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Items: 1 to 20 of 46

1.

Structure-Immunogenicity Relationship of α- and β-Tetrasaccharide Glycoforms from Bacillus anthracis Exosporium and Fragments Thereof.

De Ricco R, Ventura CL, Carboni F, Saksena R, Kováč P, Adamo R.

Molecules. 2018 Aug 20;23(8). pii: E2079. doi: 10.3390/molecules23082079.

2.

Protein Carriers for Glycoconjugate Vaccines: History, Selection Criteria, Characterization and New Trends.

Micoli F, Adamo R, Costantino P.

Molecules. 2018 Jun 15;23(6). pii: E1451. doi: 10.3390/molecules23061451. Review.

3.

Fighting Antibiotic-Resistant Klebsiella pneumoniae with "Sweet" Immune Targets.

Adamo R, Margarit I.

MBio. 2018 May 15;9(3). pii: e00874-18. doi: 10.1128/mBio.00874-18.

4.

Potential targets for next generation antimicrobial glycoconjugate vaccines.

Micoli F, Costantino P, Adamo R.

FEMS Microbiol Rev. 2018 May 1;42(3):388-423. doi: 10.1093/femsre/fuy011.

5.

Combined Chemical Synthesis and Tailored Enzymatic Elongation Provide Fully Synthetic and Conjugation-Ready Neisseria meningitidis Serogroup X Vaccine Antigens.

Oldrini D, Fiebig T, Romano MR, Proietti D, Berger M, Tontini M, De Ricco R, Santini L, Morelli L, Lay L, Gerardy-Schahn R, Berti F, Adamo R.

ACS Chem Biol. 2018 Apr 20;13(4):984-994. doi: 10.1021/acschembio.7b01057. Epub 2018 Mar 1.

PMID:
29481045
6.

An efficient cell free enzyme-based total synthesis of a meningococcal vaccine candidate.

Fiebig T, Romano MR, Oldrini D, Adamo R, Tontini M, Brogioni B, Santini L, Berger M, Costantino P, Berti F, Gerardy-Schahn R.

NPJ Vaccines. 2016 Nov 15;1:16017. doi: 10.1038/npjvaccines.2016.17. eCollection 2016.

7.

Oxetane Grafts Installed Site-Selectively on Native Disulfides to Enhance Protein Stability and Activity In Vivo.

Martínez-Sáez N, Sun S, Oldrini D, Sormanni P, Boutureira O, Carboni F, Compañón I, Deery MJ, Vendruscolo M, Corzana F, Adamo R, Bernardes GJL.

Angew Chem Int Ed Engl. 2017 Nov 20;56(47):14963-14967. doi: 10.1002/anie.201708847. Epub 2017 Oct 20.

8.

Correction to "Advancing Homogeneous Antimicrobial Glycoconjugate Vaccines".

Adamo R.

Acc Chem Res. 2017 Jul 18;50(7):1794. doi: 10.1021/acs.accounts.7b00256. Epub 2017 Jun 27. No abstract available.

PMID:
28654238
9.

Optimizing adjuvants for intradermal delivery of MenC glycoconjugate vaccine.

Donadei A, Balocchi C, Romano MR, Panza L, Adamo R, Berti F, O'Hagan DT, Gallorini S, Baudner BC.

Vaccine. 2017 Jul 13;35(32):3930-3937. doi: 10.1016/j.vaccine.2017.06.018. Epub 2017 Jun 20.

PMID:
28645718
10.

Advancing Homogeneous Antimicrobial Glycoconjugate Vaccines.

Adamo R.

Acc Chem Res. 2017 May 16;50(5):1270-1279. doi: 10.1021/acs.accounts.7b00106. Epub 2017 May 2.

PMID:
28463499
11.

Structure of a protective epitope of group B Streptococcus type III capsular polysaccharide.

Carboni F, Adamo R, Fabbrini M, De Ricco R, Cattaneo V, Brogioni B, Veggi D, Pinto V, Passalacqua I, Oldrini D, Rappuoli R, Malito E, Margarit IYR, Berti F.

Proc Natl Acad Sci U S A. 2017 May 9;114(19):5017-5022. doi: 10.1073/pnas.1701885114. Epub 2017 Apr 24.

12.

Vaccinology Gets Help from Chemistry.

Adamo R.

Cell Chem Biol. 2016 Sep 22;23(9):1047-1048. doi: 10.1016/j.chembiol.2016.09.003.

