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Items: 1 to 20 of 124


Molecular Imaging of Galectin-1 Expression as a Biomarker of Papillary Thyroid Cancer by Using Peptide-Functionalized Imaging Probes.

Fanfone D, Stanicki D, Nonclercq D, Port M, Vander Elst L, Laurent S, Muller RN, Saussez S, Burtea C.

Biology (Basel). 2020 Mar 14;9(3). pii: E53. doi: 10.3390/biology9030053.


Modulation of adiponectin receptors AdipoR1 and AdipoR2 by phage display-derived peptides in in vitro and in vivo models.

Crombez D, Delcambre S, Nonclercq D, Vander Elst L, Laurent S, Cnop M, Muller RN, Burtea C.

J Drug Target. 2020 Jan 10:1-21. doi: 10.1080/1061186X.2019.1710840. [Epub ahead of print]


Synthesis and Relaxometric Characterization of New Poly[N,N-bis(3-aminopropyl)glycine] (PAPGly) Dendrons Gd-Based Contrast Agents and Their in Vivo Study by Using the Dynamic Contrast-Enhanced MRI Technique at Low Field (1 T).

Granato L, Longo D, Boutry S, Vander Elst L, Henoumont C, Aime S, Muller RN, Laurent S.

Chem Biodivers. 2019 Nov;16(11):e1900322. doi: 10.1002/cbdv.201900322. Epub 2019 Oct 29.


Comparison of MRI Properties between Multimeric DOTAGA and DO3A Gadolinium-Dendron Conjugates.

Ndiaye M, Malytskyi V, Vangijzegem T, Sauvage F, Wels M, Cadiou C, Moreau J, Henoumont C, Boutry S, Muller RN, Harakat D, Smedt S, Laurent S, Chuburu F.

Inorg Chem. 2019 Oct 7;58(19):12798-12808. doi: 10.1021/acs.inorgchem.9b01747. Epub 2019 Sep 9.


Embedding of superparamagnetic iron oxide nanoparticles into membranes of well-defined poly(ethylene oxide)-block-poly(ε-caprolactone) nanoscale magnetovesicles as ultrasensitive MRI probes of membrane bio-degradation.

Hannecart A, Stanicki D, Vander Elst L, Muller RN, Brûlet A, Sandre O, Schatz C, Lecommandoux S, Laurent S.

J Mater Chem B. 2019 Jul 31;7(30):4692-4705. doi: 10.1039/c9tb00909d.


Fluorinated MRI contrast agents and their versatile applications in the biomedical field.

Hequet E, Henoumont C, Muller RN, Laurent S.

Future Med Chem. 2019 May;11(10):1157-1175. doi: 10.4155/fmc-2018-0463. Review.


Influence of experimental parameters on iron oxide nanoparticle properties synthesized by thermal decomposition: size and nuclear magnetic resonance studies.

Belaïd S, Stanicki D, Vander Elst L, Muller RN, Laurent S.

Nanotechnology. 2018 Apr 20;29(16):165603. doi: 10.1088/1361-6528/aaae59.


Optimizing Water Exchange Rates and Rotational Mobility for High-Relaxivity of a Novel Gd-DO3A Derivative Complex Conjugated to Inulin as Macromolecular Contrast Agents for MRI.

Granato L, Vander Elst L, Henoumont C, Muller RN, Laurent S.

Chem Biodivers. 2018 Feb;15(2). doi: 10.1002/cbdv.201700487. Epub 2018 Feb 20.


Validation by Magnetic Resonance Imaging of the Diagnostic Potential of a Heptapeptide-Functionalized Imaging Probe Targeted to Amyloid-β and Able to Cross the Blood-Brain Barrier.

André S, Ansciaux E, Saidi E, Larbanoix L, Stanicki D, Nonclercq D, Vander Elst L, Laurent S, Muller RN, Burtea C.

J Alzheimers Dis. 2017;60(4):1547-1565. doi: 10.3233/JAD-170563.


Toward a new and noninvasive diagnostic method of papillary thyroid cancer by using peptide vectorized contrast agents targeted to galectin-1.

Fanfone D, Despretz N, Stanicki D, Rubio-Magnieto J, Fossépré M, Surin M, Rorive S, Salmon I, Vander Elst L, Laurent S, Muller RN, Saussez S, Burtea C.

Med Oncol. 2017 Oct 6;34(11):184. doi: 10.1007/s12032-017-1042-y.


Synthesis and Characterization of PEGylated and Fluorinated Chitosans: Application to the Synthesis of Targeted Nanoparticles for Drug Delivery.

