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Items: 16


Flavin Oxidase-Induced ROS Generation Modulates PKC Biphasic Effect of Resveratrol on Endothelial Cell Survival.

Posadino AM, Giordo R, Cossu A, Nasrallah GK, Shaito A, Abou-Saleh H, Eid AH, Pintus G.

Biomolecules. 2019 May 30;9(6). pii: E209. doi: 10.3390/biom9060209.


Antioxidant Activity Mediates Pirfenidone Antifibrotic Effects in Human Pulmonary Vascular Smooth Muscle Cells Exposed to Sera of Idiopathic Pulmonary Fibrosis Patients.

Fois AG, Posadino AM, Giordo R, Cossu A, Agouni A, Rizk NM, Pirina P, Carru C, Zinellu A, Pintus G.

Oxid Med Cell Longev. 2018 Oct 21;2018:2639081. doi: 10.1155/2018/2639081. eCollection 2018.


Protective Effect of Cyclically Pressurized Solid⁻Liquid Extraction Polyphenols from Cagnulari Grape Pomace on Oxidative Endothelial Cell Death.

Posadino AM, Biosa G, Zayed H, Abou-Saleh H, Cossu A, Nasrallah GK, Giordo R, Pagnozzi D, Porcu MC, Pretti L, Pintus G.

Molecules. 2018 Aug 21;23(9). pii: E2105. doi: 10.3390/molecules23092105.


Reduced vasorin enhances angiotensin II signaling within the aging arterial wall.

Pintus G, Giordo R, Wang Y, Zhu W, Kim SH, Zhang L, Ni L, Zhang J, Telljohann R, McGraw KR, Monticone RE, Ferris C, Liu L, Wang M, Lakatta EG.

Oncotarget. 2018 Jun 5;9(43):27117-27132. doi: 10.18632/oncotarget.25499. eCollection 2018 Jun 5.


Oxidative stress-induced Akt downregulation mediates green tea toxicity towards prostate cancer cells.

Posadino AM, Phu HT, Cossu A, Giordo R, Fois M, Thuan DTB, Piga A, Sotgia S, Zinellu A, Carru C, Pintus G.

Toxicol In Vitro. 2017 Aug;42:255-262. doi: 10.1016/j.tiv.2017.05.005. Epub 2017 May 7.


Activation of the Pro-Oxidant PKCβII-p66Shc Signaling Pathway Contributes to Pericyte Dysfunction in Skeletal Muscles of Patients With Diabetes With Critical Limb Ischemia.

Vono R, Fuoco C, Testa S, Pirrò S, Maselli D, Ferland McCollough D, Sangalli E, Pintus G, Giordo R, Finzi G, Sessa F, Cardani R, Gotti A, Losa S, Cesareni G, Rizzi R, Bearzi C, Cannata S, Spinetti G, Gargioli C, Madeddu P.

Diabetes. 2016 Dec;65(12):3691-3704. Epub 2016 Sep 6.


N- and S-homocysteinylation reduce the binding of human serum albumin to catechins.

Zinellu A, Sotgia S, Scanu B, Arru D, Cossu A, Posadino AM, Giordo R, Mangoni AA, Pintus G, Carru C.

Eur J Nutr. 2017 Mar;56(2):785-791. doi: 10.1007/s00394-015-1125-5. Epub 2015 Dec 10.


Human Serum Albumin Increases the Stability of Green Tea Catechins in Aqueous Physiological Conditions.

Zinellu A, Sotgia S, Scanu B, Forteschi M, Giordo R, Cossu A, Posadino AM, Carru C, Pintus G.

PLoS One. 2015 Jul 31;10(7):e0134690. doi: 10.1371/journal.pone.0134690. eCollection 2015.


Resveratrol alters human endothelial cells redox state and causes mitochondrial-dependent cell death.

Posadino AM, Cossu A, Giordo R, Zinellu A, Sotgia S, Vardeu A, Hoa PT, Nguyen le HV, Carru C, Pintus G.

Food Chem Toxicol. 2015 Apr;78:10-6. doi: 10.1016/j.fct.2015.01.017. Epub 2015 Feb 2.


Evaluation of non-covalent interactions between serum albumin and green tea catechins by affinity capillary electrophoresis.

Zinellu A, Sotgia S, Scanu B, Pisanu E, Giordo R, Cossu A, Posadino AM, Carru C, Pintus G.

J Chromatogr A. 2014 Nov 7;1367:167-71. doi: 10.1016/j.chroma.2014.09.053. Epub 2014 Sep 30.


Oxidative stress-dependent activation of collagen synthesis is induced in human pulmonary smooth muscle cells by sera from patients with scleroderma-associated pulmonary hypertension.

Boin F, Erre GL, Posadino AM, Cossu A, Giordo R, Spinetti G, Passiu G, Emanueli C, Pintus G.

Orphanet J Rare Dis. 2014 Aug 1;9:123. doi: 10.1186/s13023-014-0123-7.


Different redox response elicited by naturally occurring antioxidants in human endothelial cells.

Giordo R, Cossu A, Pasciu V, Hoa PT, Posadino AM, Pintus G.

Open Biochem J. 2013 Apr 19;7:44-53. doi: 10.2174/1874091X01307010044. Print 2013.


Coumaric acid induces mitochondrial damage and oxidative-mediated cell death of human endothelial cells.

Posadino AM, Cossu A, Giordo R, Zinellu A, Sotgia S, Vardeu A, Hoa PT, Deiana L, Carru C, Pintus G.

Cardiovasc Toxicol. 2013 Sep;13(3):301-6. doi: 10.1007/s12012-013-9205-3.


Apricot melanoidins prevent oxidative endothelial cell death by counteracting mitochondrial oxidation and membrane depolarization.

Cossu A, Posadino AM, Giordo R, Emanueli C, Sanguinetti AM, Piscopo A, Poiana M, Capobianco G, Piga A, Pintus G.

PLoS One. 2012;7(11):e48817. doi: 10.1371/journal.pone.0048817. Epub 2012 Nov 8.


The E2FD/DEL2 factor is a component of a regulatory network controlling cell proliferation and development in Arabidopsis.

Sozzani R, Maggio C, Giordo R, Umana E, Ascencio-Ibañez JT, Hanley-Bowdoin L, Bergounioux C, Cella R, Albani D.

Plant Mol Biol. 2010 Mar;72(4-5):381-95. doi: 10.1007/s11103-009-9577-8. Epub 2009 Nov 25.


MAP kinases MPK9 and MPK12 are preferentially expressed in guard cells and positively regulate ROS-mediated ABA signaling.

Jammes F, Song C, Shin D, Munemasa S, Takeda K, Gu D, Cho D, Lee S, Giordo R, Sritubtim S, Leonhardt N, Ellis BE, Murata Y, Kwak JM.

Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20520-5. doi: 10.1073/pnas.0907205106. Epub 2009 Nov 12.

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