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A Diet Rich in Fish Oil and Leucine Ameliorates Hypercalcemia in Tumour-Induced Cachectic Mice.

Plas RLC, Poland M, Faber J, Argilès J, van Dijk M, Laviano A, Meijerink J, Witkamp RF, van Helvoort A, van Norren K.

Int J Mol Sci. 2019 Oct 9;20(20). pii: E4978. doi: 10.3390/ijms20204978.


N-Eicosapentaenoyl Dopamine, A Conjugate of Dopamine and Eicosapentaenoic Acid (EPA), Exerts Anti-inflammatory Properties in Mouse and Human Macrophages.

Augimeri G, Plastina P, Gionfriddo G, Rovito D, Giordano C, Fazio A, Barone I, Catalano S, Andò S, Bonofiglio D, Meijerink J, Witkamp R.

Nutrients. 2019 Sep 18;11(9). pii: E2247. doi: 10.3390/nu11092247.


Novel COX-2 products of n-3 polyunsaturated fatty acid-ethanolamine-conjugates identified in RAW264.7 macrophages.

de Bus I, Zuilhof H, Witkamp R, Balvers M, Albada B.

J Lipid Res. 2019 Nov;60(11):1829-1840. doi: 10.1194/jlr.M094235. Epub 2019 Aug 27.


Anti-inflammatory nutrition with high protein attenuates cardiac and skeletal muscle alterations in a pulmonary arterial hypertension model.

Vinke P, Bowen TS, Boekschoten MV, Witkamp RF, Adams V, van Norren K.

Sci Rep. 2019 Jul 15;9(1):10160. doi: 10.1038/s41598-019-46331-4.


The Effect of Calcium Buffering and Calcium Sensor Type on the Sensitivity of an Array-Based Bitter Receptor Screening Assay.

Roelse M, Wehrens R, Henquet MG, Witkamp RF, Hall RD, Jongsma MA.

Chem Senses. 2019 Sep 7;44(7):497-505. doi: 10.1093/chemse/bjz044.


The role of n-3 PUFA-derived fatty acid derivatives and their oxygenated metabolites in the modulation of inflammation.

de Bus I, Witkamp R, Zuilhof H, Albada B, Balvers M.

Prostaglandins Other Lipid Mediat. 2019 Oct;144:106351. doi: 10.1016/j.prostaglandins.2019.106351. Epub 2019 Jun 28. Review.


Capsaicin Analogues Derived from n-3 Polyunsaturated Fatty Acids (PUFAs) Reduce Inflammatory Activity of Macrophages and Stimulate Insulin Secretion by β-Cells In Vitro.

Cione E, Plastina P, Pingitore A, Perri M, Caroleo MC, Fazio A, Witkamp R, Meijerink J.

Nutrients. 2019 Apr 24;11(4). pii: E915. doi: 10.3390/nu11040915.


Identification of hydroxytyrosyl oleate, a derivative of hydroxytyrosol with anti-inflammatory properties, in olive oil by-products.

Plastina P, Benincasa C, Perri E, Fazio A, Augimeri G, Poland M, Witkamp R, Meijerink J.

Food Chem. 2019 May 1;279:105-113. doi: 10.1016/j.foodchem.2018.12.007. Epub 2018 Dec 6.


Plasma citrulline concentration, a marker for intestinal functionality, reflects exercise intensity in healthy young men.

Kartaram S, Mensink M, Teunis M, Schoen E, Witte G, Janssen Duijghuijsen L, Verschuren M, Mohrmann K, M'Rabet L, Knipping K, Wittink H, van Helvoort A, Garssen J, Witkamp R, Pieters R, van Norren K.

Clin Nutr. 2019 Oct;38(5):2251-2258. doi: 10.1016/j.clnu.2018.09.029. Epub 2018 Sep 28.


Release of Major Peanut Allergens from Their Matrix under Various pH and Simulated Saliva Conditions-Ara h2 and Ara h6 Are Readily Bio-Accessible.

