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Elucidating Transmission Patterns of Endemic Mycobacterium avium subsp. paratuberculosis Using Molecular Epidemiology.

Mitchell RM, Beaver A, Knupfer E, Pradhan AK, Fyock T, Whitlock RH, Schukken YH.

Vet Sci. 2019 Mar 20;6(1). pii: E32. doi: 10.3390/vetsci6010032.


Impact of the shedding level on transmission of persistent infections in Mycobacterium avium subspecies paratuberculosis (MAP).

Slater N, Mitchell RM, Whitlock RH, Fyock T, Pradhan AK, Knupfer E, Schukken YH, Louzoun Y.

Vet Res. 2016 Feb 29;47:38. doi: 10.1186/s13567-016-0323-3.


Differences in intermittent and continuous fecal shedding patterns between natural and experimental Mycobacterium avium subspecies paratuberculosis infections in cattle.

Mitchell RM, Schukken Y, Koets A, Weber M, Bakker D, Stabel J, Whitlock RH, Louzoun Y.

Vet Res. 2015 Jun 19;46:66. doi: 10.1186/s13567-015-0188-x.


Longitudinal data collection of Mycobacterium avium subspecies Paratuberculosis infections in dairy herds: the value of precise field data.

Schukken YH, Whitlock RH, Wolfgang D, Grohn Y, Beaver A, VanKessel J, Zurakowski M, Mitchell R.

Vet Res. 2015 Jun 19;46:65. doi: 10.1186/s13567-015-0187-y.


Back to the real world: connecting models with data.

Mitchell RM, Whitlock RH, Gröhn YT, Schukken YH.

Prev Vet Med. 2015 Feb 1;118(2-3):215-25. doi: 10.1016/j.prevetmed.2014.12.009. Epub 2014 Dec 22.


Cost-effectiveness of diagnostic strategies to identify Mycobacterium avium subspecies paratuberculosis super-shedder cows in a large dairy herd using antibody enzyme-linked immunosorbent assays, quantitative real-time polymerase chain reaction, and bacterial culture.

Aly SS, Anderson RJ, Whitlock RH, Fyock TL, McAdams SC, Byrem TM, Jiang J, Adaska JM, Gardner IA.

J Vet Diagn Invest. 2012 Sep;24(5):821-32. doi: 10.1177/1040638712452107. Epub 2012 Jul 17.


Quantitative real-time PCR for detection of the neurotoxin gene of Clostridium botulinum type B in equine and bovine samples.

Johnson AL, Sweeney RW, McAdams SC, Whitlock RH.

Vet J. 2012 Oct;194(1):118-20. doi: 10.1016/j.tvjl.2012.03.018. Epub 2012 Apr 24.


Meta-analysis of two genome-wide association studies of bovine paratuberculosis.

Minozzi G, Williams JL, Stella A, Strozzi F, Luini M, Settles ML, Taylor JF, Whitlock RH, Zanella R, Neibergs HL.

PLoS One. 2012;7(3):e32578. doi: 10.1371/journal.pone.0032578. Epub 2012 Mar 2.


Low rate of detectable in utero transmission of Mycobacterium avium subspecies paratuberculosis in a dairy herd with a low prevalence of Johne's disease.

Adaska JM, Whitlock RH.

J Vet Diagn Invest. 2012 Jan;24(1):153-5. doi: 10.1177/1040638711425947. Epub 2011 Dec 6.


Evolution of the bovine TLR gene family and member associations with Mycobacterium avium subspecies paratuberculosis infection.

Fisher CA, Bhattarai EK, Osterstock JB, Dowd SE, Seabury PM, Vikram M, Whitlock RH, Schukken YH, Schnabel RD, Taylor JF, Womack JE, Seabury CM.

PLoS One. 2011;6(11):e27744. doi: 10.1371/journal.pone.0027744. Epub 2011 Nov 30. Erratum in: PLoS One. 2012;7(1):doi/10.1371/annotation/429afd9a-2892-47ac-a403-008496b2e8db. PLoS One. 2012;7(1):doi/10.1371/annotation/63a06de9-db62-4651-87f3-a5fd431dcd80. PLoS One. 2012;7(2):doi/10.1371/annotation/a84f0490-55cd-4b42-8b2e-72661fabfc22.


Treatment and chemoprophylaxis for paratuberculosis.

Fecteau ME, Whitlock RH.

Vet Clin North Am Food Anim Pract. 2011 Nov;27(3):547-57, v. doi: 10.1016/j.cvfa.2011.07.002. Review.


Evaluation of the in vitro activity of gallium nitrate against Mycobacterium avium subsp paratuberculosis.

Fecteau ME, Fyock TL, McAdams SC, Boston RC, Whitlock RH, Sweeney RW.

Am J Vet Res. 2011 Sep;72(9):1243-6. doi: 10.2460/ajvr.72.9.1243.


Culture phenotypes of genomically and geographically diverse Mycobacterium avium subsp. paratuberculosis isolates from different hosts.

Whittington RJ, Marsh IB, Saunders V, Grant IR, Juste R, Sevilla IA, Manning EJ, Whitlock RH.

J Clin Microbiol. 2011 May;49(5):1822-30. doi: 10.1128/JCM.00210-11. Epub 2011 Mar 23.


Application of a peptide-mediated magnetic separation-phage assay for detection of viable Mycobacterium avium subsp. paratuberculosis to bovine bulk tank milk and feces samples.

Foddai A, Strain S, Whitlock RH, Elliott CT, Grant IR.

J Clin Microbiol. 2011 May;49(5):2017-9. doi: 10.1128/JCM.00429-11. Epub 2011 Mar 16.


Molecular epidemiology of Mycobacterium avium subsp. paratuberculosis in a longitudinal study of three dairy herds.

Pradhan AK, Mitchell RM, Kramer AJ, Zurakowski MJ, Fyock TL, Whitlock RH, Smith JM, Hovingh E, Van Kessel JA, Karns JS, Schukken YH.

J Clin Microbiol. 2011 Mar;49(3):893-901. doi: 10.1128/JCM.01107-10. Epub 2011 Jan 5.


Development of a predictive model for detection of Mycobacterium avium subsp. paratuberculosis in faeces by quantitative real time PCR.

Kralik P, Slana I, Kralova A, Babak V, Whitlock RH, Pavlik I.

Vet Microbiol. 2011 Apr 21;149(1-2):133-8. doi: 10.1016/j.vetmic.2010.10.009. Epub 2010 Oct 21.


Correlation between Herrold egg yolk medium culture and real-time quantitative polymerase chain reaction results for Mycobacterium avium subspecies paratuberculosis in pooled fecal and environmental samples.

Aly SS, Mangold BL, Whitlock RH, Sweeney RW, Anderson RJ, Jiang J, Schukken YH, Hovingh E, Wolfgang D, Van Kessel JA, Karns JS, Lombard JE, Smith JM, Gardner IA.

J Vet Diagn Invest. 2010 Sep;22(5):677-83.


GSEA-SNP identifies genes associated with Johne's disease in cattle.

Neibergs HL, Settles ML, Whitlock RH, Taylor JF.

Mamm Genome. 2010 Aug;21(7-8):419-25. doi: 10.1007/s00335-010-9278-2. Epub 2010 Aug 13.


Absorbed EVELISA: a diagnostic test with improved specificity for Johne's disease in cattle.

Scott MC, Bannantine JP, Kaneko Y, Branscum AJ, Whitlock RH, Mori Y, Speer CA, Eda S.

Foodborne Pathog Dis. 2010 Nov;7(11):1291-6. doi: 10.1089/fpd.2010.0541. Epub 2010 Aug 12.


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