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Items: 1 to 20 of 49

1.

Characterization of Human Induced Pluripotent Stem Cell-Derived Hepatocytes with Mature Features and Potential for Modeling Metabolic Diseases.

Holmgren G, Ulfenborg B, Asplund A, Toet K, Andersson CX, Hammarstedt A, Hanemaaijer R, Küppers-Munther B, Synnergren J.

Int J Mol Sci. 2020 Jan 11;21(2). pii: E469. doi: 10.3390/ijms21020469.

2.

Obeticholic Acid Modulates Serum Metabolites and Gene Signatures Characteristic of Human NASH and Attenuates Inflammation and Fibrosis Progression in Ldlr-/-.Leiden Mice.

Morrison MC, Verschuren L, Salic K, Verheij J, Menke A, Wielinga PY, Iruarrizaga-Lejarreta M, Gole L, Yu WM, Turner S, Caspers MPM, Martínez-Arranz I, Pieterman E, Stoop R, van Koppen A, van den Hoek AM, Mato JM, Hanemaaijer R, Alonso C, Kleemann R.

Hepatol Commun. 2018 Oct 29;2(12):1513-1532. doi: 10.1002/hep4.1270. eCollection 2018 Dec.

3.

Key Inflammatory Processes in Human NASH Are Reflected in Ldlr-/-.Leiden Mice: A Translational Gene Profiling Study.

Morrison MC, Kleemann R, van Koppen A, Hanemaaijer R, Verschuren L.

Front Physiol. 2018 Feb 23;9:132. doi: 10.3389/fphys.2018.00132. eCollection 2018.

4.

Uncovering a Predictive Molecular Signature for the Onset of NASH-Related Fibrosis in a Translational NASH Mouse Model.

van Koppen A, Verschuren L, van den Hoek AM, Verheij J, Morrison MC, Li K, Nagabukuro H, Costessi A, Caspers MPM, van den Broek TJ, Sagartz J, Kluft C, Beysen C, Emson C, van Gool AJ, Goldschmeding R, Stoop R, Bobeldijk-Pastorova I, Turner SM, Hanauer G, Hanemaaijer R.

Cell Mol Gastroenterol Hepatol. 2017 Oct 14;5(1):83-98.e10. doi: 10.1016/j.jcmgh.2017.10.001. eCollection 2018.

5.

The composition of collagen in the aneurysm wall of men and women.

Villard C, Eriksson P, Hanemaaijer R, Lindeman JH, Hultgren R.

J Vasc Surg. 2017 Aug;66(2):579-585.e1. doi: 10.1016/j.jvs.2016.02.056. Epub 2016 May 24.

6.

Matrix cross-linking lysyl oxidases are induced in response to myocardial infarction and promote cardiac dysfunction.

González-Santamaría J, Villalba M, Busnadiego O, López-Olañeta MM, Sandoval P, Snabel J, López-Cabrera M, Erler JT, Hanemaaijer R, Lara-Pezzi E, Rodríguez-Pascual F.

Cardiovasc Res. 2016 Jan 1;109(1):67-78. doi: 10.1093/cvr/cvv214. Epub 2015 Aug 10.

PMID:
26260798
7.

Extracellular matrix proteins: a positive feedback loop in lung fibrosis?

Blaauboer ME, Boeijen FR, Emson CL, Turner SM, Zandieh-Doulabi B, Hanemaaijer R, Smit TH, Stoop R, Everts V.

Matrix Biol. 2014 Feb;34:170-8. doi: 10.1016/j.matbio.2013.11.002. Epub 2013 Nov 27.

8.

Stimulation of fibrotic processes by the infrapatellar fat pad in cultured synoviocytes from patients with osteoarthritis: a possible role for prostaglandin f2α.

Bastiaansen-Jenniskens YM, Wei W, Feijt C, Waarsing JH, Verhaar JA, Zuurmond AM, Hanemaaijer R, Stoop R, van Osch GJ.

Arthritis Rheum. 2013 Aug;65(8):2070-80. doi: 10.1002/art.37996.

9.

Novel combination of collagen dynamics analysis and transcriptional profiling reveals fibrosis-relevant genes and pathways.

Blaauboer ME, Emson CL, Verschuren L, van Erk M, Turner SM, Everts V, Hanemaaijer R, Stoop R.

Matrix Biol. 2013 Oct-Nov;32(7-8):424-31. doi: 10.1016/j.matbio.2013.04.005. Epub 2013 May 3.

