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Absolute Quantification of Noncoding RNA by Microscale Thermophoresis.

Jacob D, Thüring K, Galliot A, Marchand V, Galvanin A, Ciftci A, Scharmann K, Stock M, Roignant JY, Leidel SA, Motorin Y, Schaffrath R, Klassen R, Helm M.

Angew Chem Int Ed Engl. 2019 Mar 20. doi: 10.1002/anie.201814377. [Epub ahead of print]


Roles of Elongator Dependent tRNA Modification Pathways in Neurodegeneration and Cancer.

Hawer H, Hammermeister A, Ravichandran KE, Glatt S, Schaffrath R, Klassen R.

Genes (Basel). 2018 Dec 28;10(1). pii: E19. doi: 10.3390/genes10010019. Review.


Unfolded Protein Response Suppression in Yeast by Loss of tRNA Modifications.

Bruch A, Klassen R, Schaffrath R.

Genes (Basel). 2018 Oct 23;9(11). pii: E516. doi: 10.3390/genes9110516.


Collaboration of tRNA modifications and elongation factor eEF1A in decoding and nonsense suppression.

Klassen R, Schaffrath R.

Sci Rep. 2018 Aug 24;8(1):12749. doi: 10.1038/s41598-018-31158-2.


Protein Phosphatase Sit4 Affects Lipid Droplet Synthesis and Soraphen A Resistance Independent of Its Role in Regulating Elongator Dependent tRNA Modification.

Bozaquel-Morais BL, Vogt L, D'Angelo V, Schaffrath R, Klassen R, Montero-Lomelí M.

Biomolecules. 2018 Jul 11;8(3). pii: E49. doi: 10.3390/biom8030049.


Cooperativity between different tRNA modifications and their modification pathways.

Sokołowski M, Klassen R, Bruch A, Schaffrath R, Glatt S.

Biochim Biophys Acta Gene Regul Mech. 2018 Apr;1861(4):409-418. doi: 10.1016/j.bbagrm.2017.12.003. Epub 2017 Dec 5. Review.


Sulfur transfer and activation by ubiquitin-like modifier system Uba4•Urm1 link protein urmylation and tRNA thiolation in yeast.

Jüdes A, Bruch A, Klassen R, Helm M, Schaffrath R.

Microb Cell. 2016 Oct 24;3(11):554-564. doi: 10.15698/mic2016.11.539.


Combined tRNA modification defects impair protein homeostasis and synthesis of the yeast prion protein Rnq1.

Schaffrath R, Klassen R.

Prion. 2017 Jan 2;11(1):48-53. doi: 10.1080/19336896.2017.1284734.


Role of Pseudouridine Formation by Deg1 for Functionality of Two Glutamine Isoacceptor tRNAs.

Klassen R, Schaffrath R.

Biomolecules. 2017 Jan 26;7(1). pii: E8. doi: 10.3390/biom7010008.


Independent suppression of ribosomal +1 frameshifts by different tRNA anticodon loop modifications.

Klassen R, Bruch A, Schaffrath R.

RNA Biol. 2017 Sep 2;14(9):1252-1259. doi: 10.1080/15476286.2016.1267098. Epub 2016 Dec 12.


Glutaredoxin GRXS17 Associates with the Cytosolic Iron-Sulfur Cluster Assembly Pathway.

Iñigo S, Durand AN, Ritter A, Le Gall S, Termathe M, Klassen R, Tohge T, De Coninck B, Van Leene J, De Clercq R, Cammue BP, Fernie AR, Gevaert K, De Jaeger G, Leidel SA, Schaffrath R, Van Lijsebettens M, Pauwels L, Goossens A.

Plant Physiol. 2016 Oct;172(2):858-873. Epub 2016 Aug 8.


tRNA anticodon loop modifications ensure protein homeostasis and cell morphogenesis in yeast.

Klassen R, Ciftci A, Funk J, Bruch A, Butter F, Schaffrath R.

Nucleic Acids Res. 2016 Dec 15;44(22):10946-10959. Epub 2016 Aug 5.


DNA Damage Responses Are Induced by tRNA Anticodon Nucleases and Hygromycin B.

Wemhoff S, Klassen R, Beetz A, Meinhardt F.

PLoS One. 2016 Jul 29;11(7):e0157611. doi: 10.1371/journal.pone.0157611. eCollection 2016.


Response to Burgers et al.

Johnson RE, Klassen R, Prakash L, Prakash S.

Mol Cell. 2016 Feb 18;61(4):494-495. doi: 10.1016/j.molcel.2016.01.018. No abstract available.


DNA damage induced by the anticodon nuclease from a Pichia acaciae killer strain is linked to ribonucleotide reductase depletion.

Wemhoff S, Klassen R, Meinhardt F.

Cell Microbiol. 2016 Feb;18(2):211-22. doi: 10.1111/cmi.12496. Epub 2015 Aug 31.


A Major Role of DNA Polymerase δ in Replication of Both the Leading and Lagging DNA Strands.

Johnson RE, Klassen R, Prakash L, Prakash S.

Mol Cell. 2015 Jul 16;59(2):163-175. doi: 10.1016/j.molcel.2015.05.038. Epub 2015 Jul 2.


Autoselection of cytoplasmic yeast virus like elements encoding toxin/antitoxin systems involves a nuclear barrier for immunity gene expression.

Kast A, Voges R, Schroth M, Schaffrath R, Klassen R, Meinhardt F.

PLoS Genet. 2015 May 14;11(5):e1005005. doi: 10.1371/journal.pgen.1005005. eCollection 2015 May.


Urmylation and tRNA thiolation functions of ubiquitin-like Uba4·Urm1 systems are conserved from yeast to man.

Jüdes A, Ebert F, Bär C, Thüring KL, Harrer A, Klassen R, Helm M, Stark MJ, Schaffrath R.

FEBS Lett. 2015 Apr 2;589(8):904-9. doi: 10.1016/j.febslet.2015.02.024. Epub 2015 Mar 3.


Loss of anticodon wobble uridine modifications affects tRNA(Lys) function and protein levels in Saccharomyces cerevisiae.

Klassen R, Grunewald P, Thüring KL, Eichler C, Helm M, Schaffrath R.

PLoS One. 2015 Mar 6;10(3):e0119261. doi: 10.1371/journal.pone.0119261. eCollection 2015.


Loss of wobble uridine modification in tRNA anticodons interferes with TOR pathway signaling.

Scheidt V, Jüdes A, Bär C, Klassen R, Schaffrath R.

Microb Cell. 2014 Nov 29;1(12):416-424. doi: 10.15698/mic2014.12.179.

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