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Rev Esp Cardiol. 2009 Mar;62(3):323-7.

Effect of statin treatment on mortality in a large cohort of heart failure patients.

[Article in English, Spanish]

Collaborators (107)

Barrio PD, Barrio EE, López EB, Garri FS, Payá VC, Rubiera JA, Alcaide AR, García GC, Martínez de la Concha L, Roses JL, Rodríguez TP, Novales JA, Méndez S, Galve E, de Miguel MA, López Gómez D, Sáenz L, Alvarez A, Hidalgo DR, Dacosta JA, Monguell ER, Beange AC, Abaurrea FR, Serra CM, Eizagaechaverria NM, Serret IL, de la Concepción Palomino C, Ramos YP, Torrent JL, Bellver AN, Sánchez MA, Pineda SO, García de Burgos y de Rico F, Torrent AJ, Otegui JZ, Arruti AS, Fernández PO, Nelisen CL, Baun O, Pereira JL, Morer SM, Guitard R, Machuca JC, García-Arboleya Puerto F, Lorite NM, Kaplinsky E, Fernández JB, Montes MM, González Maqueda I, Guzmán Martín G, Rangel LS, Fernández FA, Rodrigo AI, Grande Ruiz A, Fernández Escribano M, González Cocina E, Calvo FT, de Mora Martín M, Pérez Ruiz JM, de Teresa Galván E, Campos EM, Jiménez Navarro M, del Vigo ER, Arrillaga NG, Pérez de Juan MA, de Toro Santos M, Díaz Molina B, Rodríguez Lambert JL, Escribano FL, Gutiérrez Alemany J, Sánchez JP, Cortés FM, Molina OP, Sánchez Fernández PL, Herrero FM, Iraola RQ, Sánchez Haya E, Fernández JR, González Juanatey JR, Gómez Otero I, Beltrán Rodríguez JC, Torres LP, Martínez Martínez A, Ruiz AB, de Castro Aritmediz R, Sayrol LC, Giménez JC, Padrón AL, Rodríguez FM, Velasco Rami JA, Soriano FR, Almenar L, Soriano JR, Toral BS, Salvador Sanz A, Llácer A, Muñoz J, de la Fuente Galán L, Iglesias FC, Arias JL, Borau FA, del Río Lligorit A, San Pedro Feliú A, Sanz Julve M, Peiró TB, Lázaro I, José Ramírez M.

Author information

1
Sección de Cardiología, Hospital General de Elche, Elche, 03007 Alicante, Spain. ajordant@coma.es

Abstract

We studied 3162 heart failure patients included in the Spanish BADAPIC registry in order to determine whether statin treatment influences prognosis. Patients were followed up for 35 +/- 22 months (median, 32 months). Patients on statins were more often male and had higher prevalences of risk factors, ischemic heart disease and systolic dysfunction (P< .001) than those not on statins. After adjustment for age, risk factors, ischemic heart disease, renal failure, ejection fraction, anemia, heart rate and drug treatment, statin treatment was found to be a favorable independent predictor of survival: the hazard ratio for mortality was 0.73 (95% confidence interval, 0.45-0.88; P< .001). During follow-up, the 3-year survival rate was higher in patients treated with statins (75% vs. 68%; P< .001). In patients with heart failure, statin treatment appears to be independently associated with better survival.

PMID:
19268080
[Indexed for MEDLINE]
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