PMID:
23648810
10.

Role of caveolin-1 in fibrotic diseases.

Gvaramia D, Blaauboer ME, Hanemaaijer R, Everts V.

Matrix Biol. 2013 Aug 8;32(6):307-15. doi: 10.1016/j.matbio.2013.03.005. Epub 2013 Apr 11. Review.

11.

Identification of free nitric oxide radicals in rat bone marrow: implications for progenitor cell mobilization in hypertension.

Aleksinskaya MA, van Faassen EE, Nelissen J, Janssen BJ, De Mey JG, Hanemaaijer R, Rabelink T, van Zonneveld AJ.

PLoS One. 2013;8(3):e57761. doi: 10.1371/journal.pone.0057761. Epub 2013 Mar 12.

12.

Impaired collagen biosynthesis and cross-linking in aorta of patients with bicuspid aortic valve.

Wågsäter D, Paloschi V, Hanemaaijer R, Hultenby K, Bank RA, Franco-Cereceda A, Lindeman JH, Eriksson P.

J Am Heart Assoc. 2013 Feb 14;2(1):e000034. doi: 10.1161/JAHA.112.000034.

13.

A clinical evaluation of statin pleiotropy: statins selectively and dose-dependently reduce vascular inflammation.

van der Meij E, Koning GG, Vriens PW, Peeters MF, Meijer CA, Kortekaas KE, Dalman RL, van Bockel JH, Hanemaaijer R, Kooistra T, Kleemann R, Lindeman JH.

PLoS One. 2013;8(1):e53882. doi: 10.1371/journal.pone.0053882. Epub 2013 Jan 22.

14.

Cyclic mechanical stretch reduces myofibroblast differentiation of primary lung fibroblasts.

Blaauboer ME, Smit TH, Hanemaaijer R, Stoop R, Everts V.

Biochem Biophys Res Commun. 2011 Jan 7;404(1):23-7. doi: 10.1016/j.bbrc.2010.11.033. Epub 2010 Nov 20.

15.

Matrix metalloproteinase-9 measured in urine from bladder cancer patients is an independent prognostic marker of poor survival.

Offersen BV, Knap MM, Horsman MR, Verheijen J, Hanemaaijer R, Overgaard J.

Acta Oncol. 2010 Nov;49(8):1283-7. doi: 10.3109/0284186X.2010.509109. Epub 2010 Sep 15.

PMID:
20843171
16.

The pathophysiology of abdominal aortic aneurysm growth: corresponding and discordant inflammatory and proteolytic processes in abdominal aortic and popliteal artery aneurysms.

Abdul-Hussien H, Hanemaaijer R, Kleemann R, Verhaaren BF, van Bockel JH, Lindeman JH.

J Vasc Surg. 2010 Jun;51(6):1479-87. doi: 10.1016/j.jvs.2010.01.057.

17.

Urinary matrix metalloproteinase-8 and -9 activities in type 2 diabetic subjects: A marker of incipient diabetic nephropathy?

van der Zijl NJ, Hanemaaijer R, Tushuizen ME, Schindhelm RK, Boerop J, Rustemeijer C, Bilo HJ, Verheijen JH, Diamant M.

Clin Biochem. 2010 May;43(7-8):635-9. doi: 10.1016/j.clinbiochem.2010.02.006. Epub 2010 Feb 23.

PMID:
20184870
18.

Doxycycline therapy for abdominal aneurysm: Improved proteolytic balance through reduced neutrophil content.

Abdul-Hussien H, Hanemaaijer R, Verheijen JH, van Bockel JH, Geelkerken RH, Lindeman JH.

J Vasc Surg. 2009 Mar;49(3):741-9. doi: 10.1016/j.jvs.2008.09.055.

19.

Erosive arthritis in a patient with pycnodysostosis: an experiment of nature.

Ainola M, Valleala H, Nykänen P, Risteli J, Hanemaaijer R, Konttinen YT.

Arthritis Rheum. 2008 Nov;58(11):3394-401. doi: 10.1002/art.23996.

20.

Straining mode-dependent collagen remodeling in engineered cardiovascular tissue.

Rubbens MP, Mol A, van Marion MH, Hanemaaijer R, Bank RA, Baaijens FP, Bouten CV.

Tissue Eng Part A. 2009 Apr;15(4):841-9. doi: 10.1089/ten.tea.2008.0185.

PMID:
18847358

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