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Items: 1 to 20 of 33

1.

ABC Transporters and Their Role in the Neoadjuvant Treatment of Esophageal Cancer.

Vrana D, Hlavac V, Brynychova V, Vaclavikova R, Neoral C, Vrba J, Aujesky R, Matzenauer M, Melichar B, Soucek P.

Int J Mol Sci. 2018 Mar 15;19(3). pii: E868. doi: 10.3390/ijms19030868. Review.

2.

Gene Expression Profiling Reveals Novel Candidate Markers of Ovarian Carcinoma Intraperitoneal Metastasis.

Elsnerova K, Bartakova A, Tihlarik J, Bouda J, Rob L, Skapa P, Hruda M, Gut I, Mohelnikova-Duchonova B, Soucek P, Vaclavikova R.

J Cancer. 2017 Oct 9;8(17):3598-3606. doi: 10.7150/jca.20766. eCollection 2017.

3.

The role of membrane transporters in ovarian cancer chemoresistance and prognosis.

Cerovska E, Elsnerova K, Vaclavikova R, Soucek P.

Expert Opin Drug Metab Toxicol. 2017 Jul;13(7):741-753. doi: 10.1080/17425255.2017.1332179. Epub 2017 May 29. Review.

PMID:
28511565
4.

Expression of oxysterol pathway genes in oestrogen-positive breast carcinomas.

Kloudova A, Brynychova V, Vaclavikova R, Vrana D, Gatek J, Mrhalova M, Kodet R, Soucek P.

Clin Endocrinol (Oxf). 2017 Jun;86(6):852-861. doi: 10.1111/cen.13337. Epub 2017 Apr 24.

PMID:
28342201
5.

Genetic and functional analyses do not explain the association of high PRC1 expression with poor survival of breast carcinoma patients.

Brynychova V, Ehrlichova M, Hlavac V, Nemcova-Furstova V, Pecha V, Leva J, Trnkova M, Mrhalova M, Kodet R, Vrana D, Kovar J, Vaclavikova R, Gut I, Soucek P.

Biomed Pharmacother. 2016 Oct;83:857-864. doi: 10.1016/j.biopha.2016.07.047. Epub 2016 Aug 6.

PMID:
27505863
6.

Characterization of acquired paclitaxel resistance of breast cancer cells and involvement of ABC transporters.

Němcová-Fürstová V, Kopperová D, Balušíková K, Ehrlichová M, Brynychová V, Václavíková R, Daniel P, Souček P, Kovář J.

Toxicol Appl Pharmacol. 2016 Nov 1;310:215-228. doi: 10.1016/j.taap.2016.09.020. Epub 2016 Sep 21.

PMID:
27664577
7.

Transcript expression and genetic variability analysis of caspases in breast carcinomas suggests CASP9 as the most interesting target.

Brynychova V, Hlavac V, Ehrlichova M, Vaclavikova R, Nemcova-Furstova V, Pecha V, Trnkova M, Mrhalova M, Kodet R, Vrana D, Gatek J, Bendova M, Vernerova Z, Kovar J, Soucek P.

Clin Chem Lab Med. 2017 Jan 1;55(1):111-122. doi: 10.1515/cclm-2016-0271.

PMID:
27327132
8.

Gene expression of membrane transporters: Importance for prognosis and progression of ovarian carcinoma.

Elsnerova K, Mohelnikova-Duchonova B, Cerovska E, Ehrlichova M, Gut I, Rob L, Skapa P, Hruda M, Bartakova A, Bouda J, Vodicka P, Soucek P, Vaclavikova R.

Oncol Rep. 2016 Apr;35(4):2159-70. doi: 10.3892/or.2016.4599. Epub 2016 Jan 28.

PMID:
26820484
9.

Microsomal epoxide hydrolase 1 (EPHX1): Gene, structure, function, and role in human disease.

Václavíková R, Hughes DJ, Souček P.

Gene. 2015 Oct 15;571(1):1-8. doi: 10.1016/j.gene.2015.07.071. Epub 2015 Jul 26. Review.

10.

The role of cytochromes p450 and aldo-keto reductases in prognosis of breast carcinoma patients.

Hlaváč V, Brynychová V, Václavíková R, Ehrlichová M, Vrána D, Pecha V, Trnková M, Kodet R, Mrhalová M, Kubáčková K, Gatěk J, Vážan P, Souček P.

Medicine (Baltimore). 2014 Dec;93(28):e255. doi: 10.1097/MD.0000000000000255.