13.

A Synthetic Disaccharide Analogue from Neisseria meningitidis A Capsular Polysaccharide Stimulates Immune Cell Responses and Induces Immunoglobulin G (IgG) Production in Mice When Protein-Conjugated.

Fallarini S, Buzzi B, Giovarruscio S, Polito L, Brogioni G, Tontini M, Berti F, Adamo R, Lay L, Lombardi G.

ACS Infect Dis. 2015 Oct 9;1(10):487-96. doi: 10.1021/acsinfecdis.5b00071. Epub 2015 Aug 17.

PMID:
27623315
14.

The adjuvant effect of TLR7 agonist conjugated to a meningococcal serogroup C glycoconjugate vaccine.

Donadei A, Balocchi C, Mancini F, Proietti D, Gallorini S, O'Hagan DT, D'Oro U, Berti F, Baudner BC, Adamo R.

Eur J Pharm Biopharm. 2016 Oct;107:110-9. doi: 10.1016/j.ejpb.2016.07.004. Epub 2016 Jul 5.

PMID:
27388628
15.

Towards the next generation of biomedicines by site-selective conjugation.

Hu QY, Berti F, Adamo R.

Chem Soc Rev. 2016 Mar 21;45(6):1691-719. doi: 10.1039/c4cs00388h. Review.

PMID:
26796469
16.

Correction to Exploring the Effect of Conjugation Site and Chemistry on the Immunogenicity of an anti-Group B Streptococcus Glycoconjugate Vaccine Based on GBS67 Pilus Protein and Type V Polysaccharide.

Nilo A, Passalacqua I, Fabbrini M, Allan M, Usera A, Carboni F, Brogioni B, Pezzicoli A, Cobb J, Romano MR, Margarit I, Hu QY, Berti F, Adamo R.

Bioconjug Chem. 2015 Oct 21;26(10):2167. doi: 10.1021/acs.bioconjchem.5b00480. Epub 2015 Sep 10. No abstract available.

PMID:
26355285
17.

Sugar-Protein Connectivity Impacts on the Immunogenicity of Site-Selective Salmonella O-Antigen Glycoconjugate Vaccines.

Stefanetti G, Hu QY, Usera A, Robinson Z, Allan M, Singh A, Imase H, Cobb J, Zhai H, Quinn D, Lei M, Saul A, Adamo R, MacLennan CA, Micoli F.

Angew Chem Int Ed Engl. 2015 Nov 2;54(45):13198-203. doi: 10.1002/anie.201506112. Epub 2015 Sep 9.

18.

Exploring the Effect of Conjugation Site and Chemistry on the Immunogenicity of an anti-Group B Streptococcus Glycoconjugate Vaccine Based on GBS67 Pilus Protein and Type V Polysaccharide.

Nilo A, Passalacqua I, Fabbrini M, Allan M, Usera A, Carboni F, Brogioni B, Pezzicoli A, Cobb J, Romano MR, Margarit I, Hu QY, Berti F, Adamo R.

Bioconjug Chem. 2015 Aug 19;26(8):1839-49. doi: 10.1021/acs.bioconjchem.5b00365. Epub 2015 Jul 31. Erratum in: Bioconjug Chem. 2015 Oct 21;26(10):2167.

PMID:
26230938
19.

Anti-Group B Streptococcus Glycan-Conjugate Vaccines Using Pilus Protein GBS80 As Carrier and Antigen: Comparing Lysine and Tyrosine-directed Conjugation.

Nilo A, Morelli L, Passalacqua I, Brogioni B, Allan M, Carboni F, Pezzicoli A, Zerbini F, Maione D, Fabbrini M, Romano MR, Hu QY, Margarit I, Berti F, Adamo R.

ACS Chem Biol. 2015 Jul 17;10(7):1737-46. doi: 10.1021/acschembio.5b00247. Epub 2015 May 6.

PMID:
25906283
20.

Rational Design of Adjuvant for Skin Delivery: Conjugation of Synthetic β-Glucan Dectin-1 Agonist to Protein Antigen.

Donadei A, Gallorini S, Berti F, O'Hagan DT, Adamo R, Baudner BC.

Mol Pharm. 2015 May 4;12(5):1662-72. doi: 10.1021/acs.molpharmaceut.5b00072. Epub 2015 Apr 20.

PMID:
25867449

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