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Items: 1 to 20 of 26

1.

TSPO-targeted NIR-fluorescent ultra-small iron oxide nanoparticles for glioblastoma imaging.

Denora N, Lee C, Iacobazzi RM, Choi JY, Song IH, Yoo JS, Piao Y, Lopalco A, Leonetti F, Lee BC, Kim SE.

Eur J Pharm Sci. 2019 Aug 15;139:105047. doi: 10.1016/j.ejps.2019.105047. [Epub ahead of print]

PMID:
31422171
2.

Gene Expression Comparison between the Lymph Node-Positive and -Negative Reveals a Peculiar Immune Microenvironment Signature and a Theranostic Role for WNT Targeting in Pancreatic Ductal Adenocarcinoma: A Pilot Study.

Argentiero A, De Summa S, Di Fonte R, Iacobazzi RM, Porcelli L, Da Vià M, Brunetti O, Azzariti A, Silvestris N, Solimando AG.

Cancers (Basel). 2019 Jul 4;11(7). pii: E942. doi: 10.3390/cancers11070942.

3.

Green Fluorescent Terbium (III) Complex Doped Silica Nanoparticles.

Fanizza E, Depalo N, Fedorenko S, Iacobazzi RM, Mukhametshina A, Zairov R, Salatino A, Vischio F, Panniello A, Laquintana V, Curri ML, Mustafina A, Denora N, Striccoli M.

Int J Mol Sci. 2019 Jun 27;20(13). pii: E3139. doi: 10.3390/ijms20133139.

4.

1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity.

Franchini S, Sorbi C, Linciano P, Carnevale G, Tait A, Ronsisvalle S, Buccioni M, Del Bello F, Cilia A, Pirona L, Denora N, Iacobazzi RM, Brasili L.

Eur J Med Chem. 2019 Aug 15;176:310-325. doi: 10.1016/j.ejmech.2019.05.024. Epub 2019 May 11.

PMID:
31112892
5.

CAFs and TGF-β Signaling Activation by Mast Cells Contribute to Resistance to Gemcitabine/Nabpaclitaxel in Pancreatic Cancer.

Porcelli L, Iacobazzi RM, Di Fonte R, Serratì S, Intini A, Solimando AG, Brunetti O, Calabrese A, Leonetti F, Azzariti A, Silvestris N.

Cancers (Basel). 2019 Mar 7;11(3). pii: E330. doi: 10.3390/cancers11030330.

6.

Plasma-activated medium triggers cell death and the presentation of immune activating danger signals in melanoma and pancreatic cancer cells.

Azzariti A, Iacobazzi RM, Di Fonte R, Porcelli L, Gristina R, Favia P, Fracassi F, Trizio I, Silvestris N, Guida G, Tommasi S, Sardella E.

Sci Rep. 2019 Mar 11;9(1):4099. doi: 10.1038/s41598-019-40637-z.

7.

Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3.

Oukoloff K, Coquelle N, Bartolini M, Naldi M, Le Guevel R, Bach S, Josselin B, Ruchaud S, Catto M, Pisani L, Denora N, Iacobazzi RM, Silman I, Sussman JL, Buron F, Colletier JP, Jean L, Routier S, Renard PY.

Eur J Med Chem. 2019 Apr 15;168:58-77. doi: 10.1016/j.ejmech.2018.12.063. Epub 2019 Feb 13.

8.

Investigating alkyl nitrates as nitric oxide releasing precursors of multitarget acetylcholinesterase-monoamine oxidase B inhibitors.

Pisani L, Iacobazzi RM, Catto M, Rullo M, Farina R, Denora N, Cellamare S, Altomare CD.

Eur J Med Chem. 2019 Jan 1;161:292-309. doi: 10.1016/j.ejmech.2018.10.016. Epub 2018 Oct 10.

PMID:
30366255
9.

Synthesis and biological evaluation of 1,3-dioxolane-based 5-HT1A receptor agonists for CNS disorders and neuropathic pain.

Franchini S, Bencheva LI, Battisti UM, Tait A, Sorbi C, Fossa P, Cichero E, Ronsisvalle S, Aricò G, Denora N, Iacobazzi RM, Cilia A, Pirona L, Brasili L.

Future Med Chem. 2018 Sep 1;10(18):2137-2154. doi: 10.4155/fmc-2018-0107. Epub 2018 Jul 25.

PMID:
30043643
10.

Delivery of Proapoptotic Agents in Glioma Cell Lines by TSPO Ligand-Dextran Nanogels.

Lopalco A, Cutrignelli A, Denora N, Perrone M, Iacobazzi RM, Fanizza E, Lopedota A, Depalo N, de Candia M, Franco M, Laquintana V.

Int J Mol Sci. 2018 Apr 11;19(4). pii: E1155. doi: 10.3390/ijms19041155.

11.

