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Items: 1 to 20 of 266

1.

Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthood.

Stanelle-Bertram S, Walendy-Gnirß K, Speiseder T, Thiele S, Asante IA, Dreier C, Kouassi NM, Preuß A, Pilnitz-Stolze G, Müller U, Thanisch S, Richter M, Scharrenberg R, Kraus V, Dörk R, Schau L, Herder V, Gerhauser I, Pfankuche VM, Käufer C, Waltl I, Moraes T, Sellau J, Hoenow S, Schmidt-Chanasit J, Jansen S, Schattling B, Ittrich H, Bartsch U, Renné T, Bartenschlager R, Arck P, Cadar D, Friese MA, Vapalahti O, Lotter H, Benites S, Rolling L, Gabriel M, Baumgärtner W, Morellini F, Hölter SM, Amarie O, Fuchs H, Hrabe de Angelis M, Löscher W, Calderon de Anda F, Gabriel G.

Nat Microbiol. 2018 Sep 10. doi: 10.1038/s41564-018-0236-1. [Epub ahead of print]

PMID:
30202017
2.

An orthogonal proteomic survey uncovers novel Zika virus host factors.

Scaturro P, Stukalov A, Haas DA, Cortese M, Draganova K, Płaszczyca A, Bartenschlager R, Götz M, Pichlmair A.

Nature. 2018 Sep;561(7722):253-257. doi: 10.1038/s41586-018-0484-5. Epub 2018 Sep 3.

PMID:
30177828
3.

Novel non-heteroarylpyrimidine (HAP) capsid assembly modifiers have a different mode of action from HAPs in vitro.

Corcuera A, Stolle K, Hillmer S, Seitz S, Lee JY, Bartenschlager R, Birkmann A, Urban A.

Antiviral Res. 2018 Oct;158:135-142. doi: 10.1016/j.antiviral.2018.07.011. Epub 2018 Jul 20.

4.

A Reverse Genetics System for Zika Virus Based on a Simple Molecular Cloning Strategy.

Münster M, Płaszczyca A, Cortese M, Neufeldt CJ, Goellner S, Long G, Bartenschlager R.

Viruses. 2018 Jul 12;10(7). pii: E368. doi: 10.3390/v10070368.

5.

Semen inhibits Zika virus infection of cells and tissues from the anogenital region.

Müller JA, Harms M, Krüger F, Groß R, Joas S, Hayn M, Dietz AN, Lippold S, von Einem J, Schubert A, Michel M, Mayer B, Cortese M, Jang KS, Sandi-Monroy N, Deniz M, Ebner F, Vapalahti O, Otto M, Bartenschlager R, Herbeuval JP, Schmidt-Chanasit J, Roan NR, Münch J.

Nat Commun. 2018 Jun 7;9(1):2207. doi: 10.1038/s41467-018-04442-y.

6.

HCV modifies EGF signalling and upregulates production of CXCR2 ligands: Role in inflammation and antiviral immune response.

Groepper C, Rufinatscha K, Schröder N, Stindt S, Ehlting C, Albrecht U, Bock HH, Bartenschlager R, Häussinger D, Bode JG.

J Hepatol. 2018 Sep;69(3):594-602. doi: 10.1016/j.jhep.2018.04.005. Epub 2018 Apr 27.

PMID:
29705238
7.

Secretion of Hepatitis C Virus Replication Intermediates Reduces Activation of Toll-Like Receptor 3 in Hepatocytes.

Grünvogel O, Colasanti O, Lee JY, Klöss V, Belouzard S, Reustle A, Esser-Nobis K, Hesebeck-Brinckmann J, Mutz P, Hoffmann K, Mehrabi A, Koschny R, Vondran FWR, Gotthardt D, Schnitzler P, Neumann-Haefelin C, Thimme R, Binder M, Bartenschlager R, Dubuisson J, Dalpke AH, Lohmann V.

Gastroenterology. 2018 Jun;154(8):2237-2251.e16. doi: 10.1053/j.gastro.2018.03.020. Epub 2018 Mar 11.

8.

Hepatitis D virus replication is sensed by MDA5 and induces IFN-β/λ responses in hepatocytes.

Zhang Z, Filzmayer C, Ni Y, Sültmann H, Mutz P, Hiet MS, Vondran FWR, Bartenschlager R, Urban S.

J Hepatol. 2018 Jul;69(1):25-35. doi: 10.1016/j.jhep.2018.02.021. Epub 2018 Mar 8.

PMID:
29524530
9.

Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: Considerations for scientists and funding agencies.

Bartenschlager R, Baumert TF, Bukh J, Houghton M, Lemon SM, Lindenbach BD, Lohmann V, Moradpour D, Pietschmann T, Rice CM, Thimme R, Wakita T.

Virus Res. 2018 Mar 15;248:53-62. doi: 10.1016/j.virusres.2018.02.016. Epub 2018 Mar 2. Review.

10.

