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Hexagonal Mesoporous Silica as a Rapid, Efficient and Versatile Tool for MALDI-TOF MS Sample Preparation in Clinical Peptidomics Analysis: A Pilot Study.

Terracciano R, Preianò M, Maggisano G, Pelaia C, Savino R.

Molecules. 2019 Jun 22;24(12). pii: E2311. doi: 10.3390/molecules24122311.


Rapid Detection and Identification of Antimicrobial Peptide Fingerprints of Nasal Fluid by Mesoporous Silica Particles and MALDI-TOF/TOF Mass Spectrometry: From the Analytical Approach to the Diagnostic Applicability in Precision Medicine.

Preianò M, Maggisano G, Murfuni MS, Villella C, Colica C, Fregola A, Pelaia C, Lombardo N, Pelaia G, Savino R, Terracciano R.

Int J Mol Sci. 2018 Dec 12;19(12). pii: E4005. doi: 10.3390/ijms19124005.


Omalizumab lowers asthma exacerbations, oral corticosteroid intake and blood eosinophils: Results of a 5-YEAR single-centre observational study.

Pelaia C, Calabrese C, Barbuto S, Busceti MT, Preianò M, Gallelli L, Savino R, Vatrella A, Pelaia G.

Pulm Pharmacol Ther. 2019 Feb;54:25-30. doi: 10.1016/j.pupt.2018.11.002. Epub 2018 Nov 7.


TLR4 triggered complex inflammation in human pancreatic islets.

He W, Rebello O, Savino R, Terracciano R, Schuster-Klein C, Guardiola B, Maedler K.

Biochim Biophys Acta Mol Basis Dis. 2019 Jan;1865(1):86-97. doi: 10.1016/j.bbadis.2018.09.030. Epub 2018 Oct 1.


An Analytical Method for Assessing Optimal Storage Conditions of Gingival Crevicular Fluid and Disclosing a Peptide Biomarker Signature of Gingivitis by MALDI-TOF MS.

Preianò M, Maggisano G, Murfuni MS, Villella C, Pelaia C, Montalcini T, Lombardo N, Pelaia G, Savino R, Terracciano R.

Proteomics Clin Appl. 2018 Sep;12(5):e1800005. doi: 10.1002/prca.201800005. Epub 2018 Apr 23.


Severe eosinophilic asthma: from the pathogenic role of interleukin-5 to the therapeutic action of mepolizumab.

Pelaia C, Vatrella A, Busceti MT, Gallelli L, Terracciano R, Savino R, Pelaia G.

Drug Des Devel Ther. 2017 Oct 30;11:3137-3144. doi: 10.2147/DDDT.S150656. eCollection 2017. Review.


Biological mechanisms underlying the clinical effects of allergen-specific immunotherapy in asthmatic children.

Pelaia C, Vatrella A, Lombardo N, Terracciano R, Navalesi P, Savino R, Pelaia G.

Expert Opin Biol Ther. 2018 Feb;18(2):197-204. doi: 10.1080/14712598.2018.1402003. Epub 2017 Nov 8. Review.


Objective and self-evaluation voice analysis after transoral laser cordectomy and radiotherapy in T1a-T1b glottic cancer.

Lombardo N, Aragona T, Alsayyad S, Pelaia G, Terracciano R, Savino R.

Lasers Med Sci. 2018 Jan;33(1):141-147. doi: 10.1007/s10103-017-2361-0. Epub 2017 Oct 26.


Theophylline action on primary human bronchial epithelial cells under proinflammatory stimuli and steroidal drugs: a therapeutic rationale approach.

Gallelli L, Falcone D, Cannataro R, Perri M, Serra R, Pelaia G, Maselli R, Savino R, Spaziano G, D'Agostino B.

Drug Des Devel Ther. 2017 Jan 23;11:265-272. doi: 10.2147/DDDT.S118485. eCollection 2017.


A rapid differential display analysis of nasal swab fingerprints to distinguish allergic from non-allergic rhinitis subjects by mesoporous silica particles and MALDI-TOF mass spectrometry.

