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Items: 1 to 20 of 130

1.

Synergistic Biophysical Techniques Reveal Structural Mechanisms of Engineered Cationic Antimicrobial Peptides in Lipid Model Membranes.

Heinrich F, Salyapongse A, Kumagai A, Dupuy FG, Shukla K, Penk A, Huster D, Ernst RK, Pavlova A, Gumbart JC, Deslouches B, Di YP, Tristram-Nagle S.

Chemistry. 2020 Mar 13. doi: 10.1002/chem.202000212. [Epub ahead of print]

PMID:
32166806
2.

Toll-like Receptor 4-Independent Effects of Lipopolysaccharide Identified Using Longitudinal Serum Proteomics.

Harberts E, Liang T, Yoon SH, Opene BN, McFarland MA, Goodlett DR, Ernst RK.

J Proteome Res. 2020 Mar 6;19(3):1258-1266. doi: 10.1021/acs.jproteome.9b00765. Epub 2020 Feb 24.

3.

Maintenance of Deep Lung Architecture and Automated Airway Segmentation for 3D Mass Spectrometry Imaging.

Scott AJ, Chandler CE, Ellis SR, Heeren RMA, Ernst RK.

Sci Rep. 2019 Dec 27;9(1):20160. doi: 10.1038/s41598-019-56364-4.

4.

The UDP-GalNAcA biosynthesis genes gna-gne2 are required to maintain cell envelope integrity and in vivo fitness in multi-drug resistant Acinetobacter baumannii.

Crépin S, Ottosen EN, Chandler CE, Sintsova A, Ernst RK, Mobley HLT.

Mol Microbiol. 2020 Jan;113(1):153-172. doi: 10.1111/mmi.14407. Epub 2019 Nov 19.

PMID:
31680352
5.

Lipopolysaccharides from Different Burkholderia Species with Different Lipid A Structures Induce Toll-Like Receptor 4 Activation and React with Melioidosis Patient Sera.

Sengyee S, Yoon SH, West TE, Ernst RK, Chantratita N.

Infect Immun. 2019 Nov 18;87(12). pii: e00692-19. doi: 10.1128/IAI.00692-19. Print 2019 Dec.

6.

Repurposing Eukaryotic Kinase Inhibitors as Colistin Adjuvants in Gram-Negative Bacteria.

Barker WT, Nemeth AM, Brackett SM, Basak AK, Chandler CE, Jania LA, Zuercher WJ, Melander RJ, Koller BH, Ernst RK, Melander C.

ACS Infect Dis. 2019 Oct 11;5(10):1764-1771. doi: 10.1021/acsinfecdis.9b00212. Epub 2019 Sep 4.

PMID:
31434474
7.

Efflux Pumps of Burkholderia thailandensis Control the Permeability Barrier of the Outer Membrane.

Krishnamoorthy G, Weeks JW, Zhang Z, Chandler CE, Xue H, Schweizer HP, Ernst RK, Zgurskaya HI.

Antimicrob Agents Chemother. 2019 Sep 23;63(10). pii: e00956-19. doi: 10.1128/AAC.00956-19. Print 2019 Oct.

8.

Model-Based Spectral Library Approach for Bacterial Identification via Membrane Glycolipids.

Ryu SY, Wendt GA, Chandler CE, Ernst RK, Goodlett DR.

Anal Chem. 2019 Sep 3;91(17):11482-11487. doi: 10.1021/acs.analchem.9b03340. Epub 2019 Aug 15.

PMID:
31369253
9.

Small Molecule Potentiation of Gram-Positive Selective Antibiotics against Acinetobacter baumannii.

Martin SE, Melander RJ, Brackett CM, Scott AJ, Chandler CE, Nguyen CM, Minrovic BM, Harrill SE, Ernst RK, Manoil C, Melander C.

ACS Infect Dis. 2019 Jul 12;5(7):1223-1230. doi: 10.1021/acsinfecdis.9b00067. Epub 2019 Apr 26.

PMID:
31002491
10.

Bacterial medium-chain 3-hydroxy fatty acid metabolites trigger immunity in Arabidopsis plants.

Kutschera A, Dawid C, Gisch N, Schmid C, Raasch L, Gerster T, Schäffer M, Smakowska-Luzan E, Belkhadir Y, Vlot AC, Chandler CE, Schellenberger R, Schwudke D, Ernst RK, Dorey S, Hückelhoven R, Hofmann T, Ranf S.

