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Items: 13

1.

Phospho-dependent phase separation of FMRP and CAPRIN1 recapitulates regulation of translation and deadenylation.

Kim TH, Tsang B, Vernon RM, Sonenberg N, Kay LE, Forman-Kay JD.

Science. 2019 Aug 23;365(6455):825-829. doi: 10.1126/science.aax4240.

PMID:
31439799
2.

Translating Material Science into Biological Function.

Vernon RM, Forman-Kay JD.

Mol Cell. 2019 Jul 11;75(1):1-2. doi: 10.1016/j.molcel.2019.06.021.

PMID:
31299205
3.

First-generation predictors of biological protein phase separation.

Vernon RM, Forman-Kay JD.

Curr Opin Struct Biol. 2019 Jun 25;58:88-96. doi: 10.1016/j.sbi.2019.05.016. [Epub ahead of print] Review.

PMID:
31252218
4.

Temperature, Hydrostatic Pressure, and Osmolyte Effects on Liquid-Liquid Phase Separation in Protein Condensates: Physical Chemistry and Biological Implications.

Cinar H, Fetahaj Z, Cinar S, Vernon RM, Chan HS, Winter RHA.

Chemistry. 2019 Jun 25. doi: 10.1002/chem.201902210. [Epub ahead of print] Review.

PMID:
31237369
5.

Phosphoregulated FMRP phase separation models activity-dependent translation through bidirectional control of mRNA granule formation.

Tsang B, Arsenault J, Vernon RM, Lin H, Sonenberg N, Wang LY, Bah A, Forman-Kay JD.

Proc Natl Acad Sci U S A. 2019 Feb 14. pii: 201814385. doi: 10.1073/pnas.1814385116. [Epub ahead of print]

PMID:
30765518
6.

Physiologically Important Electrolytes as Regulators of TDP-43 Aggregation and Droplet-Phase Behavior.

Sun Y, Medina Cruz A, Hadley KC, Galant NJ, Law R, Vernon RM, Morris VK, Robertson J, Chakrabartty A.

Biochemistry. 2019 Feb 12;58(6):590-607. doi: 10.1021/acs.biochem.8b00842. Epub 2018 Dec 13.

PMID:
30489059
7.

RGG/RG Motif Regions in RNA Binding and Phase Separation.

Chong PA, Vernon RM, Forman-Kay JD.

J Mol Biol. 2018 Nov 2;430(23):4650-4665. doi: 10.1016/j.jmb.2018.06.014. Epub 2018 Jun 15. Review.

PMID:
29913160
8.

Stabilization of a nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator yields insight into disease-causing mutations.

Vernon RM, Chong PA, Lin H, Yang Z, Zhou Q, Aleksandrov AA, Dawson JE, Riordan JR, Brouillette CG, Thibodeau PH, Forman-Kay JD.

J Biol Chem. 2017 Aug 25;292(34):14147-14164. doi: 10.1074/jbc.M116.772335. Epub 2017 Jun 27.

9.

Deletion of Phenylalanine 508 in the First Nucleotide-binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator Increases Conformational Exchange and Inhibits Dimerization.

Chong PA, Farber PJ, Vernon RM, Hudson RP, Mittermaier AK, Forman-Kay JD.

J Biol Chem. 2015 Sep 18;290(38):22862-78. doi: 10.1074/jbc.M115.641134. Epub 2015 Jul 6.

10.

Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch.

Bah A, Vernon RM, Siddiqui Z, Krzeminski M, Muhandiram R, Zhao C, Sonenberg N, Kay LE, Forman-Kay JD.

Nature. 2015 Mar 5;519(7541):106-9. doi: 10.1038/nature13999. Epub 2014 Dec 22.

PMID:
25533957
11.

Generalized fragment picking in Rosetta: design, protocols and applications.

Gront D, Kulp DW, Vernon RM, Strauss CE, Baker D.

PLoS One. 2011;6(8):e23294. doi: 10.1371/journal.pone.0023294. Epub 2011 Aug 24.

12.

Solution structure of a minor and transiently formed state of a T4 lysozyme mutant.

Bouvignies G, Vallurupalli P, Hansen DF, Correia BE, Lange O, Bah A, Vernon RM, Dahlquist FW, Baker D, Kay LE.

Nature. 2011 Aug 21;477(7362):111-4. doi: 10.1038/nature10349.

13.

Nonnative interactions in the FF domain folding pathway from an atomic resolution structure of a sparsely populated intermediate: an NMR relaxation dispersion study.

Korzhnev DM, Vernon RM, Religa TL, Hansen AL, Baker D, Fersht AR, Kay LE.

J Am Chem Soc. 2011 Jul 20;133(28):10974-82. doi: 10.1021/ja203686t. Epub 2011 Jun 28.

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