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Severity Assessment in animal based research.

Bleich A, Bankstahl M, Jirkof P, Prins JB, Tolba RH.

Lab Anim. 2020 Feb;54(1):16. doi: 10.1177/0023677219898105. No abstract available.


All You Can Feed: Some Comments on Production of Mouse Diets Used in Biomedical Research with Special Emphasis on Non-Alcoholic Fatty Liver Disease Research.

Weiskirchen S, Weiper K, Tolba RH, Weiskirchen R.

Nutrients. 2020 Jan 7;12(1). pii: E163. doi: 10.3390/nu12010163. Review.


Oxygen inhalation improves postoperative survival in ketamine-xylazine anaesthetised rats: An observational study.

Mechelinck M, Kupp C, Krüger JC, Habigt MA, Helmedag MJ, Tolba RH, Rossaint R, Hein M.

PLoS One. 2019 Dec 13;14(12):e0226430. doi: 10.1371/journal.pone.0226430. eCollection 2019.


Semi-automated generation of pictures for the Mouse Grimace Scale: A multi-laboratory analysis (Part 2).

Ernst L, Kopaczka M, Schulz M, Talbot SR, Struve B, Häger C, Bleich A, Durst M, Jirkof P, Arras M, van Dijk RM, Miljanovic N, Potschka H, Merhof D, Tolba RH.

Lab Anim. 2020 Feb;54(1):92-98. doi: 10.1177/0023677219881664. Epub 2019 Oct 29.


Performance of severity parameters to detect chemotherapy-induced pain and distress in mice.

Rix A, Drude N, Mrugalla A, Mottaghy FM, Tolba RH, Kiessling F.

Lab Anim. 2019 Oct 29:23677219883327. doi: 10.1177/0023677219883327. [Epub ahead of print]


Improvement of the Mouse Grimace Scale set-up for implementing a semi-automated Mouse Grimace Scale scoring (Part 1).

Ernst L, Kopaczka M, Schulz M, Talbot SR, Zieglowski L, Meyer M, Bruch S, Merhof D, Tolba RH.

Lab Anim. 2020 Feb;54(1):83-91. doi: 10.1177/0023677219881655. Epub 2019 Oct 24.


A Dual Protective Effect of Intestinal Remote Ischemic Conditioning in a Rat Model of Total Hepatic Ischemia.

Czigany Z, Hata K, Lai W, Schwandt T, Yamamoto Y, Uemoto S, Tolba RH.

J Clin Med. 2019 Sep 26;8(10). pii: E1546. doi: 10.3390/jcm8101546.


Cold Preflush of Porcine Kidney Grafts Prior to Normothermic Machine Perfusion Aggravates Ischemia Reperfusion Injury.

Fabry G, Doorschodt BM, Grzanna T, Boor P, Elliott A, Stollenwerk A, Tolba RH, Rossaint R, Bleilevens C.

Sci Rep. 2019 Sep 25;9(1):13897. doi: 10.1038/s41598-019-50101-7.


Design of a joint research data platform: A use case for severity assessment.

Talbot SR, Bruch S, Kießling F, Marschollek M, Jandric B, Tolba RH, Bleich A.

Lab Anim. 2020 Feb;54(1):33-39. doi: 10.1177/0023677219872228. Epub 2019 Sep 5.


Influence of Vitamin C on Antioxidant Capacity of In Vitro Perfused Porcine Kidneys.

Bleilevens C, Doorschodt BM, Fechter T, Grzanna T, Theißen A, Liehn EA, Breuer T, Tolba RH, Rossaint R, Stoppe C, Boor P, Hill A, Fabry G.

Nutrients. 2019 Aug 1;11(8). pii: E1774. doi: 10.3390/nu11081774.


In vivo endothelialization and neointimal hyperplasia assessment after angioplasty of sheep carotid artery with a novel polycarbonate polyurethane patch.

