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Items: 1 to 20 of 27


Investigation of α-Glucosidase Inhibitory Metabolites from Tetracera scandens Leaves by GC-MS Metabolite Profiling and Docking Studies.

Nokhala A, Siddiqui MJ, Ahmed QU, Ahamad Bustamam MS, Zakaria AZA.

Biomolecules. 2020 Feb 12;10(2). pii: E287. doi: 10.3390/biom10020287.


Toxicity study on Clinacanthus nutans leaf hexane fraction using Danio rerio embryos.

Murugesu S, Khatib A, Ahmed QU, Ibrahim Z, Uzir BF, Benchoula K, Yusoff NIN, Perumal V, Alajmi MF, Salamah S, El-Seedi HR.

Toxicol Rep. 2019 Oct 25;6:1148-1154. doi: 10.1016/j.toxrep.2019.10.020. eCollection 2019.


Synthesis of new isoquinoline-base-oxadiazole derivatives as potent inhibitors of thymidine phosphorylase and molecular docking study.

Zaman K, Rahim F, Taha M, Wadood A, Shah SAA, Ahmed QU, Zakaria ZA.

Sci Rep. 2019 Nov 5;9(1):16015. doi: 10.1038/s41598-019-52100-0.


Identification of α-glucosidase inhibitors from Clinacanthus nutans leaf extract using liquid chromatography-mass spectrometry-based metabolomics and protein-ligand interaction with molecular docking.

Murugesu S, Ibrahim Z, Ahmed QU, Uzir BF, Nik Yusoff NI, Perumal V, Abas F, Shaari K, Khatib A.

J Pharm Anal. 2019 Apr;9(2):91-99. doi: 10.1016/j.jpha.2018.11.001. Epub 2018 Nov 15.


Synthesis of Chromen-4-One-Oxadiazole Substituted Analogs as Potent β-Glucuronidase Inhibitors.

Taha M, Rahim F, Ali M, Khan MN, Alqahtani MA, Bamarouf YA, Gollapalli M, Farooq RK, Shah SAA, Ahmed QU, Zakaria ZA.

Molecules. 2019 Apr 18;24(8). pii: E1528. doi: 10.3390/molecules24081528.


Optimization of Hyperglycemic Induction in Zebrafish and Evaluation of Its Blood Glucose Level and Metabolite Fingerprint Treated with Psychotria malayana Jack Leaf Extract.

Benchoula K, Khatib A, Quzwain FMC, Che Mohamad CA, Wan Sulaiman WMA, Abdul Wahab R, Ahmed QU, Abdul Ghaffar M, Saiman MZ, Alajmi MF, El-Seedi H.

Molecules. 2019 Apr 17;24(8). pii: E1506. doi: 10.3390/molecules24081506.


Anticancer activity of grassy Hystrix brachyura bezoar and its mechanisms of action: An in vitro and in vivo based study.

Khan AYF, Ahmed QU, Narayanamurthy V, Razali S, Asuhaimi FA, Saleh MSM, Johan MF, Khatib A, Seeni A, Wahab RA.

Biomed Pharmacother. 2019 Jun;114:108841. doi: 10.1016/j.biopha.2019.108841. Epub 2019 Apr 10.


Antinociceptive activity of petroleum ether fraction obtained from methanolic extract of Clinacanthus nutans leaves involves the activation of opioid receptors and NO-mediated/cGMP-independent pathway.

Zakaria ZA, Abdul Rahim MH, Mohd Sani MH, Omar MH, Ching SM, Abdul Kadir A, Ahmed QU.

BMC Complement Altern Med. 2019 Apr 2;19(1):79. doi: 10.1186/s12906-019-2486-8.


Evaluation of the Enzyme Inhibitory and Antioxidant Activities of Entada spiralis Stem Bark and Isolation of the Active Constituents.

Roheem FO, Mat Soad SZ, Ahmed QU, Ali Shah SA, Latip J, Zakaria ZA.

Molecules. 2019 Mar 13;24(6). pii: E1006. doi: 10.3390/molecules24061006.


Synthesis of Thymidine Phosphorylase Inhibitor Based on Quinoxaline Derivatives and Their Molecular Docking Study.

Almandil NB, Taha M, Farooq RK, Alhibshi A, Ibrahim M, Anouar EH, Gollapalli M, Rahim F, Nawaz M, Shah SAA, Ahmed QU, Zakaria ZA.

