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Items: 20

1.

Enzymatic Preparation of 2'-5',3'-5'-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations.

Novotná B, Vaneková L, Zavřel M, Buděšínský M, Dejmek M, Smola M, Gutten O, Tehrani ZA, Pimková Polidarová M, Brázdová A, Liboska R, Štěpánek I, Vavřina Z, Jandušík T, Nencka R, Rulíšek L, Bouřa E, Brynda J, Páv O, Birkuš G.

J Med Chem. 2019 Dec 12;62(23):10676-10690. doi: 10.1021/acs.jmedchem.9b01062. Epub 2019 Nov 27.

PMID:
31715099
2.

Solid-Phase Synthesis of Phosphorothioate/Phosphonothioate and Phosphoramidate/Phosphonamidate Oligonucleotides.

Kostov O, Liboska R, Páv O, Novák P, Rosenberg I.

Molecules. 2019 May 15;24(10). pii: E1872. doi: 10.3390/molecules24101872.

3.

Tuning the hybridization properties of modified oligonucleotides: from flexible to conformationally constrained phosphonate internucleotide linkages.

Páv O, Barvík I, Liboska R, Petrová M, Šimák O, Rosenbergová Š, Novák P, Buděšínský M, Rosenberg I.

Org Biomol Chem. 2017 Jan 18;15(3):701-707. doi: 10.1039/c6ob02571d.

PMID:
27995239
4.

4-Toluenesulfonyloxymethyl-(H)-phosphinate: A Reagent for the Introduction of O- and S-Methyl-(H)-phosphinate Moieties.

Kostov O, Páv O, Buděšínský M, Liboska R, Šimák O, Petrová M, Novák P, Rosenberg I.

Org Lett. 2016 Jun 3;18(11):2704-7. doi: 10.1021/acs.orglett.6b01167. Epub 2016 May 13.

PMID:
27177076
5.

Dr Jekyll and Mr Hyde: a strange case of 5-ethynyl-2'-deoxyuridine and 5-ethynyl-2'-deoxycytidine.

Ligasová A, Liboska R, Friedecký D, Mičová K, Adam T, Oždian T, Rosenberg I, Koberna K.

Open Biol. 2016 Jan;6(1):150172. doi: 10.1098/rsob.150172.

6.

The Fingerprint of Anti-Bromodeoxyuridine Antibodies and Its Use for the Assessment of Their Affinity to 5-Bromo-2'-Deoxyuridine in Cellular DNA under Various Conditions.

Ligasová A, Liboska R, Rosenberg I, Koberna K.

PLoS One. 2015 Jul 10;10(7):e0132393. doi: 10.1371/journal.pone.0132393. eCollection 2015.

7.

Straightforward Synthesis of Purine 4'-Alkoxy-2'-deoxynucleosides: First Report of Mixed Purine-Pyrimidine 4'-Alkoxyoligodeoxynucleotides as New RNA Mimics.

Petrová M, Páv O, Buděšínský M, Zborníková E, Novák P, Rosenbergová Š, Pačes O, Liboska R, Dvořáková I, Šimák O, Rosenberg I.

Org Lett. 2015 Jul 17;17(14):3426-9. doi: 10.1021/acs.orglett.5b01430. Epub 2015 Jul 2.

PMID:
26133076
8.

5'-O-Methylphosphonate nucleic acids--new modified DNAs that increase the Escherichia coli RNase H cleavage rate of hybrid duplexes.

Šipova H, Špringer T, Rejman D, Šimak O, Petrová M, Novák P, Rosenbergová Š, Páv O, Liboska R, Barvík I, Štěpanek J, Rosenberg I, Homola J.

Nucleic Acids Res. 2014 Apr;42(8):5378-89. doi: 10.1093/nar/gku125. Epub 2014 Feb 12.

9.

Inhibition of human thymidine phosphorylase by conformationally constrained pyrimidine nucleoside phosphonic acids and their "open-structure" isosteres.

Košiová I, Šimák O, Panova N, Buděšínský M, Petrová M, Rejman D, Liboska R, Páv O, Rosenberg I.

Eur J Med Chem. 2014 Mar 3;74:145-68. doi: 10.1016/j.ejmech.2013.12.026. Epub 2014 Jan 3.