Grape seed extracts modify the outcome of oxaliplatin in colon cancer cells by interfering with cellular mechanisms of drug cytotoxicity.

Porcelli L, Iacobazzi RM, Quatrale AE, Bergamini C, Denora N, Crupi P, Antonacci D, Mangia A, Simone G, Silvestris N, Azzariti A.

Oncotarget. 2017 Feb 7;8(31):50845-50863. doi: 10.18632/oncotarget.15139. eCollection 2017 Aug 1.

12.

Novel chemotypes targeting tubulin at the colchicine binding site and unbiasing P-glycoprotein.

Mangiatordi GF, Trisciuzzi D, Alberga D, Denora N, Iacobazzi RM, Gadaleta D, Catto M, Nicolotti O.

Eur J Med Chem. 2017 Oct 20;139:792-803. doi: 10.1016/j.ejmech.2017.07.037. Epub 2017 Jul 21.

PMID:
28863359
13.

Bridging Pharmaceutical Chemistry with Drug and Nanoparticle Targeting to Investigate the Role of the 18-kDa Translocator Protein TSPO.

Iacobazzi RM, Lopalco A, Cutrignelli A, Laquintana V, Lopedota A, Franco M, Denora N.

ChemMedChem. 2017 Aug 22;12(16):1261-1274. doi: 10.1002/cmdc.201700322. Epub 2017 Aug 3. Review.

PMID:
28771957
14.

Targeting human liver cancer cells with lactobionic acid-G(4)-PAMAM-FITC sorafenib loaded dendrimers.

Iacobazzi RM, Porcelli L, Lopedota AA, Laquintana V, Lopalco A, Cutrignelli A, Altamura E, Di Fonte R, Azzariti A, Franco M, Denora N.

Int J Pharm. 2017 Aug 7;528(1-2):485-497. doi: 10.1016/j.ijpharm.2017.06.049. Epub 2017 Jun 15.

PMID:
28624661
15.

Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists.

Franchini S, Manasieva LI, Sorbi C, Battisti UM, Fossa P, Cichero E, Denora N, Iacobazzi RM, Cilia A, Pirona L, Ronsisvalle S, Aricò G, Brasili L.

Eur J Med Chem. 2017 Jan 5;125:435-452. doi: 10.1016/j.ejmech.2016.09.050. Epub 2016 Sep 17.

PMID:
27689727
16.

Potential predictive role of chemotherapy-induced changes of soluble CD40 ligand in untreated advanced pancreatic ductal adenocarcinoma.

Azzariti A, Brunetti O, Porcelli L, Graziano G, Iacobazzi RM, Signorile M, Scarpa A, Lorusso V, Silvestris N.

Onco Targets Ther. 2016 Jul 28;9:4681-6. doi: 10.2147/OTT.S106496. eCollection 2016.

17.

Synthesis and Evaluation of Tricarbonyl (99m)Tc-Labeled 2-(4-Chloro)phenyl-imidazo[1,2-a]pyridine Analogs as Novel SPECT Imaging Radiotracer for TSPO-Rich Cancer.

Choi JY, Iacobazzi RM, Perrone M, Margiotta N, Cutrignelli A, Jung JH, Park do D, Moon BS, Denora N, Kim SE, Lee BC.

Int J Mol Sci. 2016 Jul 7;17(7). pii: E1085. doi: 10.3390/ijms17071085.

18.

Synthesis and Evaluation of Tricarbonyl (99m)Tc-Labeled 2-(4-Chloro)phenyl-imidazo[1,2-a]pyridine Analogs as Novel SPECT Imaging Radiotracer for TSPO-Rich Cancer.

Choi JY, Iacobazzi RM, Perrone M, Margiotta N, Cutrignelli A, Jung JH, Park do D, Moon BS, Denora N, Kim SE, Lee BC.

Int J Mol Sci. 2016 Jul 7;17(7). pii: E1085. doi: 10.3390/ijms17071085.

19.

Synthesis and Evaluation of Tricarbonyl (99m)Tc-Labeled 2-(4-Chloro)phenyl-imidazo[1,2-a]pyridine Analogs as Novel SPECT Imaging Radiotracer for TSPO-Rich Cancer.

Choi JY, Iacobazzi RM, Perrone M, Margiotta N, Cutrignelli A, Jung JH, Park do D, Moon BS, Denora N, Kim SE, Lee BC.

Int J Mol Sci. 2016 Jul 7;17(7). pii: E1085. doi: 10.3390/ijms17071085.

20.

Synthesis, Characterization, and Cytotoxicity of the First Oxaliplatin Pt(IV) Derivative Having a TSPO Ligand in the Axial Position.

Savino S, Denora N, Iacobazzi RM, Porcelli L, Azzariti A, Natile G, Margiotta N.

Int J Mol Sci. 2016 Jun 25;17(7). pii: E1010. doi: 10.3390/ijms17071010.

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