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Items: 1 to 20 of 25

1.

Iron as Therapeutic Target in Human Diseases.

Gozzelino R, Poli M, Arosio P.

Pharmaceuticals (Basel). 2019 Dec 5;12(4). pii: E178. doi: 10.3390/ph12040178.

2.

Multilevel Impacts of Iron in the Brain: The Cross Talk between Neurophysiological Mechanisms, Cognition, and Social Behavior.

Ferreira A, Neves P, Gozzelino R.

Pharmaceuticals (Basel). 2019 Aug 29;12(3). pii: E126. doi: 10.3390/ph12030126. Review.

3.

Renal control of disease tolerance to malaria.

Ramos S, Carlos AR, Sundaram B, Jeney V, Ribeiro A, Gozzelino R, Bank C, Gjini E, Braza F, Martins R, Ademolue TW, Blankenhaus B, Gouveia Z, Faísca P, Trujillo D, Cardoso S, Rebelo S, Del Barrio L, Zarjou A, Bolisetty S, Agarwal A, Soares MP.

Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5681-5686. doi: 10.1073/pnas.1822024116. Epub 2019 Mar 4.

4.

An Iron-Rich Diet Decreases the Mycobacterial Burden and Correlates With Hepcidin Upregulation, Lower Levels of Proinflammatory Mediators, and Increased T-Cell Recruitment in a Model of Mycobacterium bovis Bacille Calmette-Guerin Infection.

Agoro R, Benmerzoug S, Rose S, Bouyer M, Gozzelino R, Garcia I, Ryffel B, Quesniaux VFJ, Mura C.

J Infect Dis. 2017 Oct 17;216(7):907-918. doi: 10.1093/infdis/jix366.

PMID:
28973651
5.

Iron Metabolism and the Inflammatory Response.

Martins AC, Almeida JI, Lima IS, Kapitão AS, Gozzelino R.

IUBMB Life. 2017 Jun;69(6):442-450. doi: 10.1002/iub.1635. Epub 2017 May 5. Review.

6.

Iron Homeostasis in Health and Disease.

Gozzelino R, Arosio P.

Int J Mol Sci. 2016 Jan 20;17(1). pii: E130. doi: 10.3390/ijms17010130. Review.

7.

The importance of eukaryotic ferritins in iron handling and cytoprotection.

Arosio P, Carmona F, Gozzelino R, Maccarinelli F, Poli M.

Biochem J. 2015 Nov 15;472(1):1-15. doi: 10.1042/BJ20150787. Review.

PMID:
26518749
8.

The Pathophysiology of Heme in the Brain.

Gozzelino R.

Curr Alzheimer Res. 2016;13(2):174-84. Review.

PMID:
26391040
9.

The importance of iron in pathophysiologic conditions.

Gozzelino R, Arosio P.

Front Pharmacol. 2015 Feb 24;6:26. doi: 10.3389/fphar.2015.00026. eCollection 2015. No abstract available.

10.

Gut microbiota elicits a protective immune response against malaria transmission.

Yilmaz B, Portugal S, Tran TM, Gozzelino R, Ramos S, Gomes J, Regalado A, Cowan PJ, d'Apice AJ, Chong AS, Doumbo OK, Traore B, Crompton PD, Silveira H, Soares MP.

Cell. 2014 Dec 4;159(6):1277-89. doi: 10.1016/j.cell.2014.10.053.

11.

Tissue damage control in disease tolerance.

Soares MP, Gozzelino R, Weis S.

Trends Immunol. 2014 Oct;35(10):483-94. doi: 10.1016/j.it.2014.08.001. Epub 2014 Aug 30. Review.

PMID:
25182198
12.

Iron overload in Plasmodium berghei-infected placenta as a pathogenesis mechanism of fetal death.

Penha-Gonçalves C, Gozzelino R, de Moraes LV.

Front Pharmacol. 2014 Jul 1;5:155. doi: 10.3389/fphar.2014.00155. eCollection 2014.

13.

Anthracyclines induce DNA damage response-mediated protection against severe sepsis.

Figueiredo N, Chora A, Raquel H, Pejanovic N, Pereira P, Hartleben B, Neves-Costa A, Moita C, Pedroso D, Pinto A, Marques S, Faridi H, Costa P, Gozzelino R, Zhao JL, Soares MP, Gama-Carvalho M, Martinez J, Zhang Q, Döring G, Grompe M, Simas JP, Huber TB, Baltimore D, Gupta V, Green DR, Ferreira JA, Moita LF.

Immunity. 2013 Nov 14;39(5):874-84. doi: 10.1016/j.immuni.2013.08.039. Epub 2013 Oct 31.

14.

Coupling heme and iron metabolism via ferritin H chain.

Gozzelino R, Soares MP.

Antioxid Redox Signal. 2014 Apr 10;20(11):1754-69. doi: 10.1089/ars.2013.5666. Epub 2013 Dec 10. Review.

15.

NF-κB activation fails to protect cells to TNFα-induced apoptosis in the absence of Bcl-xL, but not Mcl-1, Bcl-2 or Bcl-w.

Casanelles E, Gozzelino R, Marqués-Fernández F, Iglesias-Guimarais V, Garcia-Belinchón M, Sánchez-Osuna M, Solé C, Moubarak RS, Comella JX, Yuste VJ.

Biochim Biophys Acta. 2013 May;1833(5):1085-95. doi: 10.1016/j.bbamcr.2013.01.014. Epub 2013 Jan 28.

16.

Metabolic adaptation to tissue iron overload confers tolerance to malaria.

Gozzelino R, Andrade BB, Larsen R, Luz NF, Vanoaica L, Seixas E, Coutinho A, Cardoso S, Rebelo S, Poli M, Barral-Netto M, Darshan D, Kühn LC, Soares MP.

Cell Host Microbe. 2012 Nov 15;12(5):693-704. doi: 10.1016/j.chom.2012.10.011.

17.

Heme cytotoxicity and the pathogenesis of immune-mediated inflammatory diseases.

Larsen R, Gouveia Z, Soares MP, Gozzelino R.

Front Pharmacol. 2012 May 4;3:77. doi: 10.3389/fphar.2012.00077. eCollection 2012.

18.

Heme sensitization to TNF-mediated programmed cell death.

Gozzelino R, Soares MP.

Adv Exp Med Biol. 2011;691:211-9. doi: 10.1007/978-1-4419-6612-4_22. No abstract available.

PMID:
21153325
19.

A central role for free heme in the pathogenesis of severe sepsis.

Larsen R, Gozzelino R, Jeney V, Tokaji L, Bozza FA, Japiassú AM, Bonaparte D, Cavalcante MM, Chora A, Ferreira A, Marguti I, Cardoso S, Sepúlveda N, Smith A, Soares MP.

Sci Transl Med. 2010 Sep 29;2(51):51ra71. doi: 10.1126/scitranslmed.3001118.

20.

The death receptor antagonist FLIP-L interacts with Trk and is necessary for neurite outgrowth induced by neurotrophins.

Moubarak RS, Solé C, Pascual M, Gutierrez H, Llovera M, Pérez-García MJ, Gozzelino R, Segura MF, Iglesias-Guimarais V, Reix S, Soler RM, Davies AM, Soriano E, Yuste VJ, Comella JX.

J Neurosci. 2010 Apr 28;30(17):6094-105. doi: 10.1523/JNEUROSCI.0537-10.2010.

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