Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 33


Schrödinger's pipeline and the outsourcing of pharmaceutical innovation.

McMeekin P, Lendrem DW, Lendrem BC, Pratt AG, Peck R, Isaacs JD, Jones D.

Drug Discov Today. 2019 Dec 10. pii: S1359-6446(19)30457-X. doi: 10.1016/j.drudis.2019.11.015. [Epub ahead of print]


Organs-on-Chips in Clinical Pharmacology: Putting the Patient Into the Center of Treatment Selection and Drug Development.

Peck RW, Hinojosa CD, Hamilton GA.

Clin Pharmacol Ther. 2020 Jan;107(1):181-185. doi: 10.1002/cpt.1688. Epub 2019 Nov 23. Review.


Development and Implementation of Electronic Health Record-Integrated Model-Informed Clinical Decision Support Tools for the Precision Dosing of Drugs.

Vinks AA, Peck RW, Neely M, Mould DR.

Clin Pharmacol Ther. 2020 Jan;107(1):129-135. doi: 10.1002/cpt.1679. Epub 2019 Nov 25. Review.


A Framework Proposal to Follow-Up on Preclinical Convulsive Signals of a New Molecular Entity in First-in-Human Studies Using Electroencephalographic Monitoring.

Abt M, Dinklo T, Rothfuss A, Husar E, Dannecker R, Kallivroussis K, Peck R, Doessegger L, Wandel C.

Clin Pharmacol Ther. 2019 Nov;106(5):968-980. doi: 10.1002/cpt.1455. Epub 2019 May 31. Review.


Models and Machines: How Deep Learning Will Take Clinical Pharmacology to the Next Level.

Hutchinson L, Steiert B, Soubret A, Wagg J, Phipps A, Peck R, Charoin JE, Ribba B.

CPT Pharmacometrics Syst Pharmacol. 2019 Mar;8(3):131-134. doi: 10.1002/psp4.12377. Epub 2019 Feb 3.


Toward Dynamic Prescribing Information: Codevelopment of Companion Model-Informed Precision Dosing Tools in Drug Development.

Polasek TM, Rayner CR, Peck RW, Rowland A, Kimko H, Rostami-Hodjegan A.

Clin Pharmacol Drug Dev. 2019 May;8(4):418-425. doi: 10.1002/cpdd.638. Epub 2018 Nov 30.


Use of quantitative clinical pharmacology to improve early clinical development success in neurodegenerative diseases.

Geerts H, Gieschke R, Peck R.

Expert Rev Clin Pharmacol. 2018 Aug;11(8):789-795. doi: 10.1080/17512433.2018.1501555. Epub 2018 Aug 3. Review.


An Updated Review of Iclaprim: A Potent and Rapidly Bactericidal Antibiotic for the Treatment of Skin and Skin Structure Infections and Nosocomial Pneumonia Caused by Gram-Positive Including Multidrug-Resistant Bacteria.

Huang DB, Strader CD, MacDonald JS, VanArendonk M, Peck R, Holland T.

Open Forum Infect Dis. 2018 Jan 6;5(2):ofy003. doi: 10.1093/ofid/ofy003. eCollection 2018 Feb. Review.


Precision Medicine Is Not Just Genomics: The Right Dose for Every Patient.

Peck RW.

Annu Rev Pharmacol Toxicol. 2018 Jan 6;58:105-122. doi: 10.1146/annurev-pharmtox-010617-052446. Epub 2017 Sep 27. Review.


The pharmaceutical industry needs more clinical pharmacologists.

Peck R.

Br J Clin Pharmacol. 2017 Nov;83(11):2343-2346. doi: 10.1111/bcp.13370. Epub 2017 Aug 16. No abstract available.


Graphic Warning Labels and the Cost Savings from Reduced Smoking among Pregnant Women.

Tauras JA, Peck RM, Cheng KW, Chaloupka FJ.

Int J Environ Res Public Health. 2017 Feb 8;14(2). pii: E164. doi: 10.3390/ijerph14020164.


Erratum to: Clinical trial considerations on male contraception and collection of pregnancy information from female partner: update.

Banholzer ML, Wandel C, Barrow P, Mannino M, Schmitt G, Guérard M, Müller L, Greig G, Amemiya K, Peck R, Singer T, Doessegger L.

Clin Transl Med. 2016 Dec;5(1):30. doi: 10.1186/s40169-016-0115-4. Epub 2016 Aug 12. No abstract available.


Clinical trial considerations on male contraception and collection of pregnancy information from female partner: update.

Banholzer ML, Wandel C, Barrow P, Mannino M, Schmitt G, Guérard M, Müller L, Greig G, Amemiya K, Peck R, Singer T, Doessegger L.

Clin Transl Med. 2016 Dec;5(1):23. doi: 10.1186/s40169-016-0103-8. Epub 2016 Jul 25. Erratum in: Clin Transl Med. 2016 Dec;5(1):30.


Combining 'Bottom-Up' and 'Top-Down' Methods to Assess Ethnic Difference in Clearance: Bitopertin as an Example.

Feng S, Shi J, Parrott N, Hu P, Weber C, Martin-Facklam M, Saito T, Peck R.

Clin Pharmacokinet. 2016 Jul;55(7):823-832. doi: 10.1007/s40262-015-0356-1.


The right dose for every patient: a key step for precision medicine.

Peck RW.

Nat Rev Drug Discov. 2016 Mar;15(3):145-6. doi: 10.1038/nrd.2015.22. Epub 2015 Dec 16.


Why is it hard to terminate failing projects in pharmaceutical R&D?

Peck RW, Lendrem DW, Grant I, Lendrem BC, Isaacs JD.

Nat Rev Drug Discov. 2015 Oct;14(10):663-4. doi: 10.1038/nrd4725. Epub 2015 Aug 21.


Clinical pharmacology characterization of RG7112, an MDM2 antagonist, in patients with advanced solid tumors.

Patnaik A, Tolcher A, Beeram M, Nemunaitis J, Weiss GJ, Bhalla K, Agrawal M, Nichols G, Middleton S, Beryozkina A, Sarapa N, Peck R, Zhi J.

Cancer Chemother Pharmacol. 2015 Sep;76(3):587-95. doi: 10.1007/s00280-015-2830-8. Epub 2015 Jul 26.


Progression-seeking bias and rational optimism in research and development.

Lendrem DW, Lendrem BC, Peck RW, Senn SC, Day S, Isaacs JD.

Nat Rev Drug Discov. 2015 Mar;14(3):219-21. doi: 10.1038/nrd4320-c1. Epub 2015 Feb 6. No abstract available.


National and state cost savings associated with prohibiting smoking in subsidized and public housing in the United States.

King BA, Peck RM, Babb SD.

Prev Chronic Dis. 2014 Oct 2;11:E171. doi: 10.5888/pcd11.140222.


Bayesian adaptive designs in single ascending dose trials in healthy volunteers.

Guédé D, Reigner B, Vandenhende F, Derks M, Beyer U, Jordan P, Worth E, Diack C, Frey N, Peck R.

Br J Clin Pharmacol. 2014 Aug;78(2):393-400. doi: 10.1111/bcp.12344.

Supplemental Content

Loading ...
Support Center