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Items: 8


PI3K in stemness regulation: from development to cancer.

Madsen RR.

Biochem Soc Trans. 2020 Feb 28;48(1):301-315. doi: 10.1042/BST20190778.


Cracking the context-specific PI3K signaling code.

Madsen RR, Vanhaesebroeck B.

Sci Signal. 2020 Jan 7;13(613). pii: eaay2940. doi: 10.1126/scisignal.aay2940. Review.


Scientific impact and the quest for visibility.

Madsen RR.

FEBS J. 2019 Oct;286(20):3968-3974. doi: 10.1111/febs.15043. Epub 2019 Aug 29.


Epigenetic Regulation of Vascular Smooth Muscle Cells by Histone H3 Lysine 9 Dimethylation Attenuates Target Gene-Induction by Inflammatory Signaling.

Harman JL, Dobnikar L, Chappell J, Stokell BG, Dalby A, Foote K, Finigan A, Freire-Pritchett P, Taylor AL, Worssam MD, Madsen RR, Loche E, Uryga A, Bennett MR, Jørgensen HF.

Arterioscler Thromb Vasc Biol. 2019 Nov;39(11):2289-2302. doi: 10.1161/ATVBAHA.119.312765. Epub 2019 Aug 22.


Perspective: Potential Impact and Therapeutic Implications of Oncogenic PI3K Activation on Chromosomal Instability.

Vanhaesebroeck B, Bilanges B, Madsen RR, Dale KL, Lau E, Vladimirou E.

Biomolecules. 2019 Aug 1;9(8). pii: E331. doi: 10.3390/biom9080331. Review.


Luminescent peptide tagging enables efficient screening for CRISPR-mediated knock-in in human induced pluripotent stem cells.

Madsen RR, Semple RK.

Version 3. Wellcome Open Res. 2019 Jul 11 [revised 2019 Jan 1];4:37. doi: 10.12688/wellcomeopenres.15119.3. eCollection 2019.


Oncogenic PIK3CA promotes cellular stemness in an allele dose-dependent manner.

Madsen RR, Knox RG, Pearce W, Lopez S, Mahler-Araujo B, McGranahan N, Vanhaesebroeck B, Semple RK.

Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8380-8389. doi: 10.1073/pnas.1821093116. Epub 2019 Apr 4.


Cancer-Associated PIK3CA Mutations in Overgrowth Disorders.

Madsen RR, Vanhaesebroeck B, Semple RK.

Trends Mol Med. 2018 Oct;24(10):856-870. doi: 10.1016/j.molmed.2018.08.003. Epub 2018 Sep 6. Review.

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