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Items: 1 to 20 of 262


Biomarkers in the path from cellular senescence to frailty.

Zampino M, Ferrucci L, Semba RD.

Exp Gerontol. 2019 Oct 31;129:110750. doi: 10.1016/j.exger.2019.110750. [Epub ahead of print] Review. No abstract available.


Discovery proteomics in aging human skeletal muscle finds change in spliceosome, immunity, proteostasis and mitochondria.

Ubaida-Mohien C, Lyashkov A, Gonzalez-Freire M, Tharakan R, Shardell M, Moaddel R, Semba RD, Chia CW, Gorospe M, Sen R, Ferrucci L.

Elife. 2019 Oct 23;8. pii: e49874. doi: 10.7554/eLife.49874.


Serum Amino Acid Concentrations in Infants from Malawi are Associated with Linear Growth.

Ordiz MI, Semba RD, Moaddel R, Rolle-Kampczyk U, von Bergen M, Herberth G, Khadeer M, Röder S, Manary MJ.

Curr Dev Nutr. 2019 Aug 29;3(10):nzz100. doi: 10.1093/cdn/nzz100. eCollection 2019 Oct.


Tetra-linoleoyl cardiolipin depletion plays a major role in the pathogenesis of sarcopenia.

Semba RD, Moaddel R, Zhang P, Ramsden CE, Ferrucci L.

Med Hypotheses. 2019 Jun;127:142-149. doi: 10.1016/j.mehy.2019.04.015. Epub 2019 Apr 17.


Elevated Plasma Growth and Differentiation Factor-15 is Associated with Slower Gait Speed and Lower Physical Performance in Healthy Community-Dwelling Adults.

Semba RD, Gonzalez-Freire M, Tanaka T, Biancotto A, Zhang P, Shardell M, Moaddel R, Ferrucci L; CHI Consortium.

J Gerontol A Biol Sci Med Sci. 2019 Mar 15. pii: glz071. doi: 10.1093/gerona/glz071. [Epub ahead of print]


Low plasma lysophosphatidylcholines are associated with impaired mitochondrial oxidative capacity in adults in the Baltimore Longitudinal Study of Aging.

Semba RD, Zhang P, Adelnia F, Sun K, Gonzalez-Freire M, Salem N Jr, Brennan N, Spencer RG, Fishbein K, Khadeer M, Shardell M, Moaddel R, Ferrucci L.

Aging Cell. 2019 Apr;18(2):e12915. doi: 10.1111/acel.12915. Epub 2019 Feb 4.


Serum lipids in adults with late age-related macular degeneration: a case-control study.

Semba RD, Moaddel R, Cotch MF, Jonasson F, Eiriksdottir G, Harris TB, Launer LJ, Sun K, Klein R, Schaumberg DA, Jónsson P, Gudnason V, Ferrucci L.

Lipids Health Dis. 2019 Jan 8;18(1):7. doi: 10.1186/s12944-018-0954-7.


Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography-Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults.

Semba RD, Zhang P, Zhu M, Fabbri E, Gonzalez-Freire M, Carlson OD, Moaddel R, Tanaka T, Egan JM, Ferrucci L.

J Gerontol A Biol Sci Med Sci. 2019 Jan 1;74(1):129-136. doi: 10.1093/gerona/gly255.


Association of Fibroblast Growth Factor-23 (FGF-23) With Incident Frailty in HIV-Infected and HIV-Uninfected Individuals.

Wang R, Shlipak MG, Ix JH, Brown TT, Jacobson LP, Palella FJ Jr, Lake JE, Koletar SL, Semba RD, Estrella MM.

J Acquir Immune Defic Syndr. 2019 Jan 1;80(1):118-125. doi: 10.1097/QAI.0000000000001868.


Inflammation and micronutrient biomarkers predict clinical HIV treatment failure and incident active TB in HIV-infected adults: a case-control study.

Shivakoti R, Gupte N, Tripathy S, Poongulali S, Kanyama C, Berendes S, Cardoso SW, Santos BR, La Rosa A, Mwelase N, Pillay S, Samaneka W, Riviere C, Sugandhavesa P, Bollinger RC, Balagopal A, Semba RD, Christian P, Campbell TB, Gupta A; NWCS 319 and PEARLS Study Team.

