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Items: 1 to 20 of 99

1.

New Zampanolide Mimics: Design, Synthesis, and Antiproliferative Evaluation.

Chen G, Jiang Z, Zhang Q, Wang G, Chen QH.

Molecules. 2020 Jan 15;25(2). pii: E362. doi: 10.3390/molecules25020362.

2.

PP2Cδ inhibits p300-mediated p53 acetylation via ATM/BRCA1 pathway to impede DNA damage response in breast cancer.

Li Q, Hao Q, Cao W, Li J, Wu K, Elshimali Y, Zhu D, Chen QH, Chen G, Pollack JR, Vadgama J, Wu Y.

Sci Adv. 2019 Oct 16;5(10):eaaw8417. doi: 10.1126/sciadv.aaw8417. eCollection 2019 Oct.

3.

A novel curcumin analog inhibits canonical and non-canonical functions of telomerase through STAT3 and NF-κB inactivation in colorectal cancer cells.

Chung SS, Dutta P, Chard N, Wu Y, Chen QH, Chen G, Vadgama J.

Oncotarget. 2019 Jul 16;10(44):4516-4531. doi: 10.18632/oncotarget.27000. eCollection 2019 Jul 16.

4.

Mosquito Acetylcholinesterase as a Target for Novel Phenyl-Substituted Carbamates.

Mutunga JM, Ma M, Chen QH, Hartsel JA, Wong DM, Ding S, Totrov M, Carlier PR, Bloomquist JR.

Int J Environ Res Public Health. 2019 Apr 28;16(9). pii: E1500. doi: 10.3390/ijerph16091500.

5.

Synthesis and antiproliferative evaluation of new zampanolide mimics.

Chen G, Patanapongpibul M, Jiang Z, Zhang Q, Zheng S, Wang G, White JD, Chen QH.

Org Biomol Chem. 2019 Apr 10;17(15):3830-3844. doi: 10.1039/c9ob00556k.

PMID:
30924817
6.

Nitrogen-containing derivatives of O-tetramethylquercetin: Synthesis and biological profiles in prostate cancer cell models.

Rajaram P, Jiang Z, Chen G, Rivera A, Phasakda A, Zhang Q, Zheng S, Wang G, Chen QH.

Bioorg Chem. 2019 Jun;87:227-239. doi: 10.1016/j.bioorg.2019.03.047. Epub 2019 Mar 19.

PMID:
30904813
7.

Select β- and γ-branched 1-alkylpyrazol-4-yl methylcarbamates exhibit high selectivity for inhibition of Anopheles gambiae versus human acetylcholinesterase.

Carlier PR, Chen QH, Verma A, Wong DM, Mutunga JM, Müller J, Islam R, Shimozono AM, Tong F, Li J, Totrov M, Bloomquist JR.

Pestic Biochem Physiol. 2018 Oct;151:32-39. doi: 10.1016/j.pestbp.2018.02.003. Epub 2018 Feb 13.

8.

O-Aminoalkyl-O-Trimethyl-2,3-Dehydrosilybins: Synthesis and In Vitro Effects Towards Prostate Cancer Cells.

Vue B, Zhang S, Vignau A, Chen G, Zhang X, Diaz W, Zhang Q, Zheng S, Wang G, Chen QH.

Molecules. 2018 Nov 29;23(12). pii: E3142. doi: 10.3390/molecules23123142.

9.

Structure-activity relationship and pharmacokinetic studies of 3-O-substitutedflavonols as anti-prostate cancer agents.

Li X, Zhang C, Guo S, Rajaram P, Lee M, Chen G, Fong R, Gonzalez A, Zhang Q, Zheng S, Wang G, Chen QH.

Eur J Med Chem. 2018 Sep 5;157:978-993. doi: 10.1016/j.ejmech.2018.08.047. Epub 2018 Aug 22.

10.

Optimization of diarylpentadienones as chemotherapeutics for prostate cancer.

Patanapongpibul M, Zhang C, Chen G, Guo S, Zhang Q, Zheng S, Wang G, Chen QH.

Bioorg Med Chem. 2018 Sep 1;26(16):4751-4760. doi: 10.1016/j.bmc.2018.08.018. Epub 2018 Aug 13.

