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Items: 1 to 20 of 44


Enhanced IFN-γ, but not IL-2, response to Mycobacterium tuberculosis antigens in HIV/latent TB co-infected patients on long-term HAART.

Desalegn G, Tsegaye A, Gebreegziabiher D, Aseffa A, Howe R.

BMC Immunol. 2019 Oct 11;20(1):35. doi: 10.1186/s12865-019-0317-9.


CYP2D6 Genotype Predicts Plasma Concentrations of Tamoxifen Metabolites in Ethiopian Breast Cancer Patients.

Ahmed JH, Makonnen E, Fotoohi A, Aseffa A, Howe R, Aklillu E.

Cancers (Basel). 2019 Sep 12;11(9). pii: E1353. doi: 10.3390/cancers11091353.


CYP2J27 Genotype Predicts Risk of Chemotherapy-Induced Hematologic Toxicity and Reduced Relative Dose Intensity in Ethiopian Breast Cancer Patients.

Ahmed JH, Makonnen E, Yimer G, Seifu D, Bekele A, Assefa M, Aseffa A, Howe R, Fotoohi A, Hassan M, Aklillu E.

Front Pharmacol. 2019 May 14;10:481. doi: 10.3389/fphar.2019.00481. eCollection 2019.


Discovery and validation of a prognostic proteomic signature for tuberculosis progression: A prospective cohort study.

Penn-Nicholson A, Hraha T, Thompson EG, Sterling D, Mbandi SK, Wall KM, Fisher M, Suliman S, Shankar S, Hanekom WA, Janjic N, Hatherill M, Kaufmann SHE, Sutherland J, Walzl G, De Groote MA, Ochsner U, Zak DE, Scriba TJ; ACS and GC6–74 cohort study groups.

PLoS Med. 2019 Apr 16;16(4):e1002781. doi: 10.1371/journal.pmed.1002781. eCollection 2019 Apr. Erratum in: PLoS Med. 2019 Jul 18;16(7):e1002880.


Homing defects of B cells in HIV-1 infected children impair vaccination responses.

Bekele Y, Lemma M, Bobosha K, Yibeltal D, Nasi A, Gebre M, Nilsson A, Aseffa A, Howe R, Chiodi F.

Vaccine. 2019 Apr 17;37(17):2348-2355. doi: 10.1016/j.vaccine.2019.03.027. Epub 2019 Mar 23.


Vitamin D Status and Association of VDR Genetic Polymorphism to Risk of Breast Cancer in Ethiopia.

Ahmed JH, Makonnen E, Fotoohi A, Yimer G, Seifu D, Assefa M, Tigeneh W, Aseffa A, Howe R, Aklillu E.

Nutrients. 2019 Jan 29;11(2). pii: E289. doi: 10.3390/nu11020289.


Metabolite changes in blood predict the onset of tuberculosis.

Weiner J 3rd, Maertzdorf J, Sutherland JS, Duffy FJ, Thompson E, Suliman S, McEwen G, Thiel B, Parida SK, Zyla J, Hanekom WA, Mohney RP, Boom WH, Mayanja-Kizza H, Howe R, Dockrell HM, Ottenhoff THM, Scriba TJ, Zak DE, Walzl G, Kaufmann SHE; GC6-74 consortium.

Nat Commun. 2018 Dec 6;9(1):5208. doi: 10.1038/s41467-018-07635-7.


A study of clinical, hematological, and biochemical profiles of patients with dengue viral infections in Northwest Ethiopia: implications for patient management.

Ferede G, Tiruneh M, Abate E, Wondimeneh Y, Gadisa E, Howe R, Aseffa A, Tessema B.

BMC Infect Dis. 2018 Dec 4;18(1):616. doi: 10.1186/s12879-018-3557-z.


Phenotypic and functional heterogeneity of peripheral γδ T cells in pulmonary TB and HIV patients in Addis Ababa, Ethiopia.

Negash M, Tsegaye A, Wassie L, Howe R.

BMC Infect Dis. 2018 Sep 15;18(1):464. doi: 10.1186/s12879-018-3361-9.


Associations of gender and serum total cholesterol with CD4+ T cell count and HIV RNA load in antiretroviral-naïve individuals in Addis Ababa.

