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Items: 18


Environmental Conditions May Shape the Patterns of Genomic Variations in Leishmania panamensis.

Restrepo CM, Llanes A, Cedeño EM, Chang JH, Álvarez J, Ríos M, Penagos H, Suárez JA, Lleonart R.

Genes (Basel). 2019 Oct 24;10(11). pii: E838. doi: 10.3390/genes10110838.


Hexahydropyrrolo[2,3-b]indole Compounds as Potential Therapeutics for Alzheimer's Disease.

Doens D, Valdés-Tresanco ME, Vasquez V, Carreira MB, De La Guardia Y, Stephens DE, Nguyen VD, Nguyen VT, Gu J, Hegde ML, Larionov OV, Valiente PA, Lleonart R, Fernández PL.

ACS Chem Neurosci. 2019 Oct 16;10(10):4250-4263. doi: 10.1021/acschemneuro.9b00297. Epub 2019 Oct 7.


VianniaTopes: a database of predicted immunogenic peptides for Leishmania (Viannia) species.

Llanes A, Restrepo CM, Lleonart R.

Database (Oxford). 2018 Jan 1;2018. doi: 10.1093/database/bay111.


Antiviral Activity of Novel Quinoline Derivatives against Dengue Virus Serotype 2.

de la Guardia C, Stephens DE, Dang HT, Quijada M, Larionov OV, Lleonart R.

Molecules. 2018 Mar 16;23(3). pii: E672. doi: 10.3390/molecules23030672.


Phage-Displayed Peptides Selected to Bind Envelope Glycoprotein Show Antiviral Activity against Dengue Virus Serotype 2.

de la Guardia C, Quijada M, Lleonart R.

Adv Virol. 2017;2017:1827341. doi: 10.1155/2017/1827341. Epub 2017 Sep 10.


Use of AFLP for the study of eukaryotic pathogens affecting humans.

Restrepo CM, Llanes A, Lleonart R.

Infect Genet Evol. 2018 Sep;63:360-369. doi: 10.1016/j.meegid.2017.09.017. Epub 2017 Sep 19. Review.


Identification of Inhibitors of CD36-Amyloid Beta Binding as Potential Agents for Alzheimer's Disease.

Doens D, Valiente PA, Mfuh AM, X T Vo A, Tristan A, Carreño L, Quijada M, Nguyen VT, Perry G, Larionov OV, Lleonart R, Fernández PL.

ACS Chem Neurosci. 2017 Jun 21;8(6):1232-1241. doi: 10.1021/acschemneuro.6b00386. Epub 2017 Feb 15.


Insights into the structural patterns of the antileishmanial activity of bi- and tricyclic N-heterocycles.

Herrera L, Stephens DE, D'Avila A, George KG, Arman H, Zhang Y, Perry G, Lleonart R, Larionov OV, Fernández PL.

Org Biomol Chem. 2016 Aug 7;14(29):7053-60. doi: 10.1039/c6ob01149g. Epub 2016 Jul 4.


Genome-wide discovery and development of polymorphic microsatellites from Leishmania panamensis parasites circulating in central Panama.

Restrepo CM, Llanes A, De La Guardia C, Lleonart R.

Parasit Vectors. 2015 Oct 12;8:527. doi: 10.1186/s13071-015-1153-2.


The genome of Leishmania panamensis: insights into genomics of the L. (Viannia) subgenus.

Llanes A, Restrepo CM, Del Vecchio G, Anguizola FJ, Lleonart R.

Sci Rep. 2015 Feb 24;5:8550. doi: 10.1038/srep08550.


Progress in the identification of dengue virus entry/fusion inhibitors.

De La Guardia C, Lleonart R.

Biomed Res Int. 2014;2014:825039. doi: 10.1155/2014/825039. Epub 2014 Jul 24. Review.


A pseudopterane diterpene isolated from the octocoral Pseudopterogorgia acerosa inhibits the inflammatory response mediated by TLR-ligands and TNF-alpha in macrophages.

González Y, Doens D, Santamaría R, Ramos M, Restrepo CM, Barros de Arruda L, Lleonart R, Gutiérrez M, Fernández PL.

PLoS One. 2013 Dec 16;8(12):e84107. doi: 10.1371/journal.pone.0084107. eCollection 2013.


AFLP polymorphisms allow high resolution genetic analysis of American Tegumentary Leishmaniasis agents circulating in Panama and other members of the Leishmania genus.

Restrepo CM, De La Guardia C, Sousa OE, Calzada JE, Fernández PL, Lleonart R.

PLoS One. 2013 Sep 9;8(9):e73177. doi: 10.1371/journal.pone.0073177. eCollection 2013.


Two initial vaccinations with the Bm86-based Gavacplus vaccine against Rhipicephalus (Boophilus) microplus induce similar reproductive suppression to three initial vaccinations under production conditions.

Vargas M, Montero C, Sánchez D, Pérez D, Valdés M, Alfonso A, Joglar M, Machado H, Rodríguez E, Méndez L, Lleonart R, Suárez M, Fernández E, Estrada MP, Rodríguez-Mallón A, Farnós O.

BMC Vet Res. 2010 Sep 16;6:43. doi: 10.1186/1746-6148-6-43.


Biochemical and structural characterization of RHDV capsid protein variants produced in Pichia pastoris: advantages for immunization strategies and vaccine implementation.

Farnós O, Fernández E, Chiong M, Parra F, Joglar M, Méndez L, Rodríguez E, Moya G, Rodríguez D, Lleonart R, González EM, Alonso A, Alfonso P, Suárez M, Rodríguez MP, Toledo JR.

Antiviral Res. 2009 Jan;81(1):25-36. doi: 10.1016/j.antiviral.2008.08.007. Epub 2008 Sep 25.


The recombinant rabbit hemorrhagic disease virus VP60 protein obtained from Pichia pastoris induces a strong humoral and cell-mediated immune response following intranasal immunization in mice.

Farnós O, Rodríguez M, Chiong M, Parra F, Boué O, Lorenzo N, Colás M, Lleonart R.

Vet Microbiol. 2006 May 31;114(3-4):187-95. Epub 2005 Dec 27.


High-level expression and immunogenic properties of the recombinant rabbit hemorrhagic disease virus VP60 capsid protein obtained in Pichia pastoris.

Farnós O, Boué O, Parra F, Martín-Alonso JM, Valdés O, Joglar M, Navea L, Naranjo P, Lleonart R.

J Biotechnol. 2005 May 25;117(3):215-24.


Genetic structure of a Cuban population based on nine short tandem repeat loci.

Carpio Y, Sainz de la Peña MV, Santiesteban M, Amaro F, Ferreira R, Lleonart R.

Int J Legal Med. 2005 May;119(3):137-41. Epub 2005 Feb 15.


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