PMID:
24462848
10.

Atomic scissors: a new method of tracking the 5-bromo-2'-deoxyuridine-labeled DNA in situ.

Ligasová A, Strunin D, Liboska R, Rosenberg I, Koberna K.

PLoS One. 2012;7(12):e52584. doi: 10.1371/journal.pone.0052584. Epub 2012 Dec 26.

11.

Most anti-BrdU antibodies react with 2'-deoxy-5-ethynyluridine -- the method for the effective suppression of this cross-reactivity.

Liboska R, Ligasová A, Strunin D, Rosenberg I, Koberna K.

PLoS One. 2012;7(12):e51679. doi: 10.1371/journal.pone.0051679. Epub 2012 Dec 18.

12.

4'-Alkoxy oligodeoxynucleotides: a novel class of RNA mimics.

Liboska R, Snášel J, Barvík I, Buděšínský M, Pohl R, Točík Z, Páv O, Rejman D, Novák P, Rosenberg I.

Org Biomol Chem. 2011 Dec 21;9(24):8261-7. doi: 10.1039/c1ob06148h. Epub 2011 Nov 3.

PMID:
22051918
13.

Unusual activity pattern of leucine aminopeptidase inhibitors based on phosphorus containing derivatives of methionine and norleucine.

Pícha J, Liboska R, Buděšínský M, Jiráček J, Pawełczak M, Mucha A.

J Enzyme Inhib Med Chem. 2011 Apr;26(2):155-61. doi: 10.3109/14756366.2010.482047. Epub 2010 Jun 28.

PMID:
20578976
14.

Structural diversity of nucleoside phosphonic acids as a key factor in the discovery of potent inhibitors of rat T-cell lymphoma thymidine phosphorylase.

Kocalka P, Rejman D, Vanek V, Rinnová M, Tomecková I, Králíková S, Petrová M, Páv O, Pohl R, Budesínský M, Liboska R, Tocík Z, Panova N, Votruba I, Rosenberg I.

Bioorg Med Chem Lett. 2010 Feb 1;20(3):862-5. doi: 10.1016/j.bmcl.2009.12.081. Epub 2009 Dec 28.

PMID:
20053558
15.

Nucleoside phosphonic acids in thymidine phosphorylase inhibition: structure-activity relationship.

Panova N, Kosiová I, Petrová M, Vanĕk V, Liboska R, Kovacková S, Kocalka P, Králíková S, Tocík Z, Páv O, Paces O, Rejman D, Rosenberg I.

Nucleic Acids Symp Ser (Oxf). 2008;(52):665-6. doi: 10.1093/nass/nrn336.

PMID:
18776555
16.

Prolinol-based nucleoside phosphonic acids: synthesis and properties.

Vanĕk V, Budĕsínský M, Liboska R, Hurychová V, Rosenberg I.

Nucleic Acids Symp Ser (Oxf). 2008;(52):537-8. doi: 10.1093/nass/nrn272.

PMID:
18776491
17.

Chiral phosphonate internucleotide linkage: a promising modification for chimeric oligonucleotides?

Liboska R, Petrová M, Pohl R, Budesínsky M, Hurychová V, Rosenberg I.

Nucleic Acids Symp Ser (Oxf). 2008;(52):317-8. doi: 10.1093/nass/nrn160.

PMID:
18776381
18.

Investigating oligonucleotide hybridization at subnanomolar level by surface plasmon resonance biosensor method.

Vaisocherová H, Zítová A, Lachmanová M, Stepánek J, Králíková S, Liboska R, Rejman D, Rosenberg I, Homola J.

Biopolymers. 2006 Jul;82(4):394-8.

PMID:
16365848
19.

Hybridization properties of 4'-branched oligonucleotides.

Liboska R, Budesínský M, Dvoráková-Kavenová I, Páv O, Rosenberg I.

Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1057-60. No abstract available.

PMID:
14565343
20.

Oligomerization aiming at phosphonate analogues of oligoadenylates.

Pressová M, Liboska R, Budesínský M, Králíková S, Kavenová I, Rosenberg I.

Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1049-52.

PMID:
14565341

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