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Items: 11

1.

New pyrimidine-benzoxazole/benzimidazole hybrids: Synthesis, antioxidant, cytotoxic activity, in vitro cyclooxygenase and phospholipase A2-V inhibition.

Abdelgawad MA, Bakr RB, Ahmad W, Al-Sanea MM, Elshemy HAH.

Bioorg Chem. 2019 Nov;92:103218. doi: 10.1016/j.bioorg.2019.103218. Epub 2019 Aug 26.

PMID:
31536956
2.

Selective cyclooxygenase inhibition and ulcerogenic liability of some newly prepared anti-inflammatory agents having thiazolo[4,5-d]pyrimidine scaffold.

Bakr RB, Ghoneim AA, Azouz AA.

Bioorg Chem. 2019 Jul;88:102964. doi: 10.1016/j.bioorg.2019.102964. Epub 2019 Apr 30.

PMID:
31075742
3.

New advances in synthesis and clinical aspects of pyrazolo[3,4-d]pyrimidine scaffolds.

Abdellatif KRA, Bakr RB.

Bioorg Chem. 2018 Aug;78:341-357. doi: 10.1016/j.bioorg.2018.03.032. Epub 2018 Apr 3. Review.

PMID:
29627655
4.

Novel pyrimidine-pyridine hybrids: Synthesis, cyclooxygenase inhibition, anti-inflammatory activity and ulcerogenic liability.

Abdelgawad MA, Bakr RB, Azouz AA.

Bioorg Chem. 2018 Apr;77:339-348. doi: 10.1016/j.bioorg.2018.01.028. Epub 2018 Jan 31.

PMID:
29421710
5.

Discovery of a COX-2 selective inhibitor hit with anti-inflammatory activity and gastric ulcer protective effect.

Abdelgawad MA, Bakr RB, El-Gendy AO, Kamel GM, Azouz AA, Bukhari SNA.

Future Med Chem. 2017 Oct;9(16):1899-1912. doi: 10.4155/fmc-2017-0115. Epub 2017 Oct 27.

PMID:
29076755
6.

Design, synthesis and biological evaluation of some novel benzothiazole/benzoxazole and/or benzimidazole derivatives incorporating a pyrazole scaffold as antiproliferative agents.

Abdelgawad MA, Bakr RB, Omar HA.

Bioorg Chem. 2017 Oct;74:82-90. doi: 10.1016/j.bioorg.2017.07.007. Epub 2017 Jul 15.

PMID:
28772160
7.

Synthesis, EGFR Inhibition and Anti-cancer Activity of New 3,6-dimethyl-1-phenyl-4-(substituted-methoxy)pyrazolo[3,4-d] pyrimidine Derivatives.

Bakr RB, Mehany ABM, Abdellatif KRA.

Anticancer Agents Med Chem. 2017;17(10):1389-1400. doi: 10.2174/1872211311666170213105004.

PMID:
28270084
8.

Nitric Oxide-NASIDS Donor Prodrugs as Hybrid Safe Anti-inflammatory Agents.

Abdellatif KR, Abdelall EK, Bakr RB.

Curr Top Med Chem. 2017;17(8):941-955. doi: 10.2174/1568026616666160927153435. Review.

PMID:
27697053
9.

Synthesis, cyclooxygenase inhibition, anti-inflammatory evaluation and ulcerogenic liability of new 1-phenylpyrazolo[3,4-d]pyrimidine derivatives.

Bakr RB, Azouz AA, Abdellatif KR.

J Enzyme Inhib Med Chem. 2016;31(sup2):6-12. Epub 2016 May 22.

PMID:
27210522
10.

Design, synthesis and antitumor activity of novel pyrazolo[3,4-d]pyrimidine derivatives as EGFR-TK inhibitors.

Abdelgawad MA, Bakr RB, Alkhoja OA, Mohamed WR.

Bioorg Chem. 2016 Jun;66:88-96. doi: 10.1016/j.bioorg.2016.03.011. Epub 2016 Mar 24.

PMID:
27043178
11.

Synthesis and anticancer activity of some new pyrazolo[3,4-d]pyrimidin-4-one derivatives.

Abdellatif KR, Abdelall EK, Abdelgawad MA, Ahmed RR, Bakr RB.

Molecules. 2014 Mar 18;19(3):3297-309. doi: 10.3390/molecules19033297.

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