Molecules. 2019 Mar 13;24(6). pii: E1002. doi: 10.3390/molecules24061002.


Hystrix brachyura Bezoar Characterization, Antioxidant Activity Screening, and Anticancer Activity on Melanoma Cells (A375): A Preliminary Study.

Firus Khan AY, Abdullah Asuhaimi F, Jalal TK, Roheem FO, Natto HA, Johan MF, Ahmed QU, Abdul Wahab R.

Antioxidants (Basel). 2019 Feb 12;8(2). pii: E39. doi: 10.3390/antiox8020039.


Isolation and characterization of novel antibacterial compound from an untapped plant, Stereospermum fimbriatum.

Izyani Awang AF, Ahmed QU, Shah SAA, Jaffri JM, Ghafoor K, Uddin ABMH, Ferdosh S, Islam Sarker MZ.

Nat Prod Res. 2020 Mar;34(5):629-637. doi: 10.1080/14786419.2018.1494170. Epub 2018 Nov 23.


Methylation and Acetylation Enhanced the Antidiabetic Activity of Some Selected Flavonoids: In Vitro, Molecular Modelling and Structure Activity Relationship-Based Study.

Ahmed QU, Sarian MN, Mat So'ad SZ, Latip J, Arief Ichwan SJ, Hussein NN, Taher M, Alhassan AM, Hamidon H, Fakurazi S.

Biomolecules. 2018 Nov 15;8(4). pii: E149. doi: 10.3390/biom8040149.


Antiradical and Xanthine Oxidase Inhibitory Activity Evaluations of Averrhoa bilimbi L. Leaves and Tentative Identification of Bioactive Constituents through LC-QTOF-MS/MS and Molecular Docking Approach.

Ahmed QU, Alhassan AM, Khatib A, Shah SAA, Hasan MM, Sarian MN.

Antioxidants (Basel). 2018 Oct 8;7(10). pii: E137. doi: 10.3390/antiox7100137.


Characterization of α-Glucosidase Inhibitors from Clinacanthus nutans Lindau Leaves by Gas Chromatography-Mass Spectrometry-Based Metabolomics and Molecular Docking Simulation.

Murugesu S, Ibrahim Z, Ahmed QU, Nik Yusoff NI, Uzir BF, Perumal V, Abas F, Saari K, El-Seedi H, Khatib A.

Molecules. 2018 Sep 19;23(9). pii: E2402. doi: 10.3390/molecules23092402.


A simple method for extracting both active oily and water soluble extract (WSE) from Nigella sativa (L.) seeds using a single solvent system.

Babar ZM, Azizi WM, Ichwan SJ, Ahmed QU, Azad AK, Mawa I.

Nat Prod Res. 2019 Aug;33(15):2266-2270. doi: 10.1080/14786419.2018.1493587. Epub 2018 Jul 24.


Animal models and natural products to investigate in vivo and in vitro antidiabetic activity.

Hasan MM, Ahmed QU, Mat Soad SZ, Tunna TS.

Biomed Pharmacother. 2018 May;101:833-841. doi: 10.1016/j.biopha.2018.02.137. Epub 2018 Mar 22. Review.


A new sulphated flavone and other phytoconstituents from the leaves of Tetracera indica Merr. and their alpha-glucosidase inhibitory activity.

Alhassan AM, Ahmed QU, Latip J, Shah SAA.

Nat Prod Res. 2019 Jan;33(1):1-8. doi: 10.1080/14786419.2018.1437427. Epub 2018 Feb 8.


Antioxidant and Antidiabetic Effects of Flavonoids: A Structure-Activity Relationship Based Study.

Sarian MN, Ahmed QU, Mat So'ad SZ, Alhassan AM, Murugesu S, Perumal V, Syed Mohamad SNA, Khatib A, Latip J.

Biomed Res Int. 2017;2017:8386065. doi: 10.1155/2017/8386065. Epub 2017 Nov 28.


Flavonoids from Tetracera indica Merr. induce adipogenesis and exert glucose uptake activities in 3T3-L1 adipocyte cells.

Hasan MM, Ahmed QU, Soad SZM, Latip J, Taher M, Syafiq TMF, Sarian MN, Alhassan AM, Zakaria ZA.

BMC Complement Altern Med. 2017 Aug 30;17(1):431. doi: 10.1186/s12906-017-1929-3.

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