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Items: 1 to 20 of 21


Wnt-11 as a Potential Prognostic Biomarker and Therapeutic Target in Colorectal Cancer.

Gorroño-Etxebarria I, Aguirre U, Sanchez S, González N, Escobar A, Zabalza I, Quintana JM, Vivanco MD, Waxman J, Kypta RM.

Cancers (Basel). 2019 Jun 28;11(7). pii: E908. doi: 10.3390/cancers11070908.


A Sox2-Sox9 signalling axis maintains human breast luminal progenitor and breast cancer stem cells.

Domenici G, Aurrekoetxea-Rodríguez I, Simões BM, Rábano M, Lee SY, Millán JS, Comaills V, Oliemuller E, López-Ruiz JA, Zabalza I, Howard BA, Kypta RM, Vivanco MD.

Oncogene. 2019 Apr;38(17):3151-3169. doi: 10.1038/s41388-018-0656-7. Epub 2019 Jan 8.


Proteomic Studies Reveal Disrupted in Schizophrenia 1 as a Player in Both Neurodevelopment and Synaptic Function.

Ramos A, Rodríguez-Seoane C, Rosa I, Gorroño-Etxebarria I, Alonso J, Veiga S, Korth C, Kypta RM, García Á, Requena JR.

Int J Mol Sci. 2018 Dec 29;20(1). pii: E119. doi: 10.3390/ijms20010119.


In Silico Approach for Immunohistochemical Evaluation of a Cytoplasmic Marker in Breast Cancer.

Mazo C, Orue-Etxebarria E, Zabalza I, Vivanco MDM, Kypta RM, Beristain A.

Cancers (Basel). 2018 Dec 15;10(12). pii: E517. doi: 10.3390/cancers10120517.


Protective effect of stromal Dickkopf-3 in prostate cancer: opposing roles for TGFBI and ECM-1.

Al Shareef Z, Kardooni H, Murillo-Garzón V, Domenici G, Stylianakis E, Steel JH, Rabano M, Gorroño-Etxebarria I, Zabalza I, Vivanco MD, Waxman J, Kypta RM.

Oncogene. 2018 Sep;37(39):5305-5324. doi: 10.1038/s41388-018-0294-0. Epub 2018 Jun 1.


CRISPR-Mediated Reactivation of DKK3 Expression Attenuates TGF-β Signaling in Prostate Cancer.

Kardooni H, Gonzalez-Gualda E, Stylianakis E, Saffaran S, Waxman J, Kypta RM.

Cancers (Basel). 2018 May 28;10(6). pii: E165. doi: 10.3390/cancers10060165.


Frizzled-8 integrates Wnt-11 and transforming growth factor-β signaling in prostate cancer.

Murillo-Garzón V, Gorroño-Etxebarria I, Åkerfelt M, Puustinen MC, Sistonen L, Nees M, Carton J, Waxman J, Kypta RM.

Nat Commun. 2018 May 1;9(1):1747. doi: 10.1038/s41467-018-04042-w.


Canonical and noncanonical Wnt signaling in neural stem/progenitor cells.

Bengoa-Vergniory N, Kypta RM.

Cell Mol Life Sci. 2015 Nov;72(21):4157-72. doi: 10.1007/s00018-015-2028-6. Epub 2015 Aug 26. Review.


A screen for transcription factor targets of glycogen synthase kinase-3 highlights an inverse correlation of NFκB and androgen receptor signaling in prostate cancer.

Campa VM, Baltziskueta E, Bengoa-Vergniory N, Gorroño-Etxebarria I, Wesołowski R, Waxman J, Kypta RM.

Oncotarget. 2014 Sep 30;5(18):8173-87.


A switch from canonical to noncanonical Wnt signaling mediates early differentiation of human neural stem cells.

Bengoa-Vergniory N, Gorroño-Etxebarria I, González-Salazar I, Kypta RM.

Stem Cells. 2014 Dec;32(12):3196-208. doi: 10.1002/stem.1807.


Wnt/β-catenin signalling in prostate cancer.

Kypta RM, Waxman J.

Nat Rev Urol. 2012 Aug;9(8):418-28. doi: 10.1038/nrurol.2012.116. Epub 2012 Jun 19. Review.


Distinct expression and activity of GSK-3α and GSK-3β in prostate cancer.

Darrington RS, Campa VM, Walker MM, Bengoa-Vergniory N, Gorrono-Etxebarria I, Uysal-Onganer P, Kawano Y, Waxman J, Kypta RM.

Int J Cancer. 2012 Sep 15;131(6):E872-83. doi: 10.1002/ijc.27620. Epub 2012 May 22.


Distinct roles for Wnt-4 and Wnt-11 during retinoic acid-induced neuronal differentiation.

Elizalde C, Campa VM, Caro M, Schlangen K, Aransay AM, Vivanco Md, Kypta RM.

Stem Cells. 2011 Jan;29(1):141-53. doi: 10.1002/stem.562.


Wnt-11 promotes neuroendocrine-like differentiation, survival and migration of prostate cancer cells.

Uysal-Onganer P, Kawano Y, Caro M, Walker MM, Diez S, Darrington RS, Waxman J, Kypta RM.

Mol Cancer. 2010 Mar 10;9:55. doi: 10.1186/1476-4598-9-55.


The neuron-specific isoform of glycogen synthase kinase-3beta is required for axon growth.

Castaño Z, Gordon-Weeks PR, Kypta RM.

J Neurochem. 2010 Apr;113(1):117-30. doi: 10.1111/j.1471-4159.2010.06581.x. Epub 2010 Jan 12.


Analysis of Wnt gene expression in prostate cancer: mutual inhibition by WNT11 and the androgen receptor.

Zhu H, Mazor M, Kawano Y, Walker MM, Leung HY, Armstrong K, Waxman J, Kypta RM.

Cancer Res. 2004 Nov 1;64(21):7918-26. Erratum in: Cancer Res. 2005 Sep 1;65(17):8057.


Inhibition of glycogen synthase kinase-3 represses androgen receptor activity and prostate cancer cell growth.

Mazor M, Kawano Y, Zhu H, Waxman J, Kypta RM.

Oncogene. 2004 Oct 14;23(47):7882-92.


Glucocorticoids inhibit apoptosis during fibrosarcoma development by transcriptionally activating Bcl-xL.

Gascoyne DM, Kypta RM, Vivanco Md.

J Biol Chem. 2003 May 16;278(20):18022-9. Epub 2003 Mar 12.

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