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Items: 6

1.

A Critical Review of Animal Models Used in Acute Myeloid Leukemia Pathophysiology.

Skayneh H, Jishi B, Hleihel R, Hamieh M, Darwiche N, Bazarbachi A, El Sabban M, El Hajj H.

Genes (Basel). 2019 Aug 13;10(8). pii: E614. doi: 10.3390/genes10080614. Review.

2.

The HTLV-1 oncoprotein Tax is modified by the ubiquitin related modifier 1 (Urm1).

Hleihel R, Khoshnood B, Dacklin I, Omran H, Mouawad C, Dassouki Z, El-Sabban M, Shirinian M, Grabbe C, Bazarbachi A.

Retrovirology. 2018 Apr 17;15(1):33. doi: 10.1186/s12977-018-0415-4.

3.

Mouse Models That Enhanced Our Understanding of Adult T Cell Leukemia.

Moodad S, Akkouche A, Hleihel R, Darwiche N, El-Sabban M, Bazarbachi A, El Hajj H.

Front Microbiol. 2018 Mar 28;9:558. doi: 10.3389/fmicb.2018.00558. eCollection 2018. Review.

4.

Antitumor Effect of the Atypical Retinoid ST1926 in Acute Myeloid Leukemia and Nanoparticle Formulation Prolongs Lifespan and Reduces Tumor Burden of Xenograft Mice.

El-Houjeiri L, Saad W, Hayar B, Aouad P, Tawil N, Abdel-Samad R, Hleihel R, Hamie M, Mancinelli A, Pisano C, El Hajj H, Darwiche N.

Mol Cancer Ther. 2017 Oct;16(10):2047-2057. doi: 10.1158/1535-7163.MCT-16-0785. Epub 2017 Jun 15.

5.

Imidazoquinoxaline derivative EAPB0503: A promising drug targeting mutant nucleophosmin 1 in acute myeloid leukemia.

Nabbouh AI, Hleihel RS, Saliba JL, Karam MM, Hamie MH, Wu HJM, Berthier CP, Tawil NM, Bonnet PA, Deleuze-Masquefa C, El Hajj HA.

Cancer. 2017 May 1;123(9):1662-1673. doi: 10.1002/cncr.30515. Epub 2017 Jan 5.

6.

Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells.

El Hajj H, Dassouki Z, Berthier C, Raffoux E, Ades L, Legrand O, Hleihel R, Sahin U, Tawil N, Salameh A, Zibara K, Darwiche N, Mohty M, Dombret H, Fenaux P, de Thé H, Bazarbachi A.

Blood. 2015 May 28;125(22):3447-54. doi: 10.1182/blood-2014-11-612416. Epub 2015 Mar 23.

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