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Items: 1 to 20 of 74

1.

New chalcone-sulfonamide hybrids exhibiting anticancer and antituberculosis activity.

Castaño LF, Cuartas V, Bernal A, Insuasty A, Guzman J, Vidal O, Rubio V, Puerto G, Lukáč P, Vimberg V, Balíková-Novtoná G, Vannucci L, Janata J, Quiroga J, Abonia R, Nogueras M, Cobo J, Insuasty B.

Eur J Med Chem. 2019 Aug 15;176:50-60. doi: 10.1016/j.ejmech.2019.05.013. Epub 2019 May 7.

PMID:
31096118
2.

Catalyst-free assembly of giant tris(heteroaryl)methanes: synthesis of novel pharmacophoric triads and model sterically crowded tris(heteroaryl/aryl)methyl cation salts.

Abonia R, Gutiérrez LF, Insuasty B, Quiroga J, Laali KK, Zhao C, Borosky GL, Horwitz SM, Bunge SD.

Beilstein J Org Chem. 2019 Mar 12;15:642-654. doi: 10.3762/bjoc.15.60. eCollection 2019.

3.

Anti-inflammatory activity of triazine derivatives: A systematic review.

Marín-Ocampo L, Veloza LA, Abonia R, Sepúlveda-Arias JC.

Eur J Med Chem. 2019 Jan 15;162:435-447. doi: 10.1016/j.ejmech.2018.11.027. Epub 2018 Nov 13.

PMID:
30469039
4.

Synthesis of New 1,3,5-Triazine-Based 2-Pyrazolines as Potential Anticancer Agents.

Moreno LM, Quiroga J, Abonia R, Ramírez-Prada J, Insuasty B.

Molecules. 2018 Aug 6;23(8). pii: E1956. doi: 10.3390/molecules23081956.

5.

Design of Two Alternative Routes for the Synthesis of Naftifine and Analogues as Potential Antifungal Agents.

Abonia R, Garay A, Castillo JC, Insuasty B, Quiroga J, Nogueras M, Cobo J, Butassi E, Zacchino S.

Molecules. 2018 Feb 26;23(3). pii: E520. doi: 10.3390/molecules23030520.

6.

In Silico and in Vitro-Guided Identification of Inhibitors of Alkylquinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa.

Soukarieh F, Vico Oton E, Dubern JF, Gomes J, Halliday N, de Pilar Crespo M, Ramírez-Prada J, Insuasty B, Abonia R, Quiroga J, Heeb S, Williams P, Stocks MJ, Cámara M.

Molecules. 2018 Jan 28;23(2). pii: E257. doi: 10.3390/molecules23020257.

7.

Synthesis and DFT Calculations of Novel Vanillin-Chalcones and Their 3-Aryl-5-(4-(2-(dimethylamino)-ethoxy)-3-methoxyphenyl)-4,5-dihydro-1H-pyrazole-1-carbaldehyde Derivatives as Antifungal Agents.

Illicachi LA, Montalvo-Acosta JJ, Insuasty A, Quiroga J, Abonia R, Sortino M, Zacchino S, Insuasty B.

Molecules. 2017 Sep 5;22(9). pii: E1476. doi: 10.3390/molecules22091476.

8.

Design, synthesis and crystallographic study of novel indole-based cyano derivatives as key building blocks for heteropolycyclic compounds of major complexity.

García AC, Abonía R, Jaramillo-Gómez LM, Cobo J, Glidewell C.

Acta Crystallogr C Struct Chem. 2017 Dec 1;73(Pt 12):1040-1049. doi: 10.1107/S2053229617015789. Epub 2017 Nov 8.

PMID:
29206113
9.

A Schmidt rearrangement-mediated synthesis of novel tetrahydro-benzo[1,4]diazepin-5-ones as potential anticancer and antiprotozoal agents.

Insuasty D, Robledo SM, Vélez ID, Cuervo P, Insuasty B, Quiroga J, Nogueras M, Cobo J, Abonia R.

Eur J Med Chem. 2017 Dec 1;141:567-583. doi: 10.1016/j.ejmech.2017.10.024. Epub 2017 Oct 10.

PMID:
29102177
10.

Synthesis of novel 7-aryl and 7-spiropyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine derivatives and their study as AChE inhibitors.

Acosta P, Insuasty B, Abonia R, Gutierrez M, Quiroga J.

Mol Divers. 2017 Nov;21(4):943-955. doi: 10.1007/s11030-017-9774-3. Epub 2017 Aug 7.

PMID:
28785929
11.

