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Items: 1 to 20 of 289


High Levels of Apoptosis Are Induced in the Human Colon Cancer HT-29 Cell Line by Co-Administration of Sulforaphane and a Peptide Nucleic Acid Targeting miR-15b-5p.

Gasparello J, Gambari L, Papi C, Rozzi A, Manicardi A, Corradini R, Gambari R, Finotti A.

Nucleic Acid Ther. 2020 Feb 17. doi: 10.1089/nat.2019.0825. [Epub ahead of print]


Detection of the sickle hemoglobin allele using a surface plasmon resonance based biosensor.

Breveglieri G, D'Aversa E, Cosenza LC, Boutou E, Balassopoulou A, Voskaridou E, Gambari R, Borgatti M.

Sens Actuators B Chem. 2019 Oct 1;296:126604. doi: 10.1016/j.snb.2019.05.081.


Efficient Delivery of MicroRNA and AntimiRNA Molecules Using an Argininocalix[4]arene Macrocycle.

Gasparello J, Lomazzi M, Papi C, D'Aversa E, Sansone F, Casnati A, Donofrio G, Gambari R, Finotti A.

Mol Ther Nucleic Acids. 2019 Dec 6;18:748-763. doi: 10.1016/j.omtn.2019.09.029. Epub 2019 Oct 11.


Demonstrating specificity of bioactive peptide nucleic acids (PNAs) targeting microRNAs for practical laboratory classes of applied biochemistry and pharmacology.

Gasparello J, Papi C, Zurlo M, Corradini R, Gambari R, Finotti A.

PLoS One. 2019 Sep 11;14(9):e0221923. doi: 10.1371/journal.pone.0221923. eCollection 2019.


A new amido-phosphine of dichloroacetic acid as an active ligand for metals of pharmaceutical interest. Synthesis, characterization and tests of antiproliferative and pro-apoptotic activity.

Marvelli L, Ferretti V, Bertolasi V, Lampronti I, Gambari R, Trapella C, Turrin G, Bonotto F, Moriello A, Bergamini P.

J Inorg Biochem. 2019 Oct;199:110787. doi: 10.1016/j.jinorgbio.2019.110787. Epub 2019 Jul 22.


Increased frequency of activated CD8+ T cell effectors in patients with psoriatic arthritis.

Diani M, Casciano F, Marongiu L, Longhi M, Altomare A, Pigatto PD, Secchiero P, Gambari R, Banfi G, Manfredi AA, Altomare G, Granucci F, Reali E.

Sci Rep. 2019 Jul 26;9(1):10870. doi: 10.1038/s41598-019-47310-5.


Surface plasmon resonance based analysis of the binding of LYAR protein to the rs368698783 (G>A) polymorphic Aγ-globin gene sequences mutated in β-thalassemia.

Gemmo C, Breveglieri G, Marzaro G, Lampronti I, Cosenza LC, Gasparello J, Zuccato C, Fabbri E, Borgatti M, Chilin A, Finotti A, Gambari R.

Anal Bioanal Chem. 2019 Nov;411(29):7699-7707. doi: 10.1007/s00216-019-01987-9. Epub 2019 Jul 12.


Development and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of γ-globin and β-globin gene promoters.

Breveglieri G, Salvatori F, Finotti A, Cosenza LC, Zuccato C, Bianchi N, Breda L, Rivella S, Bresciani A, Bisbocci M, Borgatti M, Gambari R.

Anal Bioanal Chem. 2019 Nov;411(29):7669-7680. doi: 10.1007/s00216-019-01959-z. Epub 2019 Jul 4.


Targeting miR‑155‑5p and miR‑221‑3p by peptide nucleic acids induces caspase‑3 activation and apoptosis in temozolomide‑resistant T98G glioma cells.

Milani R, Brognara E, Fabbri E, Manicardi A, Corradini R, Finotti A, Gasparello J, Borgatti M, Cosenza LC, Lampronti I, Dechecchi MC, Cabrini G, Gambari R.

Int J Oncol. 2019 Jul;55(1):59-68. doi: 10.3892/ijo.2019.4810. Epub 2019 May 23.


Altered erythroid-related miRNA levels as a possible novel biomarker for detection of autologous blood transfusion misuse in sport.

