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Items: 1 to 20 of 72

1.

Choroid plexus-derived miR-204 regulates the number of quiescent neural stem cells in the adult brain.

Lepko T, Pusch M, Müller T, Schulte D, Ehses J, Kiebler M, Hasler J, Huttner HB, Vandenbroucke RE, Vandendriessche C, Modic M, Martin-Villalba A, Zhao S, LLorens-Bobadilla E, Schneider A, Fischer A, Breunig CT, Stricker SH, Götz M, Ninkovic J.

EMBO J. 2019 Jul 15:e100481. doi: 10.15252/embj.2018100481. [Epub ahead of print]

PMID:
31304985
2.

A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment.

Van Hove H, Martens L, Scheyltjens I, De Vlaminck K, Pombo Antunes AR, De Prijck S, Vandamme N, De Schepper S, Van Isterdael G, Scott CL, Aerts J, Berx G, Boeckxstaens GE, Vandenbroucke RE, Vereecke L, Moechars D, Guilliams M, Van Ginderachter JA, Saeys Y, Movahedi K.

Nat Neurosci. 2019 Jun;22(6):1021-1035. doi: 10.1038/s41593-019-0393-4. Epub 2019 May 6.

PMID:
31061494
3.

Choroid plexus tumor necrosis factor receptor 1: A new neuroinflammatory piece of the complex Alzheimer's disease puzzle.

Steeland S, Vandenbroucke RE.

Neural Regen Res. 2019 Jul;14(7):1144-1147. doi: 10.4103/1673-5374.247443.

4.

The N-terminal p.(Ser38Cys) TIMP3 mutation underlying Sorsby fundus dystrophy is a founder mutation disrupting an intramolecular disulfide bond.

Naessens S, De Zaeytijd J, Syx D, Vandenbroucke RE, Smeets F, Van Cauwenbergh C, Leroy BP, Peelman F, Coppieters F.

Hum Mutat. 2019 May;40(5):539-551. doi: 10.1002/humu.23713. Epub 2019 Feb 6.

5.

Overexpression of Gilz Protects Mice Against Lethal Septic Peritonitis.

Ballegeer M, Vandewalle J, Eggermont M, Van Isterdael G, Dejager L, De Bus L, Decruyenaere J, Vandenbroucke RE, Libert C.

Shock. 2019 Aug;52(2):208-214. doi: 10.1097/SHK.0000000000001252.

PMID:
30124596
6.

A New Venue of TNF Targeting.

Steeland S, Libert C, Vandenbroucke RE.

Int J Mol Sci. 2018 May 11;19(5). pii: E1442. doi: 10.3390/ijms19051442. Review.

7.

Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice.

Ballegeer M, Van Looveren K, Timmermans S, Eggermont M, Vandevyver S, Thery F, Dendoncker K, Souffriau J, Vandewalle J, Van Wyngene L, De Rycke R, Takahashi N, Vandenabeele P, Tuckermann J, Reichardt HM, Impens F, Beyaert R, De Bosscher K, Vandenbroucke RE, Libert C.

J Clin Invest. 2018 Aug 1;128(8):3265-3279. doi: 10.1172/JCI96636. Epub 2018 Jun 25.

8.

Counteracting the effects of TNF receptor-1 has therapeutic potential in Alzheimer's disease.

Steeland S, Gorlé N, Vandendriessche C, Balusu S, Brkic M, Van Cauwenberghe C, Van Imschoot G, Van Wonterghem E, De Rycke R, Kremer A, Lippens S, Stopa E, Johanson CE, Libert C, Vandenbroucke RE.

EMBO Mol Med. 2018 Apr;10(4). pii: e8300. doi: 10.15252/emmm.201708300.

9.

Quantifying the Average Number of Nucleic Acid Therapeutics per Nanocarrier by Single Particle Tracking Microscopy.

Zagato E, Vermeulen L, Dewitte H, Van Imschoot G, Vandenbroucke RE, Demeester J, De Smedt SC, Neyts K, Remaut K, Braeckmans K.

Mol Pharm. 2018 Mar 5;15(3):1142-1149. doi: 10.1021/acs.molpharmaceut.7b00999. Epub 2018 Feb 19.

PMID:
29433310
10.

Correction to: Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017.

Greenwood J, Hammarlund-Udenaes M, Jones HC, Stitt AW, Vandenbroucke RE, Romero IA, Campbell M, Fricker G, Brodin B, Manninga H, Gaillard PJ, Schwaninger M, Webster C, Wicher KB, Khrestchatisky M.

