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Items: 1 to 20 of 174


BCL-6 suppresses miR-142-3p/5p expression in SLE CD4+ T cells by modulating histone methylation and acetylation of the miR-142 promoter.

Ding S, Zhang Q, Luo S, Gao L, Huang J, Lu J, Chen J, Zeng Q, Guo A, Zeng J, Lu Q.

Cell Mol Immunol. 2019 Aug 20. doi: 10.1038/s41423-019-0268-3. [Epub ahead of print]


Thymic stromal lymphopoietin epigenetically upregulates Fc receptor γ subunit-related receptors on antigen-presenting cells and induces TH2/TH17 polarization through dectin-2.

Liang Y, Yu B, Chen J, Wu H, Xu Y, Yang B, Lu Q.

J Allergy Clin Immunol. 2019 Jun 25. pii: S0091-6749(19)30822-X. doi: 10.1016/j.jaci.2019.06.011. [Epub ahead of print]


Excessive miR-152-3p Results in Increased BAFF Expression in SLE B-Cells by Inhibiting the KLF5 Expression.

Luo S, Ding S, Liao J, Zhang P, Liu Y, Zhao M, Lu Q.

Front Immunol. 2019 May 22;10:1127. doi: 10.3389/fimmu.2019.01127. eCollection 2019.


T cell receptor β repertoires as novel diagnostic markers for systemic lupus erythematosus and rheumatoid arthritis.

Liu X, Zhang W, Zhao M, Fu L, Liu L, Wu J, Luo S, Wang L, Wang Z, Lin L, Liu Y, Wang S, Yang Y, Luo L, Jiang J, Wang X, Tan Y, Li T, Zhu B, Zhao Y, Gao X, Wan Z, Huang C, Fang M, Li Q, Peng H, Liao X, Chen J, Li F, Ling G, Zhao H, Luo H, Xiang Z, Liao J, Liu Y, Yin H, Long H, Wu H, Yang H, Wang J, Lu Q.

Ann Rheum Dis. 2019 Aug;78(8):1070-1078. doi: 10.1136/annrheumdis-2019-215442. Epub 2019 May 17.


Therapeutic advances in the treatment of SLE.

Mohamed A, Chen Y, Wu H, Liao J, Cheng B, Lu Q.

Int Immunopharmacol. 2019 Jul;72:218-223. doi: 10.1016/j.intimp.2019.03.010. Epub 2019 Apr 16. Review.


Clinical significance and immunobiology of IL-21 in autoimmunity.

Long D, Chen Y, Wu H, Zhao M, Lu Q.

J Autoimmun. 2019 May;99:1-14. doi: 10.1016/j.jaut.2019.01.013. Epub 2019 Feb 14. Review.


Loss of TET proteins in regulatory T cells promotes abnormal proliferation, Foxp3 destabilization and IL-17 expression.

Nakatsukasa H, Oda M, Yin J, Chikuma S, Ito M, Koga-Iizuka M, Someya K, Kitagawa Y, Ohkura N, Sakaguchi S, Koya I, Sanosaka T, Kohyama J, Tsukada YI, Yamanaka S, Takamura-Enya T, Lu Q, Yoshimura A.

Int Immunol. 2019 Apr 26;31(5):335-347. doi: 10.1093/intimm/dxz008.


The Aberrant Epigenetic Modifications in the Pathogenesis of Psoriasis.

Zhao M, Lu Q.

J Investig Dermatol Symp Proc. 2018 Dec;19(2):S81-S82. doi: 10.1016/j.jisp.2018.09.007.


Molecular Control of Follicular Helper T cell Development and Differentiation.

Wu H, Deng Y, Zhao M, Zhang J, Zheng M, Chen G, Li L, He Z, Lu Q.

Front Immunol. 2018 Oct 25;9:2470. doi: 10.3389/fimmu.2018.02470. eCollection 2018. Review.


A rare case report for dermatomyofibroma in nasion.

Fu S, Zhang J, Zhan Y, Zhang H, Herman EI, Lu Q, Zhou Y, Zhang G.

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2018 Sep 28;43(9):1037-1040. doi: 10.11817/j.issn.1672-7347.2018.09.017.