11.

Targeting of PP2Cδ By a Small Molecule C23 Inhibits High Glucose-Induced Breast Cancer Progression In Vivo.

Wu K, Yu X, Huang Z, Zhu D, Yi X, Wu YL, Hao Q, Kemp KT 2nd, Elshimali Y, Iyer R, Nguyen KT, Zheng S, Chen G, Chen QH, Wang G, Vadgama JV, Wu Y.

Antioxid Redox Signal. 2019 Jun 10;30(17):1983-1998. doi: 10.1089/ars.2017.7486. Epub 2018 Jul 13.

PMID:
29808718
12.

Optimized synthesis and antiproliferative activity of desTHPdactylolides.

Chen G, Wang R, Vue B, Patanapongpibul M, Zhang Q, Zheng S, Wang G, White JD, Chen QH.

Bioorg Med Chem. 2018 Jul 23;26(12):3514-3520. doi: 10.1016/j.bmc.2018.05.026. Epub 2018 May 18.

13.

3-O-Substituted-3',4',5'-trimethoxyflavonols: Synthesis and cell-based evaluation as anti-prostate cancer agents.

Li X, Lee M, Chen G, Zhang Q, Zheng S, Wang G, Chen QH.

Bioorg Med Chem. 2017 Sep 1;25(17):4768-4777. doi: 10.1016/j.bmc.2017.07.022. Epub 2017 Jul 21.

14.

5- or/and 20-O-alkyl-2,3-dehydrosilybins: Synthesis and biological profiles on prostate cancer cell models.

Vue B, Zhang X, Lee T, Nair N, Zhang S, Chen G, Zhang Q, Zheng S, Wang G, Chen QH.

Bioorg Med Chem. 2017 Sep 1;25(17):4845-4854. doi: 10.1016/j.bmc.2017.07.035. Epub 2017 Jul 20.

15.

Immune Modulation of Asian Folk Herbal Medicines and Related Chemical Components for Cancer Management.

Patanapongpibul M, Chen QH.

Curr Med Chem. 2019;26(17):3042-3067. doi: 10.2174/0929867324666170705112644. Review.

PMID:
28685684
16.

Asymmetric 1,5-diarylpenta-1,4-dien-3-ones: Antiproliferative activity in prostate epithelial cell models and pharmacokinetic studies.

Zhang X, Guo S, Chen C, Perez GR, Zhang C, Patanapongpibul M, Subrahmanyam N, Wang R, Keith J, Chen G, Dong Y, Zhang Q, Zhong Q, Zheng S, Wang G, Chen QH.

Eur J Med Chem. 2017 Sep 8;137:263-279. doi: 10.1016/j.ejmech.2017.05.062. Epub 2017 Jun 3.

17.

Structure-activity relationship studies of 1,7-diheteroarylhepta-1,4,6-trien-3-ones with two different terminal rings in prostate epithelial cell models.

Wang R, Zhang X, Chen C, Chen G, Sarabia C, Zhang Q, Zheng S, Wang G, Chen QH.

Eur J Med Chem. 2017 Jun 16;133:208-226. doi: 10.1016/j.ejmech.2017.03.067. Epub 2017 Mar 29.

18.

Bivalent Carbamates as Novel Control Agents of the Malaria Mosquito, Anopheles gambiae.

Mutunga JM, Chen QH, Wong DM, Lam PC, Li J, Totrov MM, Gross AD, Carlier PR, Bloomquist JR.

Chimia (Aarau). 2016 Oct;70(10):704-708.

PMID:
27779928
19.

The Potential of Flavonolignans in Prostate Cancer Management.

Vue B, Chen QH.

Curr Med Chem. 2016;23(34):3925-3950. Review.

PMID:
27557939
20.

Design, synthesis, and biological evaluation of 1,9-diheteroarylnona-1,3,6,8-tetraen-5-ones as a new class of anti-prostate cancer agents.

Zhang X, Wang R, Perez GR, Chen G, Zhang Q, Zheng S, Wang G, Chen QH.

Bioorg Med Chem. 2016 Oct 1;24(19):4692-4700. doi: 10.1016/j.bmc.2016.08.006. Epub 2016 Aug 6.

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