Microwave-Assisted Synthesis of Diversely Substituted Quinoline-Based Dihydropyridopyrimidine and Dihydropyrazolopyridine Hybrids.

Insuasty D, Abonia R, Insuasty B, Quiroga J, Laali KK, Nogueras M, Cobo J.

ACS Comb Sci. 2017 Aug 14;19(8):555-563. doi: 10.1021/acscombsci.7b00091. Epub 2017 Jul 26.

PMID:
28723092
12.

Synthesis of novel quinoline-based 4,5-dihydro-1H-pyrazoles as potential anticancer, antifungal, antibacterial and antiprotozoal agents.

Ramírez-Prada J, Robledo SM, Vélez ID, Crespo MDP, Quiroga J, Abonia R, Montoya A, Svetaz L, Zacchino S, Insuasty B.

Eur J Med Chem. 2017 May 5;131:237-254. doi: 10.1016/j.ejmech.2017.03.016. Epub 2017 Mar 16.

PMID:
28329730
13.

Synthesis and Antifungal in Vitro Evaluation of Pyrazolo[3,4-b]pyridines Derivatives Obtained by Aza-Diels-Alder Reaction and Microwave Irradiation.

Quiroga J, Villarreal Y, Gálvez J, Ortíz A, Insuasty B, Abonia R, Raimondi M, Zacchino S.

Chem Pharm Bull (Tokyo). 2017 Feb 1;65(2):143-150. doi: 10.1248/cpb.c16-00652. Epub 2016 Nov 25.

14.

Hybrid Molecules Containing a 7-Chloro-4-aminoquinoline Nucleus and a Substituted 2-Pyrazoline with Antiproliferative and Antifungal Activity.

Montoya A, Quiroga J, Abonia R, Derita M, Sortino M, Ornelas A, Zacchino S, Insuasty B.

Molecules. 2016 Jul 27;21(8). pii: E969. doi: 10.3390/molecules21080969.

15.

Pseudo-Multicomponent Reactions of Arynes with N-Aryl Imines.

Castillo JC, Quiroga J, Abonia R, Rodriguez J, Coquerel Y.

J Org Chem. 2015 Oct 2;80(19):9767-73. doi: 10.1021/acs.joc.5b01564. Epub 2015 Sep 30.

PMID:
26340342
16.

The Aryne aza-Diels-Alder Reaction: Flexible Syntheses of Isoquinolines.

Castillo JC, Quiroga J, Abonia R, Rodriguez J, Coquerel Y.

Org Lett. 2015 Jul 2;17(13):3374-7. doi: 10.1021/acs.orglett.5b01704. Epub 2015 Jun 18.

PMID:
26086988
17.

Microwave-Assisted Synthesis of Novel Pyrazolo[3,4-g][1,8]naphthyridin-5-amine with Potential Antifungal and Antitumor Activity.

Acosta P, Butassi E, Insuasty B, Ortiz A, Abonia R, Zacchino SA, Quiroga J.

Molecules. 2015 May 12;20(5):8499-520. doi: 10.3390/molecules20058499.

18.

An efficient synthesis of new caffeine-based chalcones, pyrazolines and pyrazolo[3,4-b][1,4]diazepines as potential antimalarial, antitrypanosomal and antileishmanial agents.

Insuasty B, Ramírez J, Becerra D, Echeverry C, Quiroga J, Abonia R, Robledo SM, Vélez ID, Upegui Y, Muñoz JA, Ospina V, Nogueras M, Cobo J.

Eur J Med Chem. 2015 Mar 26;93:401-13. doi: 10.1016/j.ejmech.2015.02.040. Epub 2015 Feb 21.

PMID:
25725376
19.

Synthesis of novel thiazole-based 8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepines as potential antitumor and antifungal agents.

Ramírez J, Svetaz L, Quiroga J, Abonia R, Raimondi M, Zacchino S, Insuasty B.

Eur J Med Chem. 2015 Mar 6;92:866-75. doi: 10.1016/j.ejmech.2015.01.053. Epub 2015 Jan 26.

PMID:
25638570
20.

Crystal structure of (±)-3-[(benzo[d][1,3]dioxol-5-yl)meth-yl]-2-(3,4,5-tri-meth-oxy-phen-yl)-1,3-thia-zolidin-4-one.

Moreno-Fuquen R, Castillo JC, Abonia R, Ellena J, De Simone CA.

Acta Crystallogr Sect E Struct Rep Online. 2014 Nov 5;70(Pt 12):o1235-6. doi: 10.1107/S160053681402340X. eCollection 2014 Dec 1.

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