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Items: 14

1.

Crystal structure of Legionella pneumophila type IV secretion system effector LegAS4.

Son J, Jo CH, Murugan RN, Bang JK, Hwang KY, Lee WC.

Biochem Biophys Res Commun. 2015 Oct 2;465(4):817-24. doi: 10.1016/j.bbrc.2015.08.094. Epub 2015 Aug 24.

PMID:
26315269
2.

A new class of peptidomimetics targeting the polo-box domain of Polo-like kinase 1.

Ahn M, Han YH, Park JE, Kim S, Lee WC, Lee SJ, Gunasekaran P, Cheong C, Shin SY Sr, Kim HY, Ryu EK, Murugan RN, Kim NH, Bang JK.

J Med Chem. 2015 Jan 8;58(1):294-304. doi: 10.1021/jm501147g. Epub 2014 Nov 5.

PMID:
25347203
3.

Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis.

Park SY, Park JE, Kim TS, Kim JH, Kwak MJ, Ku B, Tian L, Murugan RN, Ahn M, Komiya S, Hojo H, Kim NH, Kim BY, Bang JK, Erikson RL, Lee KW, Kim SJ, Oh BH, Yang W, Lee KS.

Nat Struct Mol Biol. 2014 Aug;21(8):696-703. doi: 10.1038/nsmb.2846. Epub 2014 Jun 29.

4.

Poly-lysine peptidomimetics having potent antimicrobial activity without hemolytic activity.

Ahn M, Jacob B, Gunasekaran P, Murugan RN, Ryu EK, Lee GH, Hyun JK, Cheong C, Kim NH, Shin SY, Bang JK.

Amino Acids. 2014 Sep;46(9):2259-69. doi: 10.1007/s00726-014-1778-z. Epub 2014 Jun 25.

PMID:
24961649
5.

De novo design and synthesis of ultra-short peptidomimetic antibiotics having dual antimicrobial and anti-inflammatory activities.

Murugan RN, Jacob B, Ahn M, Hwang E, Sohn H, Park HN, Lee E, Seo JH, Cheong C, Nam KY, Hyun JK, Jeong KW, Kim Y, Shin SY, Bang JK.

PLoS One. 2013 Nov 26;8(11):e80025. doi: 10.1371/journal.pone.0080025. eCollection 2013.

6.

Hierarchical recruitment of Plk4 and regulation of centriole biogenesis by two centrosomal scaffolds, Cep192 and Cep152.

Kim TS, Park JE, Shukla A, Choi S, Murugan RN, Lee JH, Ahn M, Rhee K, Bang JK, Kim BY, Loncarek J, Erikson RL, Lee KS.

Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):E4849-57. doi: 10.1073/pnas.1319656110. Epub 2013 Nov 25.

7.

Exploring the binding nature of pyrrolidine pocket-dependent interactions in the polo-box domain of polo-like kinase 1.

Murugan RN, Ahn M, Lee WC, Kim HY, Song JH, Cheong C, Hwang E, Seo JH, Shin SY, Choi SH, Park JE, Bang JK.

PLoS One. 2013 Nov 6;8(11):e80043. doi: 10.1371/journal.pone.0080043. eCollection 2013.

8.

Discovery of novel histidine-derived lipo-amino acids: applied in the synthesis of ultra-short antimicrobial peptidomimetics having potent antimicrobial activity, salt resistance and protease stability.

Ahn M, Murugan RN, Jacob B, Hyun JK, Cheong C, Hwang E, Park HN, Seo JH, Srinivasrao G, Lee KS, Shin SY, Bang JK.

Eur J Med Chem. 2013 Oct;68:10-8. doi: 10.1016/j.ejmech.2013.07.008. Epub 2013 Jul 26.

PMID:
23933046
9.

Non hemolytic short peptidomimetics as a new class of potent and broad-spectrum antimicrobial agents.

Murugan RN, Jacob B, Kim EH, Ahn M, Sohn H, Seo JH, Cheong C, Hyun JK, Lee KS, Shin SY, Bang JK.

Bioorg Med Chem Lett. 2013 Aug 15;23(16):4633-6. doi: 10.1016/j.bmcl.2013.06.016. Epub 2013 Jun 14.

PMID:
23816372
10.

Antifreeze peptides and glycopeptides, and their derivatives: potential uses in biotechnology.

Bang JK, Lee JH, Murugan RN, Lee SG, Do H, Koh HY, Shim HE, Kim HC, Kim HJ.

Mar Drugs. 2013 Jun 10;11(6):2013-41. doi: 10.3390/md11062013. Review.

11.

Development of cyclic peptomer inhibitors targeting the polo-box domain of polo-like kinase 1.

Murugan RN, Park JE, Lim D, Ahn M, Cheong C, Kwon T, Nam KY, Choi SH, Kim BY, Yoon DY, Yaffe MB, Yu DY, Lee KS, Bang JK.

Bioorg Med Chem. 2013 May 1;21(9):2623-34. doi: 10.1016/j.bmc.2013.02.020. Epub 2013 Feb 27.

PMID:
23498919
12.

In vivo tumor imaging using polo-box domain of polo-like kinase 1 targeted peptide.

Kim SM, Yoon S, Choi N, Hong KS, Murugan RN, Cho G, Ryu EK.

Biomaterials. 2012 Oct;33(29):6915-25. doi: 10.1016/j.biomaterials.2012.06.046. Epub 2012 Jul 15.

PMID:
22795848
13.

Substitution of the GalNAc-α-O-Thr¹¹ residue in drosocin with O-linked glyco-peptoid residue: effect on antibacterial activity and conformational change.

Ahn M, Murugan RN, Nan YH, Cheong C, Sohn H, Kim EH, Hwang E, Ryu EK, Kang SW, Shin SY, Bang JK.

Bioorg Med Chem Lett. 2011 Oct 15;21(20):6148-53. doi: 10.1016/j.bmcl.2011.08.012. Epub 2011 Aug 19.

PMID:
21890357
14.

Plk1-targeted small molecule inhibitors: molecular basis for their potency and specificity.

Murugan RN, Park JE, Kim EH, Shin SY, Cheong C, Lee KS, Bang JK.

Mol Cells. 2011 Sep;32(3):209-20. doi: 10.1007/s10059-011-0126-3. Epub 2011 Jul 29. Review.

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