Gasparello J, Lamberti N, Papi C, Lampronti I, Cosenza LC, Fabbri E, Bianchi N, Zambon C, Dalla Corte F, Govoni M, Reverberi R, Manfredini F, Gambari R, Finotti A.

Transfusion. 2019 Aug;59(8):2709-2721. doi: 10.1111/trf.15383. Epub 2019 May 30.


Exploring the effect of chirality on the therapeutic potential of N-alkyl-deoxyiminosugars: anti-inflammatory response to Pseudomonas aeruginosa infections for application in CF lung disease.

De Fenza M, D'Alonzo D, Esposito A, Munari S, Loberto N, Santangelo A, Lampronti I, Tamanini A, Rossi A, Ranucci S, De Fino I, Bragonzi A, Aureli M, Bassi R, Tironi M, Lippi G, Gambari R, Cabrini G, Palumbo G, Dechecchi MC, Guaragna A.

Eur J Med Chem. 2019 Aug 1;175:63-71. doi: 10.1016/j.ejmech.2019.04.061. Epub 2019 Apr 25.


Theranostics of Genetic Diseases.

Gambari R, Kleanthous M.

Mol Diagn Ther. 2019 Apr;23(2):153-154. doi: 10.1007/s40291-019-00395-0. No abstract available.


Efficient cell penetration and delivery of peptide nucleic acids by an argininocalix[4]arene.

Gasparello J, Manicardi A, Casnati A, Corradini R, Gambari R, Finotti A, Sansone F.

Sci Rep. 2019 Feb 28;9(1):3036. doi: 10.1038/s41598-019-39211-4.


Enhancing the Expression of CFTR Using Antisense Molecules against MicroRNA miR-145-5p.

Finotti A, Gasparello J, Fabbri E, Tamanini A, Corradini R, Dechecchi MC, Cabrini G, Gambari R.

Am J Respir Crit Care Med. 2019 Jun 1;199(11):1443-1444. doi: 10.1164/rccm.201901-0019LE. No abstract available.


MicroRNAs and Long Non-coding RNAs in Genetic Diseases.

Finotti A, Fabbri E, Lampronti I, Gasparello J, Borgatti M, Gambari R.

Mol Diagn Ther. 2019 Apr;23(2):155-171. doi: 10.1007/s40291-018-0380-6. Review.


Targeting DNA Binding for NF-κB as an Anticancer Approach in Hepatocellular Carcinoma.

Chung PY, Lam PL, Zhou YY, Gasparello J, Finotti A, Chilin A, Marzaro G, Gambari R, Bian ZX, Kwok WM, Wong WY, Wang X, Lam AK, Chan AS, Li X, Ma JY, Chui CH, Lam KH, Tang JC.

Cells. 2018 Oct 22;7(10). pii: E177. doi: 10.3390/cells7100177.


Synthesis of new allyl palladium complexes bearing purine-based NHC ligands with antiproliferative and proapoptotic activities on human ovarian cancer cell lines.

Scattolin T, Caligiuri I, Canovese L, Demitri N, Gambari R, Lampronti I, Rizzolio F, Santo C, Visentin F.

Dalton Trans. 2018 Oct 2;47(38):13616-13630. doi: 10.1039/c8dt01831f.


Non-invasive fetal sex diagnosis in plasma of early weeks pregnants using droplet digital PCR.

D'Aversa E, Breveglieri G, Pellegatti P, Guerra G, Gambari R, Borgatti M.

Mol Med. 2018 Apr 5;24(1):14. doi: 10.1186/s10020-018-0016-7.


Liquid biopsy and PCR-free ultrasensitive detection systems in oncology (Review).

Finotti A, Allegretti M, Gasparello J, Giacomini P, Spandidos DA, Spoto G, Gambari R.

Int J Oncol. 2018 Oct;53(4):1395-1434. doi: 10.3892/ijo.2018.4516. Epub 2018 Aug 6. Review.


Molecular Mechanism of Action of Trimethylangelicin Derivatives as CFTR Modulators.

Laselva O, Marzaro G, Vaccarin C, Lampronti I, Tamanini A, Lippi G, Gambari R, Cabrini G, Bear CE, Chilin A, Dechecchi MC.

Front Pharmacol. 2018 Jul 4;9:719. doi: 10.3389/fphar.2018.00719. eCollection 2018.

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