Fluids Barriers CNS. 2018 Jan 12;15(1):3. doi: 10.1186/s12987-017-0086-x.

11.

Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017.

Greenwood J, Hammarlund-Udenaes M, Jones HC, Stitt AW, Vandenbroucke RE, Romero IA, Campbell M, Fricker G, Brodin B, Manninga H, Gaillard PJ, Schwaninger M, Webster C, Wicher KB, Khrestchatisky M.

Fluids Barriers CNS. 2017 Nov 7;14(1):31. doi: 10.1186/s12987-017-0079-9. Erratum in: Fluids Barriers CNS. 2018 Jan 12;15(1):3.

12.

Simultaneous Inhibition of Tumor Necrosis Factor Receptor 1 and Matrix Metalloproteinase 8 Completely Protects Against Acute Inflammation and Sepsis.

Steeland S, Van Ryckeghem S, Vandewalle J, Ballegeer M, Van Wonterghem E, Eggermont M, Decruyenaere J, De Bus L, Libert C, Vandenbroucke RE.

Crit Care Med. 2018 Jan;46(1):e67-e75. doi: 10.1097/CCM.0000000000002813.

PMID:
29095202
13.

TNFR1 inhibition with a Nanobody protects against EAE development in mice.

Steeland S, Van Ryckeghem S, Van Imschoot G, De Rycke R, Toussaint W, Vanhoutte L, Vanhove C, De Vos F, Vandenbroucke RE, Libert C.

Sci Rep. 2017 Oct 20;7(1):13646. doi: 10.1038/s41598-017-13984-y.

14.

Treatment of Intestinal Fibrosis in Experimental Inflammatory Bowel Disease by the Pleiotropic Actions of a Local Rho Kinase Inhibitor.

Holvoet T, Devriese S, Castermans K, Boland S, Leysen D, Vandewynckel YP, Devisscher L, Van den Bossche L, Van Welden S, Dullaers M, Vandenbroucke RE, De Rycke R, Geboes K, Bourin A, Defert O, Hindryckx P, De Vos M, Laukens D.

Gastroenterology. 2017 Oct;153(4):1054-1067. doi: 10.1053/j.gastro.2017.06.013. Epub 2017 Jun 19.

PMID:
28642198
15.

A Hidden Epithelial Barrier in the Brain with a Central Role in Regulating Brain Homeostasis. Implications for Aging.

Vandenbroucke RE.

Ann Am Thorac Soc. 2016 Dec;13 Suppl 5:S407-S410. doi: 10.1513/AnnalsATS.201609-676AW. Review.

PMID:
28005425
16.

Mouse models of ageing and their relevance to disease.

Kõks S, Dogan S, Tuna BG, González-Navarro H, Potter P, Vandenbroucke RE.

Mech Ageing Dev. 2016 Dec;160:41-53. doi: 10.1016/j.mad.2016.10.001. Epub 2016 Oct 4. Review.

17.

Sizing nanomaterials in bio-fluids by cFRAP enables protein aggregation measurements and diagnosis of bio-barrier permeability.

Xiong R, Vandenbroucke RE, Broos K, Brans T, Van Wonterghem E, Libert C, Demeester J, De Smedt SC, Braeckmans K.

Nat Commun. 2016 Sep 22;7:12982. doi: 10.1038/ncomms12982.

18.

Identification of a novel mechanism of blood-brain communication during peripheral inflammation via choroid plexus-derived extracellular vesicles.

Balusu S, Van Wonterghem E, De Rycke R, Raemdonck K, Stremersch S, Gevaert K, Brkic M, Demeestere D, Vanhooren V, Hendrix A, Libert C, Vandenbroucke RE.

EMBO Mol Med. 2016 Oct 4;8(10):1162-1183. doi: 10.15252/emmm.201606271. Print 2016 Oct.

19.

Corrigendum: Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation.

Kessler SM, Laggai S, Van Wonterghem E, Gemperlein K, Müller R, Haybaeck J, Vandenbroucke RE, Ogris M, Libert C, Kiemer AK.

Front Physiol. 2016 Jul 29;7:328. doi: 10.3389/fphys.2016.00328. eCollection 2016.

20.

With mouse age comes wisdom: A review and suggestions of relevant mouse models for age-related conditions.

Drechsler S, Lynch MA, Novella S, González-Navarro H, Hecimovic S, Barini E, Tucci V, Castro RE, Vandenbroucke RE, Osuchowski M, Potter PK.

Mech Ageing Dev. 2016 Dec;160:54-68. doi: 10.1016/j.mad.2016.07.005. Epub 2016 Jul 21. Review.

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