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Items: 1 to 20 of 37

1.

Determining the Replication Kinetics and Cellular Tropism of Influenza D Virus on Primary Well-Differentiated Human Airway Epithelial Cells.

Holwerda M, Kelly J, Laloli L, Stürmer I, Portmann J, Stalder H, Dijkman R.

Viruses. 2019 Apr 24;11(4). pii: E377. doi: 10.3390/v11040377.

2.

Determination of host proteins composing the microenvironment of coronavirus replicase complexes by proximity-labeling.

V'kovski P, Gerber M, Kelly J, Pfaender S, Ebert N, Braga Lagache S, Simillion C, Portmann J, Stalder H, Gaschen V, Bruggmann R, Stoffel MH, Heller M, Dijkman R, Thiel V.

Elife. 2019 Jan 11;8. pii: e42037. doi: 10.7554/eLife.42037.

3.

Host switching pathogens, infectious outbreaks and zoonosis: A Marie Skłodowska-Curie innovative training network (HONOURs).

van der Hoek L, Verschoor E, Beer M, Höper D, Wernike K, Van Ranst M, Matthijnssens J, Maes P, Sastre P, Rueda P, Drexler JF, Barr J, Edwards T, Millner P, Vermeij P, de Groof A, Thiel V, Dijkman R, Suter-Riniker F, Leib S, Koller R, Ramette A, Engler O, Beuret C.

Virus Res. 2018 Sep 15;257:120-124. doi: 10.1016/j.virusres.2018.09.002.

4.

Attenuation of replication by a 29 nucleotide deletion in SARS-coronavirus acquired during the early stages of human-to-human transmission.

Muth D, Corman VM, Roth H, Binger T, Dijkman R, Gottula LT, Gloza-Rausch F, Balboni A, Battilani M, Rihtarič D, Toplak I, Ameneiros RS, Pfeifer A, Thiel V, Drexler JF, Müller MA, Drosten C.

Sci Rep. 2018 Oct 11;8(1):15177. doi: 10.1038/s41598-018-33487-8.

5.

Targeting of the Nasal Mucosa by Japanese Encephalitis Virus for Non-Vector-Borne Transmission.

García-Nicolás O, Braun RO, Milona P, Lewandowska M, Dijkman R, Alves MP, Summerfield A.

J Virol. 2018 Nov 27;92(24). pii: e01091-18. doi: 10.1128/JVI.01091-18. Print 2018 Dec 15.

6.

The papain-like protease determines a virulence trait that varies among members of the SARS-coronavirus species.

Niemeyer D, Mösbauer K, Klein EM, Sieberg A, Mettelman RC, Mielech AM, Dijkman R, Baker SC, Drosten C, Müller MA.

PLoS Pathog. 2018 Sep 24;14(9):e1007296. doi: 10.1371/journal.ppat.1007296. eCollection 2018 Sep.

7.

Phosphoproteomic-based kinase profiling early in influenza virus infection identifies GRK2 as antiviral drug target.

Yángüez E, Hunziker A, Dobay MP, Yildiz S, Schading S, Elshina E, Karakus U, Gehrig P, Grossmann J, Dijkman R, Schmolke M, Stertz S.

Nat Commun. 2018 Sep 11;9(1):3679. doi: 10.1038/s41467-018-06119-y.

8.

Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses.

Siddharta A, Pfaender S, Vielle NJ, Dijkman R, Friesland M, Becker B, Yang J, Engelmann M, Todt D, Windisch MP, Brill FH, Steinmann J, Steinmann J, Becker S, Alves MP, Pietschmann T, Eickmann M, Thiel V, Steinmann E.

J Infect Dis. 2017 Mar 15;215(6):902-906. doi: 10.1093/infdis/jix046.

9.

The differentiated airway epithelium infected by influenza viruses maintains the barrier function despite a dramatic loss of ciliated cells.

Wu NH, Yang W, Beineke A, Dijkman R, Matrosovich M, Baumgärtner W, Thiel V, Valentin-Weigand P, Meng F, Herrler G.

Sci Rep. 2016 Dec 22;6:39668. doi: 10.1038/srep39668.

10.

Link of a ubiquitous human coronavirus to dromedary camels.