11.

Can the assessment of ABCB1 gene expression predict its function in vitro?

Kosztyu P, Dolezel P, Vaclavikova R, Mlejnek P.

Eur J Haematol. 2015 Aug;95(2):150-9. doi: 10.1111/ejh.12470. Epub 2015 Jan 22.

PMID:
25323158
12.

Non-coding polymorphisms in nucleotide binding domain 1 in ABCC1 gene associate with transcript level and survival of patients with breast cancer.

Kunická T, Václavíková R, Hlaváč V, Vrána D, Pecha V, Rauš K, Trnková M, Kubáčková K, Ambruš M, Vodičková L, Vodička P, Souček P.

PLoS One. 2014 Jul 31;9(7):e101740. doi: 10.1371/journal.pone.0101740. eCollection 2014.

13.

The expression profile of ATP-binding cassette transporter genes in breast carcinoma.

Hlaváč V, Brynychová V, Václavíková R, Ehrlichová M, Vrána D, Pecha V, Koževnikovová R, Trnková M, Gatěk J, Kopperová D, Gut I, Souček P.

Pharmacogenomics. 2013 Apr;14(5):515-29. doi: 10.2217/pgs.13.26.

PMID:
23556449
14.

The association of taxane resistance genes with the clinical course of ovarian carcinoma.

Ehrlichova M, Mohelnikova-Duchonova B, Hrdy J, Brynychova V, Mrhalova M, Kodet R, Rob L, Pluta M, Gut I, Soucek P, Vaclavikova R.

Genomics. 2013 Aug;102(2):96-101. doi: 10.1016/j.ygeno.2013.03.005. Epub 2013 Mar 28.

15.

Importance of transcript levels of caspase-2 isoforms S and L for breast carcinoma progression.

Brynychová V, Hlaváč V, Ehrlichová M, Václavíková R, Pecha V, Trnková M, Wald M, Mrhalová M, Kubáčková K, Pikus T, Kodet R, Kovář J, Souček P.

Future Oncol. 2013 Mar;9(3):427-38. doi: 10.2217/fon.12.200.

PMID:
23469978
16.

Detection of frequent ABCB1 polymorphisms by high-resolution melting curve analysis and their effect on breast carcinoma prognosis.

Vaclavikova R, Ehrlichova M, Hlavata I, Pecha V, Kozevnikovova R, Trnkova M, Adamek J, Edvardsen H, Kristensen VN, Gut I, Soucek P.

Clin Chem Lab Med. 2012 Nov;50(11):1999-2007. doi: 10.1515/cclm-2012-0103.

PMID:
23093106
17.

Transport, metabolism, cytotoxicity and effects of novel taxanes on the cell cycle in MDA-MB-435 and NCI/ADR-RES cells.

Ehrlichová M, Ojima I, Chen J, Václavíková R, Němcová-Fürstová V, Vobořilová J, Simek P, Horský S, Souček P, Kovář J, Brabec M, Gut I.

Naunyn Schmiedebergs Arch Pharmacol. 2012 Oct;385(10):1035-48. doi: 10.1007/s00210-012-0785-4. Epub 2012 Aug 2.

PMID:
22855252
18.

Beta-3 agonist-induced lipolysis and nitric oxide production: relationship to PPARgamma agonist/antagonist and AMP kinase modulation.

Hodis J, Vaclavíková R, Farghali H.

Gen Physiol Biophys. 2011 Mar;30(1):90-9. doi: 10.4149/gpb_2011_01_90.

PMID:
21460417
19.

Second-generation taxanes effectively suppress subcutaneous rat lymphoma: role of disposition, transport, metabolism, in vitro potency and expression of angiogenesis genes.

Otová B, Ojima I, Václavíková R, Hrdý J, Ehrlichová M, Souček P, Vobořilová J, Němcová V, Zanardi I, Horský S, Kovář J, Gut I.

Invest New Drugs. 2012 Jun;30(3):991-1002. doi: 10.1007/s10637-011-9654-0. Epub 2011 Mar 30.

PMID:
21448670
20.

Association of superoxide dismutases and NAD(P)H quinone oxidoreductases with prognosis of patients with breast carcinomas.

Hubackova M, Vaclavikova R, Ehrlichova M, Mrhalova M, Kodet R, Kubackova K, Vrána D, Gut I, Soucek P.

Int J Cancer. 2012 Jan 15;130(2):338-48. doi: 10.1002/ijc.26006. Epub 2011 Apr 20.

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