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Items: 16


Calpain Inhibition Increases SMN Protein in Spinal Cord Motoneurons and Ameliorates the Spinal Muscular Atrophy Phenotype in Mice.

de la Fuente S, Sansa A, Periyakaruppiah A, Garcera A, Soler RM.

Mol Neurobiol. 2019 Jun;56(6):4414-4427. doi: 10.1007/s12035-018-1379-z. Epub 2018 Oct 16.


Inhibition of autophagy delays motoneuron degeneration and extends lifespan in a mouse model of spinal muscular atrophy.

Piras A, Schiaffino L, Boido M, Valsecchi V, Guglielmotto M, De Amicis E, Puyal J, Garcera A, Tamagno E, Soler RM, Vercelli A.

Cell Death Dis. 2017 Dec 20;8(12):3223. doi: 10.1038/s41419-017-0086-4.


Smn-Deficiency Increases the Intrinsic Excitability of Motoneurons.

Arumugam S, Garcera A, Soler RM, Tabares L.

Front Cell Neurosci. 2017 Sep 5;11:269. doi: 10.3389/fncel.2017.00269. eCollection 2017.


Regulation of Survival Motor Neuron Protein by the Nuclear Factor-Kappa B Pathway in Mouse Spinal Cord Motoneurons.

Arumugam S, Mincheva-Tasheva S, Periyakaruppiah A, de la Fuente S, Soler RM, Garcera A.

Mol Neurobiol. 2018 Jun;55(6):5019-5030. doi: 10.1007/s12035-017-0710-4. Epub 2017 Aug 14.


Autophagy modulators regulate survival motor neuron protein stability in motoneurons.

Periyakaruppiah A, de la Fuente S, Arumugam S, Bahí N, Garcera A, Soler RM.

Exp Neurol. 2016 Sep;283(Pt A):287-97. doi: 10.1016/j.expneurol.2016.06.032. Epub 2016 Jun 30. No abstract available.


Calpain activation and CaMKIV reduction in spinal cords from hSOD1G93A mouse model.

Gou-Fabregas M, Ramírez-Núñez O, Cacabelos D, Bahi N, Portero M, Garcera A, Soler RM.

Mol Cell Neurosci. 2014 Jul;61:219-25. doi: 10.1016/j.mcn.2014.07.002. Epub 2014 Jul 22.


Notch signaling pathway is activated in motoneurons of spinal muscular atrophy.

Caraballo-Miralles V, Cardona-Rossinyol A, Garcera A, Torres-Benito L, Soler RM, Tabares L, Lladó J, Olmos G.

Int J Mol Sci. 2013 May 29;14(6):11424-37. doi: 10.3390/ijms140611424.


NF-κB signaling pathways: role in nervous system physiology and pathology.

Mincheva-Tasheva S, Soler RM.

Neuroscientist. 2013 Apr;19(2):175-94. doi: 10.1177/1073858412444007. Epub 2012 Jul 10. Review.


SMN deficiency attenuates migration of U87MG astroglioma cells through the activation of RhoA.

Caraballo-Miralles V, Cardona-Rossinyol A, Garcera A, Villalonga P, Soler RM, Olmos G, Lladó J.

Mol Cell Neurosci. 2012 Mar;49(3):282-9. doi: 10.1016/j.mcn.2011.12.003. Epub 2011 Dec 16.


The canonical nuclear factor-κB pathway regulates cell survival in a developmental model of spinal cord motoneurons.

Mincheva S, Garcera A, Gou-Fabregas M, Encinas M, Dolcet X, Soler RM.

J Neurosci. 2011 Apr 27;31(17):6493-503. doi: 10.1523/JNEUROSCI.0206-11.2011.


A new model to study spinal muscular atrophy: neurite degeneration and cell death is counteracted by BCL-X(L) Overexpression in motoneurons.

Garcera A, Mincheva S, Gou-Fabregas M, Caraballo-Miralles V, Lladó J, Comella JX, Soler RM.

Neurobiol Dis. 2011 Jun;42(3):415-26. doi: 10.1016/j.nbd.2011.02.003. Epub 2011 Feb 16.


The death receptor antagonist FLIP-L interacts with Trk and is necessary for neurite outgrowth induced by neurotrophins.

Moubarak RS, Solé C, Pascual M, Gutierrez H, Llovera M, Pérez-García MJ, Gozzelino R, Segura MF, Iglesias-Guimarais V, Reix S, Soler RM, Davies AM, Soriano E, Yuste VJ, Comella JX.

J Neurosci. 2010 Apr 28;30(17):6094-105. doi: 10.1523/JNEUROSCI.0537-10.2010.


Specific vulnerability of mouse spinal cord motoneurons to membrane depolarization.

Gou-Fabregas M, Garcera A, Mincheva S, Perez-Garcia MJ, Comella JX, Soler RM.

J Neurochem. 2009 Sep;110(6):1842-54. doi: 10.1111/j.1471-4159.2009.06278.x. Epub 2009 Jul 13.


Tyr-701 is a new regulatory site for neurotrophin receptor TrkA trafficking and function.

de Pablo Y, Pérez-García MJ, Georgieva MV, Sanchis D, Lindqvist N, Soler RM, Comella JX, Llovera M.

J Neurochem. 2008 Jan;104(1):124-39. doi: 10.1111/j.1471-4159.2007.05027.x.


Neuroprotection by neurotrophic factors and membrane depolarization is regulated by calmodulin kinase IV.

Pérez-García MJ, Gou-Fabregas M, de Pablo Y, Llovera M, Comella JX, Soler RM.

J Biol Chem. 2008 Feb 15;283(7):4133-44. Epub 2007 Dec 13.


Glial cell line-derived neurotrophic factor increases intracellular calcium concentration. Role of calcium/calmodulin in the activation of the phosphatidylinositol 3-kinase pathway.

Pérez-García MJ, Ceña V, de Pablo Y, Llovera M, Comella JX, Soler RM.

J Biol Chem. 2004 Feb 13;279(7):6132-42. Epub 2003 Nov 20.

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