Lombardo N, Preianò M, Maggisano G, Murfuni MS, Messina L, Pelaia G, Savino R, Terracciano R.

Proteomics. 2017 Mar;17(6). doi: 10.1002/pmic.201600215. Epub 2017 Feb 8.


Targeted proteomic approach in prostatic tissue: a panel of potential biomarkers for cancer detection.

Aiello D, Casadonte F, Terracciano R, Damiano R, Savino R, Sindona G, Napoli A.

Oncoscience. 2016 Jul 8;3(7-8):220-241. doi: 10.18632/oncoscience.313. eCollection 2016.


Influence of storage conditions on MALDI-TOF MS profiling of gingival crevicular fluid: Implications on the role of S100A8 and S100A9 for clinical and proteomic based diagnostic investigations.

Preianò M, Maggisano G, Lombardo N, Montalcini T, Paduano S, Pelaia G, Savino R, Terracciano R.

Proteomics. 2016 Mar;16(6):1033-45. doi: 10.1002/pmic.201500328.


Asthma and COPD proteomics: current approaches and future directions.

Terracciano R, Pelaia G, Preianò M, Savino R.

Proteomics Clin Appl. 2015 Feb;9(1-2):203-20. doi: 10.1002/prca.201400099. Epub 2015 Jan 23. Review.


Effects of simvastatin on cell viability and proinflammatory pathways in lung adenocarcinoma cells exposed to hydrogen peroxide.

Gallelli L, Falcone D, Scaramuzzino M, Pelaia G, D'Agostino B, Mesuraca M, Terracciano R, Spaziano G, Maselli R, Navarra M, Savino R.

BMC Pharmacol Toxicol. 2014 Nov 29;15:67. doi: 10.1186/2050-6511-15-67.


Assessment of pre-analytical and analytical variables affecting peptidome profiling of gingival crevicular fluid by MALDI-TOF mass spectrometry.

Preianò M, Falcone D, Maggisano G, Montalcini T, Navarra M, Paduano S, Savino R, Terracciano R.

Clin Chim Acta. 2014 Nov 1;437:120-8. doi: 10.1016/j.cca.2014.07.022. Epub 2014 Jul 25.


Application of proteomics and peptidomics to COPD.

Pelaia G, Terracciano R, Vatrella A, Gallelli L, Busceti MT, Calabrese C, Stellato C, Savino R, Maselli R.

Biomed Res Int. 2014;2014:764581. doi: 10.1155/2014/764581. Epub 2014 May 5. Review.


Association between low bone mineral density and increased α-defensin in salivary fluid among postmenopausal women.

Terracciano R, Migliaccio V, Savino R, Pujia A, Montalcini T.

Menopause. 2013 Dec;20(12):1275-9. doi: 10.1097/GME.0b013e31829e4055.


Effects of ambrisentan in a patient affected by combined pulmonary fibrosis and emphysema and by severe pulmonary hypertension: clinical, functional, and biomolecular findings.

Roccia F, Campolo B, Gallelli L, Spaccarotella C, Mongiardo A, Falcone D, Savino R, Pelaia G, Indolfi C, Maselli R.

Clin Drug Investig. 2013 Jun;33(6):451-7. doi: 10.1007/s40261-013-0083-z.


The proteomics big challenge for biomarkers and new drug-targets discovery.

Savino R, Paduano S, Preianò M, Terracciano R.

Int J Mol Sci. 2012 Oct 29;13(11):13926-48. doi: 10.3390/ijms131113926. Review.


Simultaneous extraction and rapid visualization of peptidomic and lipidomic body fluids fingerprints using mesoporous aluminosilicate and MALDI-TOF MS.

Preianò M, Pasqua L, Gallelli L, Galasso O, Gasparini G, Savino R, Terracciano R.

Proteomics. 2012 Nov;12(22):3286-94. doi: 10.1002/pmic.201200204. Epub 2012 Oct 19.


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