Science. 2019 Apr 12;364(6436):178-181. doi: 10.1126/science.aau1279.

PMID:
30975887
11.

Tryptamine derivatives disarm colistin resistance in polymyxin-resistant gram-negative bacteria.

Barker WT, Chandler CE, Melander RJ, Ernst RK, Melander C.

Bioorg Med Chem. 2019 May 1;27(9):1776-1788. doi: 10.1016/j.bmc.2019.03.019. Epub 2019 Mar 8.

PMID:
30898435
12.

Analysis of Pseudomonas aeruginosa biofilm membrane vesicles supports multiple mechanisms of biogenesis.

Cooke AC, Nello AV, Ernst RK, Schertzer JW.

PLoS One. 2019 Feb 14;14(2):e0212275. doi: 10.1371/journal.pone.0212275. eCollection 2019.

13.

Temporal proteomic profiling reveals changes that support Burkholderia biofilms.

Khan MM, Chattagul S, Tran BQ, Freiberg JA, Nita-Lazar A, Shirtliff ME, Sermswan RW, Ernst RK, Goodlett DR.

Pathog Dis. 2019 Mar 1;77(2). pii: ftz005. doi: 10.1093/femspd/ftz005.

14.

Elastic behavior of model membranes with antimicrobial peptides depends on lipid specificity and d-enantiomers.

Kumagai A, Dupuy FG, Arsov Z, Elhady Y, Moody D, Ernst RK, Deslouches B, Montelaro RC, Peter Di Y, Tristram-Nagle S.

Soft Matter. 2019 Feb 20;15(8):1860-1868. doi: 10.1039/c8sm02180e.

PMID:
30702120
15.

Rapid Microbial Identification and Antibiotic Resistance Detection by Mass Spectrometric Analysis of Membrane Lipids.

Liang T, Leung LM, Opene B, Fondrie WE, Lee YI, Chandler CE, Yoon SH, Doi Y, Ernst RK, Goodlett DR.

Anal Chem. 2019 Jan 15;91(2):1286-1294. doi: 10.1021/acs.analchem.8b02611. Epub 2019 Jan 4.

PMID:
30571097
16.

A Prospective Study of Acinetobacter baumannii Complex Isolates and Colistin Susceptibility Monitoring by Mass Spectrometry of Microbial Membrane Glycolipids.

Leung LM, McElheny CL, Gardner FM, Chandler CE, Bowler SL, Mettus RT, Spychala CN, Fowler EL, Opene BNA, Myers RA, Goodlett DR, Doi Y, Ernst RK.

J Clin Microbiol. 2019 Feb 27;57(3). pii: e01100-18. doi: 10.1128/JCM.01100-18. Print 2019 Mar.

17.

Genomic and Phenotypic Diversity among Ten Laboratory Isolates of Pseudomonas aeruginosa PAO1.

Chandler CE, Horspool AM, Hill PJ, Wozniak DJ, Schertzer JW, Rasko DA, Ernst RK.

J Bacteriol. 2019 Feb 11;201(5). pii: e00595-18. doi: 10.1128/JB.00595-18. Print 2019 Mar 1.

18.

Pathogen Identification Direct From Polymicrobial Specimens Using Membrane Glycolipids.

Fondrie WE, Liang T, Oyler BL, Leung LM, Ernst RK, Strickland DK, Goodlett DR.

Sci Rep. 2018 Oct 26;8(1):15857. doi: 10.1038/s41598-018-33681-8.

19.

Phylogenomics of colistin-susceptible and resistant XDR Acinetobacter baumannii.

Mustapha MM, Li B, Pacey MP, Mettus RT, McElheny CL, Marshall CW, Ernst RK, Cooper VS, Doi Y.

J Antimicrob Chemother. 2018 Nov 1;73(11):2952-2959. doi: 10.1093/jac/dky290.

20.

Rickettsia Lipid A Biosynthesis Utilizes the Late Acyltransferase LpxJ for Secondary Fatty Acid Addition.

Guillotte ML, Gillespie JJ, Chandler CE, Rahman MS, Ernst RK, Azad AF.

J Bacteriol. 2018 Sep 10;200(19). pii: e00334-18. doi: 10.1128/JB.00334-18. Print 2018 Oct 1.

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