuw R, Maitland-van der Zee AH.

Front Pharmacol. 2018 Sep 27;9:1111. doi: 10.3389/fphar.2018.01111. eCollection 2018.

19.

Bioengineering Organs for Blood Detoxification.

Legallais C, Kim D, Mihaila SM, Mihajlovic M, Figliuzzi M, Bonandrini B, Salerno S, Yousef Yengej FA, Rookmaaker MB, Sanchez Romero N, Sainz-Arnal P, Pereira U, Pasqua M, Gerritsen KGF, Verhaar MC, Remuzzi A, Baptista PM, De Bartolo L, Masereeuw R, Stamatialis D.

Adv Healthc Mater. 2018 Nov;7(21):e1800430. doi: 10.1002/adhm.201800430. Epub 2018 Sep 19. Review.

PMID:
30230709
20.

Adding the T to ADME: Predictive Toxicity in Renal Drug Development.

Lai RE, Masereeuw R.

AAPS J. 2018 Sep 5;20(6):98. doi: 10.1208/s12248-018-0258-x. No abstract available.

PMID:
30187254

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