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Items: 13

1.

Integrative proteomic and functional analyses provide novel insights into the action of the repurposed drug candidate nitroxoline in AsPC-1 cells.

Veschi S, Ronci M, Lanuti P, De Lellis L, Florio R, Bologna G, Scotti L, Carletti E, Brugnoli F, Di Bella MC, Bertagnolo V, Marchisio M, Cama A.

Sci Rep. 2020 Feb 13;10(1):2574. doi: 10.1038/s41598-020-59492-4.

2.

The Benzimidazole-Based Anthelmintic Parbendazole: A Repurposed Drug Candidate That Synergizes with Gemcitabine in Pancreatic Cancer.

Florio R, Veschi S, di Giacomo V, Pagotto S, Carradori S, Verginelli F, Cirilli R, Casulli A, Grassadonia A, Tinari N, Cataldi A, Amoroso R, Cama A, De Lellis L.

Cancers (Basel). 2019 Dec 17;11(12). pii: E2042. doi: 10.3390/cancers11122042.

3.

Synthesis of novel benzothiazole amides: Evaluation of PPAR activity and anti-proliferative effects in paraganglioma, pancreatic and colorectal cancer cell lines.

Ammazzalorso A, De Lellis L, Florio R, Laghezza A, De Filippis B, Fantacuzzi M, Giampietro L, Maccallini C, Tortorella P, Veschi S, Loiodice F, Cama A, Amoroso R.

Bioorg Med Chem Lett. 2019 Aug 15;29(16):2302-2306. doi: 10.1016/j.bmcl.2019.06.020. Epub 2019 Jun 18.

PMID:
31272790
4.

Novel Phenyldiazenyl Fibrate Analogues as PPAR α/γ/δ Pan-Agonists for the Amelioration of Metabolic Syndrome.

Giampietro L, Laghezza A, Cerchia C, Florio R, Recinella L, Capone F, Ammazzalorso A, Bruno I, De Filippis B, Fantacuzzi M, Ferrante C, Maccallini C, Tortorella P, Verginelli F, Brunetti L, Cama A, Amoroso R, Loiodice F, Lavecchia A.

ACS Med Chem Lett. 2019 Feb 25;10(4):545-551. doi: 10.1021/acsmedchemlett.8b00574. eCollection 2019 Apr 11.

PMID:
30996794
5.

Effects of repurposed drug candidates nitroxoline and nelfinavir as single agents or in combination with erlotinib in pancreatic cancer cells.

Veschi S, De Lellis L, Florio R, Lanuti P, Massucci A, Tinari N, De Tursi M, di Sebastiano P, Marchisio M, Natoli C, Cama A.

J Exp Clin Cancer Res. 2018 Sep 21;37(1):236. doi: 10.1186/s13046-018-0904-2.

6.

Effects of dichloroacetate as single agent or in combination with GW6471 and metformin in paraganglioma cells.

Florio R, De Lellis L, Veschi S, Verginelli F, di Giacomo V, Gallorini M, Perconti S, Sanna M, Mariani-Costantini R, Natale A, Arduini A, Amoroso R, Cataldi A, Cama A.

Sci Rep. 2018 Sep 11;8(1):13610. doi: 10.1038/s41598-018-31797-5.

7.

Correction to: Paragangliomas arise through an autonomous vasculo-angio-neurogenic program inhibited by imatinib.

Verginelli F, Perconti S, Vespa S, Schiavi F, Prasad SC, Lanuti P, Cama A, Tramontana L, Esposito DL, Guarnieri S, Sheu A, Pantalone MR, Florio R, Morgano A, Rossi C, Bologna G, Marchisio M, D'Argenio A, Taschin E, Visone R, Opocher G, Veronese A, Paties CT, Rajasekhar VK, Söderberg-Nauclér C, Sanna M, Lotti LV, Mariani-Costantini R.

Acta Neuropathol. 2018 May;135(5):799. doi: 10.1007/s00401-018-1811-5.

8.

Paragangliomas arise through an autonomous vasculo-angio-neurogenic program inhibited by imatinib.

Verginelli F, Perconti S, Vespa S, Schiavi F, Prasad SC, Lanuti P, Cama A, Tramontana L, Esposito DL, Guarnieri S, Sheu A, Pantalone MR, Florio R, Morgano A, Rossi C, Bologna G, Marchisio M, D'Argenio A, Taschin E, Visone R, Opocher G, Veronese A, Paties CT, Rajasekhar VK, Söderberg-Nauclér C, Sanna M, Lotti LV, Mariani-Costantini R.

Acta Neuropathol. 2018 May;135(5):779-798. doi: 10.1007/s00401-017-1799-2. Epub 2018 Jan 5. Erratum in: Acta Neuropathol. 2018 Feb 1;:.

9.

Effects of PPARα inhibition in head and neck paraganglioma cells.

Florio R, De Lellis L, di Giacomo V, Di Marcantonio MC, Cristiano L, Basile M, Verginelli F, Verzilli D, Ammazzalorso A, Prasad SC, Cataldi A, Sanna M, Cimini A, Mariani-Costantini R, Mincione G, Cama A.

PLoS One. 2017 Jun 8;12(6):e0178995. doi: 10.1371/journal.pone.0178995. eCollection 2017.

10.

Cytotoxic effect of a family of peroxisome proliferator-activated receptor antagonists in colorectal and pancreatic cancer cell lines.

Ammazzalorso A, De Lellis L, Florio R, Bruno I, De Filippis B, Fantacuzzi M, Giampietro L, Maccallini C, Perconti S, Verginelli F, Cama A, Amoroso R.

Chem Biol Drug Des. 2017 Nov;90(5):1029-1035. doi: 10.1111/cbdd.13026. Epub 2017 Jul 19.

PMID:
28544586
11.

Open saccharin-based secondary sulfonamides as potent and selective inhibitors of cancer-related carbonic anhydrase IX and XII isoforms.

D'Ascenzio M, Guglielmi P, Carradori S, Secci D, Florio R, Mollica A, Ceruso M, Akdemir A, Sobolev AP, Supuran CT.

J Enzyme Inhib Med Chem. 2017 Dec;32(1):51-59. doi: 10.1080/14756366.2016.1235040. Epub 2016 Oct 26.

12.

Low AMY1 Gene Copy Number Is Associated with Increased Body Mass Index in Prepubertal Boys.

Marcovecchio ML, Florio R, Verginelli F, De Lellis L, Capelli C, Verzilli D, Chiarelli F, Mohn A, Cama A.

PLoS One. 2016 May 5;11(5):e0154961. doi: 10.1371/journal.pone.0154961. eCollection 2016.

13.

Synthesis, in vitro evaluation, and molecular modeling investigation of benzenesulfonimide peroxisome proliferator-activated receptors α antagonists.

Ammazzalorso A, Carrieri A, Verginelli F, Bruno I, Carbonara G, D'Angelo A, De Filippis B, Fantacuzzi M, Florio R, Fracchiolla G, Giampietro L, Giancristofaro A, Maccallini C, Cama A, Amoroso R.

Eur J Med Chem. 2016 May 23;114:191-200. doi: 10.1016/j.ejmech.2016.02.064. Epub 2016 Feb 27.

PMID:
26974385

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