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Items: 1 to 20 of 60

1.

Conformational modifications induced by internal tandem duplications on the FLT3 kinase and juxtamembrane domains.

Todde G, Friedman R.

Phys Chem Chem Phys. 2019 Jul 25. doi: 10.1039/c9cp02938a. [Epub ahead of print]

PMID:
31342980
2.

Activation and Inactivation of the FLT3 Kinase: Pathway Intermediates and the Free Energy of Transition.

Todde G, Friedman R.

J Phys Chem B. 2019 Jul 5;123(26):5385-5394. doi: 10.1021/acs.jpcb.9b01567. Epub 2019 Jun 20.

PMID:
31244095
3.

Stochastic modelling of tyrosine kinase inhibitor rotation therapy in chronic myeloid leukaemia.

Lindström HJG, de Wijn AS, Friedman R.

BMC Cancer. 2019 May 28;19(1):508. doi: 10.1186/s12885-019-5690-5.

4.

Oxidative hotspots on actin promote skeletal muscle weakness in rheumatoid arthritis.

Steinz MM, Persson M, Aresh B, Olsson K, Cheng AJ, Ahlstrand E, Lilja M, Lundberg TR, Rullman E, Möller KÄ, Sandor K, Ajeganova S, Yamada T, Beard N, Karlsson BC, Tavi P, Kenne E, Svensson CI, Rassier DE, Karlsson R, Friedman R, Gustafsson T, Lanner JT.

JCI Insight. 2019 Mar 28;5. pii: 126347. doi: 10.1172/jci.insight.126347.

5.

Specific Ion and Concentration Effects in Acetate Solutions with Na+ , K+ and Cs.

Friedman R.

Chemphyschem. 2019 Apr 16;20(8):1006-1010. doi: 10.1002/cphc.201900163. Epub 2019 Mar 28.

PMID:
30817057
6.

The catalytic activity of Abl1 single and compound mutations: Implications for the mechanism of drug resistance mutations in chronic myeloid leukaemia.

Georgoulia PS, Todde G, Bjelic S, Friedman R.

Biochim Biophys Acta Gen Subj. 2019 Apr;1863(4):732-741. doi: 10.1016/j.bbagen.2019.01.011. Epub 2019 Jan 24.

PMID:
30684523
7.

Author Correction: Dilution of whisky - the molecular perspective.

Karlsson BCG, Friedman R.

Sci Rep. 2018 Nov 1;8(1):16448. doi: 10.1038/s41598-018-34169-1.

8.

Understanding Conformational Dynamics of Complex Lipid Mixtures Relevant to Biology.

Friedman R, Khalid S, Aponte-Santamaría C, Arutyunova E, Becker M, Boyd KJ, Christensen M, Coimbra JTS, Concilio S, Daday C, van Eerden FJ, Fernandes PA, Gräter F, Hakobyan D, Heuer A, Karathanou K, Keller F, Lemieux MJ, Marrink SJ, May ER, Mazumdar A, Naftalin R, Pickholz M, Piotto S, Pohl P, Quinn P, Ramos MJ, Schiøtt B, Sengupta D, Sessa L, Vanni S, Zeppelin T, Zoni V, Bondar AN, Domene C.

J Membr Biol. 2018 Dec;251(5-6):609-631. doi: 10.1007/s00232-018-0050-y. Epub 2018 Oct 22. Review.

9.

A computational study of hedgehog signalling involved in basal cell carcinoma reveals the potential and limitation of combination therapy.

Buetti-Dinh A, Jensen R, Friedman R.

BMC Cancer. 2018 May 18;18(1):569. doi: 10.1186/s12885-018-4451-1.

10.
11.

Membrane-Ion Interactions.

Friedman R.

J Membr Biol. 2018 Jun;251(3):453-460. doi: 10.1007/s00232-017-0010-y. Epub 2018 Jan 12.

12.

Computer simulations of alkali-acetate solutions: Accuracy of the forcefields in difference concentrations.

Ahlstrand E, Zukerman Schpector J, Friedman R.

J Chem Phys. 2017 Nov 21;147(19):194102. doi: 10.1063/1.4985919.

PMID:
29166095
13.

An interactive computer lab of the galvanic cell for students in biochemistry.

Ahlstrand E, Buetti-Dinh A, Friedman R.

Biochem Mol Biol Educ. 2018 Jan;46(1):58-65. doi: 10.1002/bmb.21091. Epub 2017 Nov 13.

PMID:
29131508
14.

Dilution of whisky - the molecular perspective.

Karlsson BCG, Friedman R.

Sci Rep. 2017 Aug 17;7(1):6489. doi: 10.1038/s41598-017-06423-5. Erratum in: Sci Rep. 2018 Nov 1;8(1):16448.

15.

The molecular mechanism behind resistance of the kinase FLT3 to the inhibitor quizartinib.

Friedman R.

Proteins. 2017 Nov;85(11):2143-2152. doi: 10.1002/prot.25368. Epub 2017 Aug 23.

PMID:
28799176
16.

Interaction Energies in Complexes of Zn and Amino Acids: A Comparison of Ab Initio and Force Field Based Calculations.

Ahlstrand E, Hermansson K, Friedman R.

J Phys Chem A. 2017 Apr 6;121(13):2643-2654. doi: 10.1021/acs.jpca.6b12969. Epub 2017 Mar 24.

PMID:
28272891
17.

Palbociclib can overcome mutations in cyclin dependent kinase 6 that break hydrogen bonds between the drug and the protein.

Hernandez Maganhi S, Jensen P, Caracelli I, Zukerman Schpector J, Fröhling S, Friedman R.

Protein Sci. 2017 Apr;26(4):870-879. doi: 10.1002/pro.3135. Epub 2017 Mar 6.

18.

Sensitivity Analysis of the NPM-ALK Signalling Network Reveals Important Pathways for Anaplastic Large Cell Lymphoma Combination Therapy.

Buetti-Dinh A, O'Hare T, Friedman R.

PLoS One. 2016 Sep 26;11(9):e0163011. doi: 10.1371/journal.pone.0163011. eCollection 2016.

19.

Biological Membranes in Extreme Conditions: Anionic Tetraether Lipid Membranes and Their Interactions with Sodium and Potassium.

Pineda De Castro LF, Dopson M, Friedman R.

J Phys Chem B. 2016 Oct 20;120(41):10628-10634. doi: 10.1021/acs.jpcb.6b06206. Epub 2016 Oct 7.

PMID:
27668511
20.

Transcriptomic analysis reveals how a lack of potassium ions increases Sulfolobus acidocaldarius sensitivity to pH changes.

Buetti-Dinh A, Dethlefsen O, Friedman R, Dopson M.

Microbiology. 2016 Aug;162(8):1422-34. doi: 10.1099/mic.0.000314. Epub 2016 May 26.

PMID:
27230583

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