BMC Med. 2018 Sep 24;16(1):161. doi: 10.1186/s12916-018-1150-3.


Plasma proteomic signature of age in healthy humans.

Tanaka T, Biancotto A, Moaddel R, Moore AZ, Gonzalez-Freire M, Aon MA, Candia J, Zhang P, Cheung F, Fantoni G; CHI consortium, Semba RD, Ferrucci L.

Aging Cell. 2018 Oct;17(5):e12799. doi: 10.1111/acel.12799. Epub 2018 Jul 11.


Altered Plasma Amino Acids and Lipids Associated With Abnormal Glucose Metabolism and Insulin Resistance in Older Adults.

Semba RD, Gonzalez-Freire M, Moaddel R, Sun K, Fabbri E, Zhang P, Carlson OD, Khadeer M, Chia CW, Salem N Jr, Ferrucci L.

J Clin Endocrinol Metab. 2018 Sep 1;103(9):3331-3339. doi: 10.1210/jc.2018-00480.


Effect of baseline micronutrient and inflammation status on CD4 recovery post-cART initiation in the multinational PEARLS trial.

Shivakoti R, Ewald ER, Gupte N, Yang WT, Kanyama C, Cardoso SW, Santos B, Supparatpinyo K, Badal-Faesen S, Lama JR, Lalloo U, Zulu F, Pawar JS, Riviere C, Kumarasamy N, Hakim J, Pollard R, Detrick B, Balagopal A, Asmuth DM, Semba RD, Campbell TB, Golub J, Gupta A; NWCS 319 and ACTG PEARLS Study Team.

Clin Nutr. 2019 Jun;38(3):1303-1309. doi: 10.1016/j.clnu.2018.05.014. Epub 2018 May 29.


Targeted Metabolomics Shows Low Plasma Lysophosphatidylcholine 18:2 Predicts Greater Decline of Gait Speed in Older Adults: The Baltimore Longitudinal Study of Aging.

Gonzalez-Freire M, Moaddel R, Sun K, Fabbri E, Zhang P, Khadeer M, Salem N Jr, Ferrucci L, Semba RD.

J Gerontol A Biol Sci Med Sci. 2019 Jan 1;74(1):62-67. doi: 10.1093/gerona/gly100.


Kenneth John Carpenter, Ph.D. (1923-2016).

Semba RD.

J Nutr. 2018 Feb 1;148(2):167-169. doi: 10.1093/jn/nxx014. No abstract available.


The Human Eye Proteome Project: Updates on an Emerging Proteome.

Ahmad MT, Zhang P, Dufresne C, Ferrucci L, Semba RD.

Proteomics. 2018 Mar;18(5-6):e1700394. doi: 10.1002/pmic.201700394. Review.


A proteomic approach to understanding the pathogenesis of idiopathic macular hole formation.

Zhang P, Zhu M, Zhao Y, Qian J, Dufresne C, Turner R, Semba RD, Solomon SD.

Clin Proteomics. 2017 Nov 15;14:37. doi: 10.1186/s12014-017-9172-y. eCollection 2017.


Low serum ω-3 and ω-6 polyunsaturated fatty acids and other metabolites are associated with poor linear growth in young children from rural Malawi.

Semba RD, Trehan I, Li X, Salem N Jr, Moaddel R, Ordiz MI, Maleta KM, Kraemer K, Manary MJ.

Am J Clin Nutr. 2017 Dec;106(6):1490-1499. doi: 10.3945/ajcn.117.164384. Epub 2017 Oct 25.


Plasma Klotho and Frailty in Older Adults: Findings From the InCHIANTI Study.

Shardell M, Semba RD, Kalyani RR, Bandinelli S, Prather AA, Chia CW, Ferrucci L.

J Gerontol A Biol Sci Med Sci. 2019 Jun 18;74(7):1052-1057. doi: 10.1093/gerona/glx202.


A targeted proteomic assay for the measurement of plasma proteoforms related to human aging phenotypes.

Semba RD, Zhang P, Zhu M, Fabbri E, Gonzalez-Freire M, Moaddel R, Geng-Spyropoulos M, Ferrucci L.

Proteomics. 2017 Aug;17(15-16). doi: 10.1002/pmic.201600232.

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