Adal M, Howe R, Kassa D, Aseffa A, Petros B.

BMC Public Health. 2018 Jul 31;18(1):943. doi: 10.1186/s12889-018-5852-4.


A serologic study of dengue in northwest Ethiopia: Suggesting preventive and control measures.

Ferede G, Tiruneh M, Abate E, Wondimeneh Y, Damtie D, Gadisa E, Howe R, Aseffa A, Tessema B.

PLoS Negl Trop Dis. 2018 May 31;12(5):e0006430. doi: 10.1371/journal.pntd.0006430. eCollection 2018 May.


Kidney Transplantation: The Challenge of Human Leukocyte Antigen and Its Therapeutic Strategies.

Alelign T, Ahmed MM, Bobosha K, Tadesse Y, Howe R, Petros B.

J Immunol Res. 2018 Mar 5;2018:5986740. doi: 10.1155/2018/5986740. eCollection 2018. Review.


Bacterial Profile, Antibacterial Resistance Pattern, and Associated Factors from Women Attending Postnatal Health Service at University of Gondar Teaching Hospital, Northwest Ethiopia.

Bitew Kifilie A, Dagnew M, Tegenie B, Yeshitela B, Howe R, Abate E.

Int J Microbiol. 2018 Feb 25;2018:3165391. doi: 10.1155/2018/3165391. eCollection 2018.


Malnutrition and lipid abnormalities in antiretroviral naïve HIV-infected adults in Addis Ababa: A cross-sectional study.

Adal M, Howe R, Kassa D, Aseffa A, Petros B.

PLoS One. 2018 Apr 19;13(4):e0195942. doi: 10.1371/journal.pone.0195942. eCollection 2018.


Four-gene Pan-African Blood Signature Predicts Progression to Tuberculosis.

Suliman S, Thompson E, Sutherland J, Weiner Rd J, Ota MOC, Shankar S, Penn-Nicholson A, Thiel B, Erasmus M, Maertzdorf J, Duffy FJ, Hill PC, Hughes EJ, Stanley K, Downing K, Fisher ML, Valvo J, Parida SK, van der Spuy G, Tromp G, Adetifa IMO, Donkor S, Howe R, Mayanja-Kizza H, Boom WH, Dockrell H, Ottenhoff THM, Hatherill M, Aderem A, Hanekom WA, Scriba TJ, Kaufmann SH, Zak DE, Walzl G; GC6-74 and ACS cohort study groups.

Am J Respir Crit Care Med. 2018 Apr 6. doi: 10.1164/rccm.201711-2340OC. [Epub ahead of print]


Africa-wide evaluation of host biomarkers in QuantiFERON supernatants for the diagnosis of pulmonary tuberculosis.

Chegou NN, Sutherland JS, Namuganga AR, Corstjens PL, Geluk A, Gebremichael G, Mendy J, Malherbe S, Stanley K, van der Spuy GD, Kriel M, Loxton AG, Kriel B, Simukonda F, Bekele Y, Sheehama JA, Nelongo J, van der Vyver M, Gebrexabher A, Hailu H, Esterhuyse MM, Rosenkrands I, Aagard C, Kidd M, Kassa D, Mihret A, Howe R, Cliff JM, Crampin AC, Mayanja-Kizza H, Kaufmann SHE, Dockrell HM, Ottenhoff THM, Walzl G; AE-TBC consortium.

Sci Rep. 2018 Feb 8;8(1):2675. doi: 10.1038/s41598-018-20855-7.


T-cell regulation in Erythema Nodosum Leprosum.

Negera E, Walker SL, Bobosha K, Howe R, Aseffa A, Dockrell HM, Lockwood DN.

PLoS Negl Trop Dis. 2017 Oct 9;11(10):e0006001. doi: 10.1371/journal.pntd.0006001. eCollection 2017 Oct.


New Insight into the Pathogenesis of Erythema Nodosum Leprosum: The Role of Activated Memory T-Cells.

Negera E, Bobosha K, Walker SL, Endale B, Howe R, Aseffa A, Dockrell HM, Lockwood DN.

Front Immunol. 2017 Sep 15;8:1149. doi: 10.3389/fimmu.2017.01149. eCollection 2017.

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