Structural Studies of Self-Assembled Subviral Particles: Combining Cell-Free Expression with 110 kHz MAS NMR Spectroscopy.

David G, Fogeron ML, Schledorn M, Montserret R, Haselmann U, Penzel S, Badillo A, Lecoq L, André P, Nassal M, Bartenschlager R, Meier BH, Böckmann A.

Angew Chem Int Ed Engl. 2018 Apr 16;57(17):4787-4791. doi: 10.1002/anie.201712091. Epub 2018 Mar 25.

PMID:
29457857
11.

Rewiring cellular networks by members of the Flaviviridae family.

Neufeldt CJ, Cortese M, Acosta EG, Bartenschlager R.

Nat Rev Microbiol. 2018 Feb 12;16(3):125-142. doi: 10.1038/nrmicro.2017.170. Review.

PMID:
29430005
12.

HBV Bypasses the Innate Immune Response and Does Not Protect HCV From Antiviral Activity of Interferon.

Mutz P, Metz P, Lempp FA, Bender S, Qu B, Schöneweis K, Seitz S, Tu T, Restuccia A, Frankish J, Dächert C, Schusser B, Koschny R, Polychronidis G, Schemmer P, Hoffmann K, Baumert TF, Binder M, Urban S, Bartenschlager R.

Gastroenterology. 2018 May;154(6):1791-1804.e22. doi: 10.1053/j.gastro.2018.01.044. Epub 2018 Feb 1.

13.

Glycine Zipper Motifs in Hepatitis C Virus Nonstructural Protein 4B Are Required for the Establishment of Viral Replication Organelles.

Paul D, Madan V, Ramirez O, Bencun M, Stoeck IK, Jirasko V, Bartenschlager R.

J Virol. 2018 Jan 30;92(4). pii: e01890-17. doi: 10.1128/JVI.01890-17. Print 2018 Feb 15.

14.

Hepatitis C virus-induced natural killer cell proliferation involves monocyte-derived cells and the OX40/OX40L axis.

Pollmann J, Götz JJ, Rupp D, Strauss O, Granzin M, Grünvogel O, Mutz P, Kramer C, Lasitschka F, Lohmann V, Björkström NK, Thimme R, Bartenschlager R, Cerwenka A.

J Hepatol. 2018 Mar;68(3):421-430. doi: 10.1016/j.jhep.2017.10.021. Epub 2017 Nov 1.

PMID:
29100993
15.

Membrane alterations induced by nonstructural proteins of human norovirus.

Doerflinger SY, Cortese M, Romero-Brey I, Menne Z, Tubiana T, Schenk C, White PA, Bartenschlager R, Bressanelli S, Hansman GS, Lohmann V.

PLoS Pathog. 2017 Oct 27;13(10):e1006705. doi: 10.1371/journal.ppat.1006705. eCollection 2017 Oct.

16.

Optimization of Substrate-Analogue Furin Inhibitors.

Ivanova T, Hardes K, Kallis S, Dahms SO, Than ME, Künzel S, Böttcher-Friebertshäuser E, Lindberg I, Jiao GS, Bartenschlager R, Steinmetzer T.

ChemMedChem. 2017 Dec 7;12(23):1953-1968. doi: 10.1002/cmdc.201700596. Epub 2017 Nov 16.

PMID:
29059503
17.

Hepatitis C Virus Replication Depends on Endosomal Cholesterol Homeostasis.

Stoeck IK, Lee JY, Tabata K, Romero-Brey I, Paul D, Schult P, Lohmann V, Kaderali L, Bartenschlager R.

J Virol. 2017 Dec 14;92(1). pii: e01196-17. doi: 10.1128/JVI.01196-17. Print 2018 Jan 1.

18.

Host-directed therapies for bacterial and viral infections.

Kaufmann SHE, Dorhoi A, Hotchkiss RS, Bartenschlager R.

Nat Rev Drug Discov. 2018 Jan;17(1):35-56. doi: 10.1038/nrd.2017.162. Epub 2017 Sep 22. Review.

PMID:
28935918
19.

Deciphering the Origin and Evolution of Hepatitis B Viruses by Means of a Family of Non-enveloped Fish Viruses.

Lauber C, Seitz S, Mattei S, Suh A, Beck J, Herstein J, Börold J, Salzburger W, Kaderali L, Briggs JAG, Bartenschlager R.

Cell Host Microbe. 2017 Sep 13;22(3):387-399.e6. doi: 10.1016/j.chom.2017.07.019. Epub 2017 Aug 31.

20.

Genome packaging of reovirus is mediated by the scaffolding property of the microtubule network.

Shah PNM, Stanifer ML, Höhn K, Engel U, Haselmann U, Bartenschlager R, Kräusslich HG, Krijnse-Locker J, Boulant S.

Cell Microbiol. 2017 Dec;19(12). doi: 10.1111/cmi.12765. Epub 2017 Jul 21.

PMID:
28672089

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