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Items: 1 to 20 of 76

1.

Ligand-Induced G-Quadruplex Polymorphism: A DNA Nanodevice for Label-Free Aptasensor Platforms.

Deore PS, Gray MD, Chung AJ, Manderville RA.

J Am Chem Soc. 2019 Sep 11;141(36):14288-14297. doi: 10.1021/jacs.9b06533. Epub 2019 Sep 3.

PMID:
31436972
2.
3.

Molecular Dynamics Study of One-Base Deletion Duplexes Containing the Major DNA Adduct Formed by Ochratoxin A: Effects of Sequence Context and Adduct Ionization State on Lesion Site Structure and Mutagenicity.

Kathuria P, Singh P, Sharma P, Manderville RA, Wetmore SD.

J Phys Chem B. 2019 Aug 15;123(32):6980-6989. doi: 10.1021/acs.jpcb.9b06489. Epub 2019 Aug 2.

PMID:
31311268
4.

A coumarin-hemicyanine hybrid as a ratiometric fluorescent sensor of microenvironment proticity.

Deore PS, Coman DS, Manderville RA.

Chem Commun (Camb). 2019 Mar 19;55(24):3540-3543. doi: 10.1039/c8cc10132a.

PMID:
30839953
5.

Adduct Fluorescence as a Tool to Decipher Sequence Impact on Frameshift Mutations Mediated by a C-Linked C8-Biphenyl-Guanine Lesion.

Berger FD, Manderville RA, Sturla SJ.

Chem Res Toxicol. 2019 Apr 15;32(4):784-791. doi: 10.1021/acs.chemrestox.9b00016. Epub 2019 Mar 18.

PMID:
30785283
6.

Acceptor Influence on Thiolate Sensing by Hemicyanine Dyes.

Chung AJ, Deore PS, Al-Abdul-Wahid S, Aboelnga MM, Wetmore SD, Manderville RA.

J Org Chem. 2019 Feb 15;84(4):2261-2268. doi: 10.1021/acs.joc.9b00066. Epub 2019 Feb 1.

PMID:
30664354
7.

A 5'-BODIPY End-label for Monitoring DNA Duplex-Quadruplex Exchange.

Deore PS, Soldatov DV, Manderville RA.

Sci Rep. 2018 Nov 15;8(1):16874. doi: 10.1038/s41598-018-35352-0.

8.

DNA Aptamer-Target Binding Motif Revealed Using a Fluorescent Guanine Probe: Implications for Food Toxin Detection.

Fadock KL, Manderville RA.

ACS Omega. 2017 Aug 31;2(8):4955-4963. doi: 10.1021/acsomega.7b00782. Epub 2017 Aug 25.

9.
10.

Manipulation of a DNA aptamer-protein binding site through arylation of internal guanine residues.

Van Riesen AJ, Fadock KL, Deore PS, Desoky A, Manderville RA, Sowlati-Hashjin S, Wetmore SD.

Org Biomol Chem. 2018 May 23;16(20):3831-3840. doi: 10.1039/c8ob00704g.

PMID:
29745412
11.

Conformational Preference and Fluorescence Response of a C-Linked C8-Biphenyl-Guanine Lesion in the NarI Mutational Hotspot: Evidence for Enhanced Syn Adduct Formation.

Berger FD, Sturla SJ, Kung RW, Montina T, Wetmore SD, Manderville RA.

Chem Res Toxicol. 2018 Jan 16;31(1):37-47. doi: 10.1021/acs.chemrestox.7b00266. Epub 2017 Dec 14.

PMID:
29186656
12.

Mutagenicity of Ochratoxin A: Role for a Carbon-Linked C8-Deoxyguanosine Adduct?

Manderville RA, Wetmore SD.

J Agric Food Chem. 2017 Aug 23;65(33):7097-7105. doi: 10.1021/acs.jafc.6b03897. Epub 2016 Nov 15. Review.

PMID:
28830149
13.

Molecular Modeling of the Major DNA Adduct Formed from Food Mutagen Ochratoxin A in NarI Two-Base Deletion Duplexes: Impact of Sequence Context and Adduct Ionization on Conformational Preference and Mutagenicity.

Kathuria P, Sharma P, Manderville RA, Wetmore SD.

Chem Res Toxicol. 2017 Aug 21;30(8):1582-1591. doi: 10.1021/acs.chemrestox.7b00103. Epub 2017 Aug 8.

PMID:
28719194
14.

Toxic mechanisms of microcystins in mammals.

McLellan NL, Manderville RA.

Toxicol Res (Camb). 2017 Apr 24;6(4):391-405. doi: 10.1039/c7tx00043j. eCollection 2017 Jul 1. Review.

15.

Understanding the Mutagenicity of O-Linked and C-Linked Guanine DNA Adducts: A Combined Experimental and Computational Approach.

Manderville RA, Wetmore SD.

Chem Res Toxicol. 2017 Jan 17;30(1):177-188. doi: 10.1021/acs.chemrestox.6b00323. Epub 2016 Nov 1.

PMID:
27768845
16.

A Simple Molecular Rotor for Defining Nucleoside Environment within a DNA Aptamer-Protein Complex.

Cservenyi TZ, Van Riesen AJ, Berger FD, Desoky A, Manderville RA.

ACS Chem Biol. 2016 Sep 16;11(9):2576-82. doi: 10.1021/acschembio.6b00437. Epub 2016 Jul 27.

PMID:
27447371
17.

An internal charge transfer-DNA platform for fluorescence sensing of divalent metal ions.

Blanchard DJ, Manderville RA.

Chem Commun (Camb). 2016 Jul 21;52(61):9586-8. doi: 10.1039/c6cc04613d.

PMID:
27399260
18.

C-Linked 8-aryl guanine nucleobase adducts: biological outcomes and utility as fluorescent probes.

Manderville RA, Wetmore SD.

Chem Sci. 2016 Jun 1;7(6):3482-3493. doi: 10.1039/c6sc00053c. Epub 2016 Feb 24. Review.

19.

Optimization of fluorescent 8-heteroaryl-guanine probes for monitoring protein-mediated duplex → G-quadruplex exchange.

Fadock KL, Manderville RA, Sharma P, Wetmore SD.

Org Biomol Chem. 2016 May 11;14(19):4409-19. doi: 10.1039/c6ob00474a.

PMID:
27040462
20.

Dual fluorescent deoxyguanosine mimics for FRET detection of G-quadruplex folding.

Blanchard DJ, Cservenyi TZ, Manderville RA.

Chem Commun (Camb). 2015 Dec 7;51(94):16829-31. doi: 10.1039/c5cc07154b. Epub 2015 Oct 5.

PMID:
26435483

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