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Items: 8


The use of Sulfonamide Derivatives in the Treatment of Trypanosomatid Parasites, Including Trypanosoma cruzi, Trypanosoma brucei, and Leishmania ssp.

Scarim CB, Chelucci RC, Dos Santos JL, Chin CM.

Med Chem. 2019 Jun 20. doi: 10.2174/1573406415666190620141109. [Epub ahead of print]


Current advances in drug discovery for Chagas disease.

Scarim CB, Jornada DH, Chelucci RC, de Almeida L, Dos Santos JL, Chung MC.

Eur J Med Chem. 2018 Jul 15;155:824-838. doi: 10.1016/j.ejmech.2018.06.040. Epub 2018 Jun 20. Review.


Discovery of phenylsulfonylfuroxan derivatives as gamma globin inducers by histone acetylation.

Melo TRF, Kumkhaek C, Fernandes GFDS, Lopes Pires ME, Chelucci RC, Barbieri KP, Coelho F, Capote TSO, Lanaro C, Carlos IZ, Marcondes S, Chegaev K, Guglielmo S, Fruttero R, Chung MC, Costa FF, Rodgers GP, Dos Santos JL.

Eur J Med Chem. 2018 Jun 25;154:341-353. doi: 10.1016/j.ejmech.2018.05.008. Epub 2018 May 30.


Synthesis and evaluation of novel dapsone-thalidomide hybrids for the treatment of type 2 leprosy reactions.

Yamasaki PR, do Nascimento DC, Chelucci RC, de Faria Fernandes Belone A, Rosa PS, Diório SM, de Melo TR, Barbieri KP, Placeres MC, Carlos IZ, Chung MC, dos Santos JL.

Bioorg Med Chem Lett. 2014 Jul 15;24(14):3084-7. doi: 10.1016/j.bmcl.2014.05.017. Epub 2014 May 16.


Pharmacological evaluation and preparation of nonsteroidal anti-inflammatory drugs containing an N-acyl hydrazone subunit.

de Melo TR, Chelucci RC, Pires ME, Dutra LA, Barbieri KP, Bosquesi PL, Trossini GH, Chung MC, dos Santos JL.

Int J Mol Sci. 2014 Apr 4;15(4):5821-37. doi: 10.3390/ijms15045821.


Antiplatelet and antithrombotic activities of non-steroidal anti-inflammatory drugs containing an N-acyl hydrazone subunit.

Chelucci RC, Dutra LA, Lopes Pires ME, de Melo TR, Bosquesi PL, Chung MC, Dos Santos JL.

Molecules. 2014 Feb 17;19(2):2089-99. doi: 10.3390/molecules19022089.


Pharmacological evaluation and preliminary pharmacokinetics studies of a new diclofenac prodrug without gastric ulceration effect.

Santos JL, Moreira V, Campos ML, Chelucci RC, Barbieri KP, de Castro Souto PC, Matsubara MH, Teixeira C, Bosquesi PL, Peccinini RG, Chin CM.

Int J Mol Sci. 2012 Nov 19;13(11):15305-20. doi: 10.3390/ijms131115305.


Design, synthesis, and pharmacological evaluation of novel hybrid compounds to treat sickle cell disease symptoms. part II: furoxan derivatives.

Dos Santos JL, Lanaro C, Chelucci RC, Gambero S, Bosquesi PL, Reis JS, Lima LM, Cerecetto H, González M, Costa FF, Chung MC.

J Med Chem. 2012 Sep 13;55(17):7583-92. doi: 10.1021/jm300602n. Epub 2012 Aug 21.


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