Efficacy, safety, and cost-effectiveness of all-trans retinoic acid/Clobetasol Propionate Compound Ointment in the treatment of mild to moderate psoriasis vulgaris: A randomized, single-blind, multicenter clinical trial.

Xia L, Li R, Wang Y, Lin Z, Zheng J, Li X, Lu Q, Zhang J, Jin H, Fu L, Zhang X, Liu Y, Yang S, Xiao F, Gao XH.

Dermatol Ther. 2018 Sep;31(5):e12632. doi: 10.1111/dth.12632. Epub 2018 Sep 25.


Overexpression of Wilms' tumor 1 in skin lesions of psoriasis is associated with abnormal proliferation and apoptosis of keratinocytes.

Wu R, Liao Y, Shen W, Liu Y, Zhang J, Zheng M, Chen G, Su Y, Zhao M, Lu Q.

Mol Med Rep. 2018 Oct;18(4):3973-3982. doi: 10.3892/mmr.2018.9391. Epub 2018 Aug 16.


The Therapeutic and Pathogenic Role of Autophagy in Autoimmune Diseases.

Yin H, Wu H, Chen Y, Zhang J, Zheng M, Chen G, Li L, Lu Q.

Front Immunol. 2018 Jul 31;9:1512. doi: 10.3389/fimmu.2018.01512. eCollection 2018. Review.


A comprehensive review of immune-mediated dermatopathology in systemic lupus erythematosus.

Li Q, Wu H, Liao W, Zhao M, Chan V, Li L, Zheng M, Chen G, Zhang J, Lau CS, Lu Q.

J Autoimmun. 2018 Sep;93:1-15. doi: 10.1016/j.jaut.2018.07.007. Epub 2018 Jul 11. Review.


Pathogenic role of tissue-resident memory T cells in autoimmune diseases.

Wu H, Liao W, Li Q, Long H, Yin H, Zhao M, Chan V, Lau CS, Lu Q.

Autoimmun Rev. 2018 Sep;17(9):906-911. doi: 10.1016/j.autrev.2018.03.014. Epub 2018 Jul 10. Review.


Crosstalk between metabolism and epigenetic modifications in autoimmune diseases: a comprehensive overview.

Wang Z, Long H, Chang C, Zhao M, Lu Q.

Cell Mol Life Sci. 2018 Sep;75(18):3353-3369. doi: 10.1007/s00018-018-2864-2. Epub 2018 Jul 4. Review.


All-Trans Retinoic Acid Induces CD4+CD25+FOXP3+ Regulatory T Cells by Increasing FOXP3 Demethylation in Systemic Sclerosis CD4+ T Cells.

Sun X, Xiao Y, Zeng Z, Shi Y, Tang B, Long H, Kanekura T, Wang J, Wu H, Zhao M, Lu Q, Xiao R.

J Immunol Res. 2018 Apr 30;2018:8658156. doi: 10.1155/2018/8658156. eCollection 2018.


Elevated histone H3 acetylation is associated with genes involved in T lymphocyte activation and glutamate decarboxylase antibody production in patients with type 1 diabetes.

Wang Y, Hou C, Wisler J, Singh K, Wu C, Xie Z, Lu Q, Zhou Z.

J Diabetes Investig. 2019 Jan;10(1):51-61. doi: 10.1111/jdi.12867. Epub 2018 Jun 26.


Integrative Epigenetic Analysis Reveals Therapeutic Targets to the DNA Methyltransferase Inhibitor Guadecitabine (SGI-110) in Hepatocellular Carcinoma.

Liu M, Zhang L, Li H, Hinoue T, Zhou W, Ohtani H, El-Khoueiry A, Daniels J, O'Connell C, Dorff TB, Lu Q, Weisenberger DJ, Liang G.

Hepatology. 2018 Oct;68(4):1412-1428. doi: 10.1002/hep.30091.


MicroRNA-210 overexpression promotes psoriasis-like inflammation by inducing Th1 and Th17 cell differentiation.

Wu R, Zeng J, Yuan J, Deng X, Huang Y, Chen L, Zhang P, Feng H, Liu Z, Wang Z, Gao X, Wu H, Wang H, Su Y, Zhao M, Lu Q.

J Clin Invest. 2018 Jun 1;128(6):2551-2568. doi: 10.1172/JCI97426. Epub 2018 May 14.

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