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Items: 1 to 20 of 25


Viability Assessment Following Anticancer Treatment Requires Single-Cell Visualization.

Mirzayans R, Andrais B, Murray D.

Cancers (Basel). 2018 Aug 1;10(8). pii: E255. doi: 10.3390/cancers10080255.


Defenses against Pro-oxidant Forces - Maintenance of Cellular and Genomic Integrity and Longevity.

Murray D, Mirzayans R, McBride WH.

Radiat Res. 2018 Oct;190(4):331-349. doi: 10.1667/RR15101.1. Epub 2018 Jul 24.


Roles of Polyploid/Multinucleated Giant Cancer Cells in Metastasis and Disease Relapse Following Anticancer Treatment.

Mirzayans R, Andrais B, Murray D.

Cancers (Basel). 2018 Apr 15;10(4). pii: E118. doi: 10.3390/cancers10040118.


Do Multiwell Plate High Throughput Assays Measure Loss of Cell Viability Following Exposure to Genotoxic Agents?

Mirzayans R, Andrais B, Murray D.

Int J Mol Sci. 2017 Aug 2;18(8). pii: E1679. doi: 10.3390/ijms18081679.


Impact of Premature Senescence on Radiosensitivity Measured by High Throughput Cell-Based Assays.

Mirzayans R, Andrais B, Murray D.

Int J Mol Sci. 2017 Jul 6;18(7). pii: E1460. doi: 10.3390/ijms18071460.


Significance of Wild-Type p53 Signaling in Suppressing Apoptosis in Response to Chemical Genotoxic Agents: Impact on Chemotherapy Outcome.

Mirzayans R, Andrais B, Kumar P, Murray D.

Int J Mol Sci. 2017 Apr 28;18(5). pii: E928. doi: 10.3390/ijms18050928. Review.


Multinucleated Giant Cancer Cells Produced in Response to Ionizing Radiation Retain Viability and Replicate Their Genome.

Mirzayans R, Andrais B, Scott A, Wang YW, Kumar P, Murray D.

Int J Mol Sci. 2017 Feb 8;18(2). pii: E360. doi: 10.3390/ijms18020360.


The Growing Complexity of Cancer Cell Response to DNA-Damaging Agents: Caspase 3 Mediates Cell Death or Survival?

Mirzayans R, Andrais B, Kumar P, Murray D.

Int J Mol Sci. 2016 May 11;17(5). pii: E708. doi: 10.3390/ijms17050708. Review.


OCT4A and the DNA damage response.

Murray D, Mirzayans R.

Cell Cycle. 2015;14(18):2871-2. doi: 10.1080/15384101.2015.1069507. Epub 2015 Jul 15. No abstract available.


Spontaneous γH2AX Foci in Human Solid Tumor-Derived Cell Lines in Relation to p21WAF1 and WIP1 Expression.

Mirzayans R, Andrais B, Scott A, Wang YW, Weiss RH, Murray D.

Int J Mol Sci. 2015 May 20;16(5):11609-28. doi: 10.3390/ijms160511609.


Characterization of the apoptotic response induced by the cyanine dye D112: a potentially selective anti-cancer compound.

Yang N, Gilman P, Mirzayans R, Sun X, Touret N, Weinfeld M, Goping IS.

PLoS One. 2015 Apr 30;10(4):e0125381. doi: 10.1371/journal.pone.0125381. eCollection 2015.


Modeling familial cancer with induced pluripotent stem cells.

Lee DF, Su J, Kim HS, Chang B, Papatsenko D, Zhao R, Yuan Y, Gingold J, Xia W, Darr H, Mirzayans R, Hung MC, Schaniel C, Lemischka IR.

Cell. 2015 Apr 9;161(2):240-54. doi: 10.1016/j.cell.2015.02.045.


Spatial and temporal distribution of γH2AX fluorescence in human cell cultures following synchrotron-generated X-ray microbeams: lack of correlation between persistent γH2AX foci and apoptosis.

Anderson DL, Mirzayans R, Andrais B, Siegbahn EA, Fallone BG, Warkentin B.

J Synchrotron Radiat. 2014 Jul;21(Pt 4):801-10. doi: 10.1107/S1600577514011424. Epub 2014 Jun 13.


Ionizing radiation-induced responses in human cells with differing TP53 status.

Mirzayans R, Andrais B, Scott A, Wang YW, Murray D.

Int J Mol Sci. 2013 Nov 13;14(11):22409-35. doi: 10.3390/ijms141122409. Review.


Role of p16(INK4A) in Replicative Senescence and DNA Damage-Induced Premature Senescence in p53-Deficient Human Cells.

Mirzayans R, Andrais B, Hansen G, Murray D.

Biochem Res Int. 2012;2012:951574. doi: 10.1155/2012/951574. Epub 2012 Aug 13.


New insights into p53 signaling and cancer cell response to DNA damage: implications for cancer therapy.

Mirzayans R, Andrais B, Scott A, Murray D.

J Biomed Biotechnol. 2012;2012:170325. doi: 10.1155/2012/170325. Epub 2012 Jul 15. Review.


A requirement for polymerized actin in DNA double-strand break repair.

Andrin C, McDonald D, Attwood KM, Rodrigue A, Ghosh S, Mirzayans R, Masson JY, Dellaire G, Hendzel MJ.

Nucleus. 2012 Jul 1;3(4):384-95. Epub 2012 Jun 12.


Single-cell analysis of p16(INK4a) and p21(WAF1) expression suggests distinct mechanisms of senescence in normal human and Li-Fraumeni Syndrome fibroblasts.

Mirzayans R, Andrais B, Scott A, Paterson MC, Murray D.

J Cell Physiol. 2010 Apr;223(1):57-67. doi: 10.1002/jcp.22002.


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