Jalaie H, Steitz J, Afify M, Barbati ME, Hoeft K, Assar MAM, Hermanns-Sachweh B, Tolba RH, Jacobs MJ, Schleimer K.

J Biomater Appl. 2019 Aug;34(2):208-218. doi: 10.1177/0885328219849368. Epub 2019 May 14. No abstract available.


The Impact of a Nitric Oxide Synthase Inhibitor (L-NAME) on Ischemia⁻Reperfusion Injury of Cholestatic Livers by Pringle Maneuver and Liver Resection after Bile Duct Ligation in Rats.

Iwasaki J, Afify M, Bleilevens C, Klinge U, Weiskirchen R, Steitz J, Vogt M, Yagi S, Nagai K, Uemoto S, Tolba RH.

Int J Mol Sci. 2019 Apr 29;20(9). pii: E2114. doi: 10.3390/ijms20092114.


The Role of Macrophage Migration Inhibitory Factor in Remote Ischemic Conditioning Induced Hepatoprotection in a Rodent Model of Liver Transplantation.

Emontzpohl C, Stoppe C, Theißen A, Beckers C, Neumann UP, Lurje G, Ju C, Bernhagen J, Tolba RH, Czigany Z.

Shock. 2019 Nov;52(5):e124-e134. doi: 10.1097/SHK.0000000000001307.


Donor liver quality after hypovolemic shock and venous systemic oxygen persufflation in an experimental animal model.

Jafari A, Matthaei H, Branchi V, Bölke E, Tolba RH, Kalff JC, Manekeller S.

Eur J Med Res. 2018 Oct 23;23(1):51. doi: 10.1186/s40001-018-0346-5.


Early local microcirculation is improved after intramedullary nailing in comparison to external fixation in a porcine model with a femur fracture.

Kalbas Y, Qiao Z, Horst K, Teuben M, Tolba RH, Hildebrand F, Pape HC, Pfeifer R; TREAT Research Group.

Eur J Trauma Emerg Surg. 2018 Oct;44(5):689-696. doi: 10.1007/s00068-018-0991-y. Epub 2018 Aug 22.


Machine perfusion for liver transplantation in the era of marginal organs-New kids on the block.

Czigany Z, Lurje I, Tolba RH, Neumann UP, Tacke F, Lurje G.

Liver Int. 2019 Feb;39(2):228-249. doi: 10.1111/liv.13946. Epub 2018 Sep 29. Review.


Assessment of Plasma Coagulation on Liver Tissue in a Large Animal Model In Vivo.

Glowka TR, Paschenda P, Czaplik M, Kalff JC, Tolba RH.

J Vis Exp. 2018 Aug 4;(138). doi: 10.3791/57355.


Hydrogen Flush After Cold Storage as a New End-Ischemic Ex Vivo Treatment for Liver Grafts Against Ischemia/Reperfusion Injury.

Tamaki I, Hata K, Okamura Y, Nigmet Y, Hirao H, Kubota T, Inamoto O, Kusakabe J, Goto T, Tajima T, Yoshikawa J, Tanaka H, Tsuruyama T, Tolba RH, Uemoto S.

Liver Transpl. 2018 Nov;24(11):1589-1602. doi: 10.1002/lt.25326.


Sheep models for evaluation of novel patch and prosthesis material in vascular surgery: tips and tricks to avoid possible pitfalls.

Schleimer K, Jalaie H, Afify M, Woitok A, Barbati ME, Hoeft K, Jacobs M, Tolba RH, Steitz J.

Acta Vet Scand. 2018 Jul 5;60(1):42. doi: 10.1186/s13028-018-0397-1.


Limb remote ischemic conditioning of the recipient protects the liver in a rat model of arterialized orthotopic liver transplantation.

Czigany Z, Bleilevens C, Beckers C, Stoppe C, Möhring M, Fülöp A, Szijarto A, Lurje G, Neumann UP, Tolba RH.

PLoS One. 2018 Apr 4;13(4):e0195507. doi: 10.1371/journal.pone.0195507. eCollection 2018.

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