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Items: 10


MSC.sTRAIL Has Better Efficacy than MSC.FL-TRAIL and in Combination with AKTi Blocks Pro-Metastatic Cytokine Production in Prostate Cancer Cells.

Mohr A, Chu T, Brooke GN, Zwacka RM.

Cancers (Basel). 2019 Apr 21;11(4). pii: E568. doi: 10.3390/cancers11040568.


Caspase-10: a molecular switch from cell-autonomous apoptosis to communal cell death in response to chemotherapeutic drug treatment.

Mohr A, Deedigan L, Jencz S, Mehrabadi Y, Houlden L, Albarenque SM, Zwacka RM.

Cell Death Differ. 2018 Feb;25(2):340-352. doi: 10.1038/cdd.2017.164. Epub 2017 Nov 3.


A monoclonal antibody raised against bacterially expressed MPV17 sequences shows peroxisomal, endosomal and lysosomal localisation in U2OS cells.

Weiher H, Pircher H, Jansen-Dürr P, Hegenbarth S, Knolle P, Grunau S, Vapola M, Hiltunen JK, Zwacka RM, Schmelzer E, Reumann K, Will H.

BMC Res Notes. 2016 Feb 27;9:128. doi: 10.1186/s13104-016-1939-0.


TRAIL-receptor preferences in pancreatic cancer cells revisited: Both TRAIL-R1 and TRAIL-R2 have a licence to kill.

Mohr A, Yu R, Zwacka RM.

BMC Cancer. 2015 Jul 3;15:494. doi: 10.1186/s12885-015-1508-2.


DR4 specific TRAIL variants are more efficacious than wild-type TRAIL in pancreatic cancer.

Yu R, Albarenque SM, Cool RH, Quax WJ, Mohr A, Zwacka RM.

Cancer Biol Ther. 2014;15(12):1658-66. doi: 10.4161/15384047.2014.972183.


TRAIL-induced apoptosis is preferentially mediated via TRAIL receptor 1 in pancreatic carcinoma cells and profoundly enhanced by XIAP inhibitors.

Stadel D, Mohr A, Ref C, MacFarlane M, Zhou S, Humphreys R, Bachem M, Cohen G, Möller P, Zwacka RM, Debatin KM, Fulda S.

Clin Cancer Res. 2010 Dec 1;16(23):5734-49. doi: 10.1158/1078-0432.CCR-10-0985. Epub 2010 Oct 12.


The enigmatic roles of caspases in tumor development.

Jäger R, Zwacka RM.

Cancers (Basel). 2010 Nov 24;2(4):1952-79. doi: 10.3390/cancers2041952.


Vitamin D3-24-hydroxylase (CYP24) as a potential target for intervention with diabetic and nondiabetic nephropathy.

Weiher H, Zwacka RM.

Clin Lab. 2007;53(1-2):85-8. No abstract available.


In situ trapping of initiator caspases reveals intermediate surprises.

Mohr A, Zwacka RM.

Cell Biol Int. 2007 May;31(5):526-30. Epub 2006 Nov 28.


Manganese superoxide dismutase induces p53-dependent senescence in colorectal cancer cells.

Behrend L, Mohr A, Dick T, Zwacka RM.

Mol Cell Biol. 2005 Sep;25(17):7758-69.

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