Koppelman SJ, Smits M, Tomassen M, de Jong GAH, Baumert J, Taylor SL, Witkamp R, Veldman RJ, Pieters R, Wichers H.

Nutrients. 2018 Sep 11;10(9). pii: E1281. doi: 10.3390/nu10091281.


Mitochondrial dynamics in cancer-induced cachexia.

van der Ende M, Grefte S, Plas R, Meijerink J, Witkamp RF, Keijer J, van Norren K.

Biochim Biophys Acta Rev Cancer. 2018 Dec;1870(2):137-150. doi: 10.1016/j.bbcan.2018.07.008. Epub 2018 Jul 29. Review.


Let thy food be thy medicine….when possible.

Witkamp RF, van Norren K.

Eur J Pharmacol. 2018 Oct 5;836:102-114. doi: 10.1016/j.ejphar.2018.06.026. Epub 2018 Jun 21.


In Vitro Anti-Inflammatory and Radical Scavenging Properties of Chinotto (Citrus myrtifolia Raf.) Essential Oils.

Plastina P, Apriantini A, Meijerink J, Witkamp R, Gabriele B, Fazio A.

Nutrients. 2018 Jun 18;10(6). pii: E783. doi: 10.3390/nu10060783.


Increasing quality of life in pulmonary arterial hypertension: is there a role for nutrition?

Vinke P, Jansen SM, Witkamp RF, van Norren K.

Heart Fail Rev. 2018 Sep;23(5):711-722. doi: 10.1007/s10741-018-9717-9. Review.


Associations of hyperosmolar medications administered via nasogastric or nasoduodenal tubes and feeding adequacy, food intolerance and gastrointestinal complications amongst critically ill patients: A retrospective study.

Wesselink E, Koekkoek KWAC, Looijen M, van Blokland DA, Witkamp RF, van Zanten ARH.

Clin Nutr ESPEN. 2018 Jun;25:78-86. doi: 10.1016/j.clnesp.2018.04.001. Epub 2018 Apr 17.


Calcium Imaging of GPCR Activation Using Arrays of Reverse Transfected HEK293 Cells in a Microfluidic System.

Roelse M, Henquet MGL, Verhoeven HA, de Ruijter NCA, Wehrens R, van Lenthe MS, Witkamp RF, Hall RD, Jongsma MA.

Sensors (Basel). 2018 Feb 16;18(2). pii: E602. doi: 10.3390/s18020602.


The role of fatty acids and their endocannabinoid-like derivatives in the molecular regulation of appetite.

Witkamp RF.

Mol Aspects Med. 2018 Dec;64:45-67. doi: 10.1016/j.mam.2018.01.002. Epub 2018 Jan 19. Review.


Explorative Placebo-Controlled Double-Blind Intervention Study with Low Doses of Inhaled Δ9-Tetrahydrocannabinol and Cannabidiol Reveals No Effect on Sweet Taste Intensity Perception and Liking in Humans.

de Bruijn SEM, de Graaf C, Witkamp RF, Jager G.

Cannabis Cannabinoid Res. 2017 Jun 1;2(1):114-122. doi: 10.1089/can.2017.0018. eCollection 2017.


Public health relevance of drug-nutrition interactions.

Péter S, Navis G, de Borst MH, von Schacky C, van Orten-Luiten ACB, Zhernakova A, Witkamp RF, Janse A, Weber P, Bakker SJL, Eggersdorfer M.

Eur J Nutr. 2017 Aug;56(Suppl 2):23-36. doi: 10.1007/s00394-017-1510-3.


The role of hypothalamic inflammation, the hypothalamic-pituitary-adrenal axis and serotonin in the cancer anorexia-cachexia syndrome.

van Norren K, Dwarkasing JT, Witkamp RF.

Curr Opin Clin Nutr Metab Care. 2017 Sep;20(5):396-401. doi: 10.1097/MCO.0000000000000401. Review.


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