Corman VM, Eckerle I, Memish ZA, Liljander AM, Dijkman R, Jonsdottir H, Juma Ngeiywa KJ, Kamau E, Younan M, Al Masri M, Assiri A, Gluecks I, Musa BE, Meyer B, Müller MA, Hilali M, Bornstein S, Wernery U, Thiel V, Jores J, Drexler JF, Drosten C.

Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):9864-9. doi: 10.1073/pnas.1604472113. Epub 2016 Aug 15.

11.

Coronaviruses and the human airway: a universal system for virus-host interaction studies.

Jonsdottir HR, Dijkman R.

Virol J. 2016 Feb 6;13:24. doi: 10.1186/s12985-016-0479-5. Review.

12.

First international external quality assessment of molecular diagnostics for Mers-CoV.

Pas SD, Patel P, Reusken C, Domingo C, Corman VM, Drosten C, Dijkman R, Thiel V, Nowotny N, Koopmans MP, Niedrig M.

J Clin Virol. 2015 Aug;69:81-5. doi: 10.1016/j.jcv.2015.05.022. Epub 2015 May 30.

13.

Characterization of human coronaviruses on well-differentiated human airway epithelial cell cultures.

Jonsdottir HR, Dijkman R.

Methods Mol Biol. 2015;1282:73-87. doi: 10.1007/978-1-4939-2438-7_8.

PMID:
25720473
14.

Culturing of respiratory viruses in well-differentiated pseudostratified human airway epithelium as a tool to detect unknown viruses.

Farsani SM, Deijs M, Dijkman R, Molenkamp R, Jeeninga RE, Ieven M, Goossens H, van der Hoek L.

Influenza Other Respir Viruses. 2015 Jan;9(1):51-7. doi: 10.1111/irv.12297. Epub 2014 Dec 8.

15.

Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus.

Lundin A, Dijkman R, Bergström T, Kann N, Adamiak B, Hannoun C, Kindler E, Jónsdóttir HR, Muth D, Kint J, Forlenza M, Müller MA, Drosten C, Thiel V, Trybala E.

PLoS Pathog. 2014 May 29;10(5):e1004166. doi: 10.1371/journal.ppat.1004166. eCollection 2014 May.

16.

Interferon lambda 4 signals via the IFNλ receptor to regulate antiviral activity against HCV and coronaviruses.

Hamming OJ, Terczyńska-Dyla E, Vieyres G, Dijkman R, Jørgensen SE, Akhtar H, Siupka P, Pietschmann T, Thiel V, Hartmann R.

EMBO J. 2013 Nov 27;32(23):3055-65. doi: 10.1038/emboj.2013.232. Epub 2013 Oct 29.

17.

Emergence of a C-terminal seven-amino-acid elongation of NS1 in around 1950 conferred a minor growth advantage to former seasonal influenza A viruses.

Lohrmann F, Dijkman R, Stertz S, Thiel V, Haller O, Staeheli P, Kochs G.

J Virol. 2013 Oct;87(20):11300-3. doi: 10.1128/JVI.01271-13. Epub 2013 Aug 7.

18.

TMPRSS2 activates the human coronavirus 229E for cathepsin-independent host cell entry and is expressed in viral target cells in the respiratory epithelium.

Bertram S, Dijkman R, Habjan M, Heurich A, Gierer S, Glowacka I, Welsch K, Winkler M, Schneider H, Hofmann-Winkler H, Thiel V, Pöhlmann S.

J Virol. 2013 Jun;87(11):6150-60. doi: 10.1128/JVI.03372-12. Epub 2013 Mar 27.

19.

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC.

Raj VS, Mou H, Smits SL, Dekkers DH, Müller MA, Dijkman R, Muth D, Demmers JA, Zaki A, Fouchier RA, Thiel V, Drosten C, Rottier PJ, Osterhaus AD, Bosch BJ, Haagmans BL.

Nature. 2013 Mar 14;495(7440):251-4. doi: 10.1038/nature12005.

PMID:
23486063
20.

Isolation and characterization of current human coronavirus strains in primary human epithelial cell cultures reveal differences in target cell tropism.

Dijkman R, Jebbink MF, Koekkoek SM, Deijs M, Jónsdóttir HR, Molenkamp R, Ieven M, Goossens H, Thiel V, van der Hoek L.

J Virol. 2013 Jun;87(11):6081-90. doi: 10.1128/JVI.03368-12. Epub 2013 Feb 20.

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