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Items: 1 to 20 of 70

1.

Empagliflozin restores the integrity of the endothelial glycocalyx in vitro.

Cooper S, Teoh H, Campeau MA, Verma S, Leask RL.

Mol Cell Biochem. 2019 Sep;459(1-2):121-130. doi: 10.1007/s11010-019-03555-2. Epub 2019 May 24.

PMID:
31127491
2.

Designing Green Plasticizers: Linear Alkyl Diol Dibenzoate Plasticizers and a Thermally Reversible Plasticizer.

Erythropel HC, Börmann A, Nicell JA, Leask RL, Maric M.

Polymers (Basel). 2018 Jun 9;10(6). pii: E646. doi: 10.3390/polym10060646.

3.

How Green is Your Plasticizer?

Jamarani R, Erythropel HC, Nicell JA, Leask RL, Marić M.

Polymers (Basel). 2018 Jul 28;10(8). pii: E834. doi: 10.3390/polym10080834. Review.

4.

Dispersible hydrogel force sensors reveal patterns of solid mechanical stress in multicellular spheroid cultures.

Lee W, Kalashnikov N, Mok S, Halaoui R, Kuzmin E, Putnam AJ, Takayama S, Park M, McCaffrey L, Zhao R, Leask RL, Moraes C.

Nat Commun. 2019 Jan 11;10(1):144. doi: 10.1038/s41467-018-07967-4.

5.

Increased MMP activity in curved geometries disrupts the endothelial cell glycocalyx creating a proinflammatory environment.

Cooper S, Emmott A, McDonald KK, Campeau MA, Leask RL.

PLoS One. 2018 Aug 23;13(8):e0202526. doi: 10.1371/journal.pone.0202526. eCollection 2018.

6.

Transesophageal echocardiographic strain imaging predicts aortic biomechanics: Beyond diameter.

Emmott A, Alzahrani H, Alreshidan M, Therrien J, Leask RL, Lachapelle K.

J Thorac Cardiovasc Surg. 2018 Aug;156(2):503-512.e1. doi: 10.1016/j.jtcvs.2018.01.107. Epub 2018 Mar 11.

PMID:
29627182
7.

3D printing materials and their use in medical education: a review of current technology and trends for the future.

Garcia J, Yang Z, Mongrain R, Leask RL, Lachapelle K.

BMJ Simul Technol Enhanc Learn. 2018 Jan;4(1):27-40. doi: 10.1136/bmjstel-2017-000234. Epub 2017 Oct 21.

8.

Investigation on the Regional Loss Factor and Its Anisotropy for Aortic Aneurysms.

Shahmansouri N, Alreshidan M, Emmott A, Lachapelle K, El-Hamamsy I, Cartier R, Leask RL, Mongrain R.

Materials (Basel). 2016 Oct 26;9(11). pii: E867. doi: 10.3390/ma9110867.

9.

Histopathological and biomechanical properties of the aortic wall in 2 patients with chronic type A aortic dissection.

Emmott A, El-Hamamsy I, Leask RL.

Cardiovasc Pathol. 2017 Jul - Aug;29:48-52. doi: 10.1016/j.carpath.2017.05.006. Epub 2017 May 30.

PMID:
28601673
10.

Stenosis Hemodynamics Disrupt the Endothelial Cell Glycocalyx by MMP Activity Creating a Proinflammatory Environment.

Cooper S, McDonald K, Burkat D, Leask RL.

Ann Biomed Eng. 2017 Sep;45(9):2234-2243. doi: 10.1007/s10439-017-1846-0. Epub 2017 May 4.

PMID:
28474270
11.

Blood flow can signal during angiogenesis not only through mechanotransduction, but also by affecting growth factor distribution.

Ghaffari S, Leask RL, Jones EAV.

Angiogenesis. 2017 Aug;20(3):373-384. doi: 10.1007/s10456-017-9553-x. Epub 2017 Apr 3.

PMID:
28374123
12.

Obtaining the biomechanical behavior of ascending aortic aneurysm via the use of novel speckle tracking echocardiography.

Alreshidan M, Shahmansouri N, Chung J, Lash V, Emmott A, Leask RL, Lachapelle K.

J Thorac Cardiovasc Surg. 2017 Apr;153(4):781-788. doi: 10.1016/j.jtcvs.2016.11.056. Epub 2016 Dec 20.

13.

Glycocalyx Degradation Induces a Proinflammatory Phenotype and Increased Leukocyte Adhesion in Cultured Endothelial Cells under Flow.

McDonald KK, Cooper S, Danielzak L, Leask RL.

PLoS One. 2016 Dec 1;11(12):e0167576. doi: 10.1371/journal.pone.0167576. eCollection 2016.

14.

Loss of mechanical directional dependency of the ascending aorta with severe medial degeneration.

Chung J, Lachapelle K, Cartier R, Mongrain R, Leask RL.

Cardiovasc Pathol. 2017 Jan - Feb;26:45-50. doi: 10.1016/j.carpath.2016.11.001. Epub 2016 Nov 15.

PMID:
27888778
15.

Evaluating ascending aortic aneurysm tissue toughness: Dependence on collagen and elastin contents.

Shahmansouri N, Alreshidan M, Emmott A, Lachapelle K, Cartier R, Leask RL, Mongrain R.

J Mech Behav Biomed Mater. 2016 Dec;64:262-71. doi: 10.1016/j.jmbbm.2016.08.006. Epub 2016 Aug 6.

PMID:
27526037
16.

Effect of in vivo flow dynamics on angiogenesis by computational modeling.

Ghaffari S, Leask RL, Jones EA.

Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:961-4. doi: 10.1109/EMBC.2015.7318523.

PMID:
26736423
17.

Biomechanics of the Ascending Thoracic Aorta: A Clinical Perspective on Engineering Data.

Emmott A, Garcia J, Chung J, Lachapelle K, El-Hamamsy I, Mongrain R, Cartier R, Leask RL.

Can J Cardiol. 2016 Jan;32(1):35-47. doi: 10.1016/j.cjca.2015.10.015. Epub 2015 Oct 23. Review.

PMID:
26724509
18.

Flow dynamics control the location of sprouting and direct elongation during developmental angiogenesis.

Ghaffari S, Leask RL, Jones EA.

Development. 2015 Dec 1;142(23):4151-7. doi: 10.1242/dev.128058. Epub 2015 Nov 9.

19.

Making it stick: the role of structural design in implantable technologies.

Lee W, Leask RL, Moraes C.

Integr Biol (Camb). 2015 Nov;7(11):1335-8. doi: 10.1039/c5ib90041g.

PMID:
26446511
20.

Simultaneous imaging of blood flow dynamics and vascular remodelling during development.

Ghaffari S, Leask RL, Jones EA.

Development. 2015 Dec 1;142(23):4158-67. doi: 10.1242/dev.127019. Epub 2015 Oct 6.

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