Belabassi Y, Moreau J, Gheran V, Henoumont C, Robert A, Callewaert M, Rigaux G, Cadiou C, Vander Elst L, Laurent S, Muller RN, Dinischiotu A, Voicu SN, Chuburu F.

Biomacromolecules. 2017 Sep 11;18(9):2756-2766. doi: 10.1021/acs.biomac.7b00668. Epub 2017 Aug 24.


Synthesis and characterization of monophosphinic acid DOTA derivative: A smart tool with functionalities for multimodal imaging.

Chilla SNM, Zemek O, Kotek J, Boutry S, Larbanoix L, Sclavons C, Elst LV, Lukes I, Muller RN, Laurent S.

Bioorg Med Chem. 2017 Aug 15;25(16):4297-4303. doi: 10.1016/j.bmc.2017.06.008. Epub 2017 Jun 15.


Biocompatible and fluorescent superparamagnetic iron oxide nanoparticles with superior magnetic properties coated with charged polysaccharide derivatives.

Lachowicz D, Szpak A, Malek-Zietek KE, Kepczynski M, Muller RN, Laurent S, Nowakowska M, Zapotoczny S.

Colloids Surf B Biointerfaces. 2017 Feb 1;150:402-407. doi: 10.1016/j.colsurfb.2016.11.003. Epub 2016 Nov 2.


Chemical and in vitro characterizations of a promising bimodal AGuIX probe able to target apoptotic cells for applications in MRI and optical imaging.

Dentamaro M, Lux F, Vander Elst L, Dauguet N, Montante S, Moussaron A, Burtea C, Muller RN, Tillement O, Laurent S.

Contrast Media Mol Imaging. 2016 Sep;11(5):381-395. doi: 10.1002/cmmi.1702. Epub 2016 Jul 19.


Screening for peptides targeted to IL-7Rα for molecular imaging of rheumatoid arthritis synovium.

Burtea C, Laurent S, Sanli T, Fanfone D, Devalckeneer A, Sauvage S, Beckers MC, Rorive S, Salmon I, Vander Elst L, Lauwerys BR, Muller RN.

Arthritis Res Ther. 2016 Oct 12;18(1):230.


A regulatable AAV vector mediating GDNF biological effects at clinically-approved sub-antimicrobial doxycycline doses.

Chtarto A, Humbert-Claude M, Bockstael O, Das AT, Boutry S, Breger LS, Klaver B, Melas C, Barroso-Chinea P, Gonzalez-Hernandez T, Muller RN, DeWitte O, Levivier M, Lundberg C, Berkhout B, Tenenbaum L.

Mol Ther Methods Clin Dev. 2016 Mar 30;5:16027. doi: 10.1038/mtm.2016.27. eCollection 2016.


Early detection of colonic dysplasia by magnetic resonance molecular imaging with a contrast agent raised against the colon cancer marker MUC5AC.

Rossez Y, Burtea C, Laurent S, Gosset P, Léonard R, Gonzalez W, Ballet S, Raynal I, Rousseaux O, Dugué T, Vander Elst L, Michalski JC, Muller RN, Robbe-Masselot C.

Contrast Media Mol Imaging. 2016 May;11(3):211-21. doi: 10.1002/cmmi.1682. Epub 2016 Jan 14.


(1) H-NMR relaxometric studies of interaction between apoptosis specific MRI paramagnetic contrast agents and micellar models of apoptotic cells.

Van Koninckxloo A, Henoumont C, Laurent S, Muller RN, Vander Elst L.

Magn Reson Chem. 2016 Jul;54(7):568-74. doi: 10.1002/mrc.4397. Epub 2015 Dec 9.


Assembly of near infra-red emitting upconverting nanoparticles and multiple Gd(III)-chelates as a potential bimodal contrast agent for MRI and optical imaging.

Carron S, Li QY, Vander Elst L, Muller RN, Parac-Vogt TN, Capobianco JA.

Dalton Trans. 2015 Jul 7;44(25):11331-9. doi: 10.1039/c5dt00919g.


Development of a peptide-functionalized imaging nanoprobe for the targeting of (FXYD2)γa as a highly specific biomarker of pancreatic beta cells.

Burtea C, Laurent S, Crombez D, Delcambre S, Sermeus C, Millard I, Rorive S, Flamez D, Beckers MC, Salmon I, Vander Elst L, Eizirik DL, Muller RN.

Contrast Media Mol Imaging. 2015 Sep-Oct;10(5):398-412. doi: 10.1002/cmmi.1641. Epub 2015 Apr 30.

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