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Items: 1 to 20 of 39

1.

Claudin-1, A Double-Edged Sword in Cancer.

Bhat AA, Syed N, Therachiyil L, Nisar S, Hashem S, Macha MA, Yadav SK, Krishnankutty R, Muralitharan S, Al-Naemi H, Bagga P, Reddy R, Dhawan P, Akobeng A, Uddin S, Frenneaux MP, El-Rifai W, Haris M.

Int J Mol Sci. 2020 Jan 15;21(2). pii: E569. doi: 10.3390/ijms21020569. Review.

2.

Curcumin use in ulcerative colitis: is it ready for prime time? A systematic review and meta-analysis of clinical trials.

Chandan S, Mohan BP, Chandan OC, Ahmad R, Challa A, Tummala H, Singh S, Dhawan P, Ponnada S, Singh AB, Adler DG.

Ann Gastroenterol. 2020 Jan-Feb;33(1):53-58. doi: 10.20524/aog.2019.0439. Epub 2019 Nov 29.

3.

Role of Claudin Proteins in Regulating Cancer Stem Cells and Chemoresistance-Potential Implication in Disease Prognosis and Therapy.

Gowrikumar S, Singh AB, Dhawan P.

Int J Mol Sci. 2019 Dec 20;21(1). pii: E53. doi: 10.3390/ijms21010053. Review.

4.

Cocaine Induces Inflammatory Gut Milieu by Compromising the Mucosal Barrier Integrity and Altering the Gut Microbiota Colonization.

Chivero ET, Ahmad R, Thangaraj A, Periyasamy P, Kumar B, Kroeger E, Feng D, Guo ML, Roy S, Dhawan P, Singh AB, Buch S.

Sci Rep. 2019 Aug 21;9(1):12187. doi: 10.1038/s41598-019-48428-2.

5.

Correction: Upregulated claudin-1 expression promotes colitis-associated cancer by promoting β-catenin phosphorylation and activation in Notch/p-AKT-dependent manner.

Gowrikumar S, Ahmad R, Uppada SB, Washington MK, Shi C, Singh AB, Dhawan P.

Oncogene. 2019 Sep;38(38):6566. doi: 10.1038/s41388-019-0864-9.

PMID:
31417178
6.

Anti-Claudin-1 Conjugated to a Near-Infrared Fluorophore Targets Colon Cancer in PDOX Mouse Models.

Hollandsworth HM, Lwin TM, Amirfakhri S, Filemoni F, Batra SK, Hoffman RM, Dhawan P, Bouvet M.

J Surg Res. 2019 Oct;242:145-150. doi: 10.1016/j.jss.2019.04.048. Epub 2019 May 9.

PMID:
31077946
7.

Upregulated claudin-1 expression promotes colitis-associated cancer by promoting β-catenin phosphorylation and activation in Notch/p-AKT-dependent manner.

Gowrikumar S, Ahmad R, Uppada SB, Washington MK, Shi C, Singh AB, Dhawan P.

Oncogene. 2019 Jun;38(26):5321-5337. doi: 10.1038/s41388-019-0795-5. Epub 2019 Apr 10. Erratum in: Oncogene. 2019 Sep;38(38):6566.

8.

SMAD4 Loss in Colorectal Cancer Patients Correlates with Recurrence, Loss of Immune Infiltrate, and Chemoresistance.

Wasserman I, Lee LH, Ogino S, Marco MR, Wu C, Chen X, Datta J, Sadot E, Szeglin B, Guillem JG, Paty PB, Weiser MR, Nash GM, Saltz L, Barlas A, Manova-Todorova K, Uppada SPB, Elghouayel AE, Ntiamoah P, Glickman JN, Hamada T, Kosumi K, Inamura K, Chan AT, Nishihara R, Cercek A, Ganesh K, Kemeny NE, Dhawan P, Yaeger R, Sawyers CL, Garcia-Aguilar J, Giannakis M, Shia J, Smith JJ.

Clin Cancer Res. 2019 Mar 15;25(6):1948-1956. doi: 10.1158/1078-0432.CCR-18-1726. Epub 2018 Dec 26.

PMID:
30587545
9.

Tight junction proteins in gastrointestinal and liver disease.

Zeisel MB, Dhawan P, Baumert TF.

Gut. 2018 Oct 8. pii: gutjnl-2018-316906. doi: 10.1136/gutjnl-2018-316906. [Epub ahead of print] Review.

10.

MASTL induces Colon Cancer progression and Chemoresistance by promoting Wnt/β-catenin signaling.

Uppada SB, Gowrikumar S, Ahmad R, Kumar B, Szeglin B, Chen X, Smith JJ, Batra SK, Singh AB, Dhawan P.

Mol Cancer. 2018 Aug 1;17(1):111. doi: 10.1186/s12943-018-0848-3.

11.

HDAC-4 regulates claudin-2 expression in EGFR-ERK1/2 dependent manner to regulate colonic epithelial cell differentiation.

Ahmad R, Kumar B, Pan K, Dhawan P, Singh AB.

Oncotarget. 2017 Sep 23;8(50):87718-87736. doi: 10.18632/oncotarget.21190. eCollection 2017 Oct 20.

12.

Obesity-induces Organ and Tissue Specific Tight Junction Restructuring and Barrier Deregulation by Claudin Switching.

Ahmad R, Rah B, Bastola D, Dhawan P, Singh AB.

Sci Rep. 2017 Jul 11;7(1):5125. doi: 10.1038/s41598-017-04989-8.

13.

Claudin proteins, outside-in signaling, and carcinogenesis.

Singh AB, Uppada SB, Dhawan P.

Pflugers Arch. 2017 Jan;469(1):69-75. doi: 10.1007/s00424-016-1919-1. Epub 2016 Dec 17. Review.

14.

Claudin-1 promotes TNF-α-induced epithelial-mesenchymal transition and migration in colorectal adenocarcinoma cells.

Bhat AA, Ahmad R, Uppada SB, Singh AB, Dhawan P.

Exp Cell Res. 2016 Nov 15;349(1):119-127. doi: 10.1016/j.yexcr.2016.10.005. Epub 2016 Oct 11.

15.

MUC4 is negatively regulated through the Wnt/β-catenin pathway via the Notch effector Hath1 in colorectal cancer.

Pai P, Rachagani S, Dhawan P, Sheinin YM, Macha MA, Qazi AK, Chugh S, Ponnusamy MP, Mallya K, Pothuraju R, Batra SK.

Genes Cancer. 2016 May;7(5-6):154-168. doi: 10.18632/genesandcancer.108.

16.

Mucins and Wnt/β-catenin signaling in gastrointestinal cancers: an unholy nexus.

Pai P, Rachagani S, Dhawan P, Batra SK.

Carcinogenesis. 2016 Mar;37(3):223-32. doi: 10.1093/carcin/bgw005. Epub 2016 Jan 13. Review.

17.

Cancer Stem Cell and Gastrointestinal Cancer: Current Status, Targeted Therapy and Future Implications.

Ahmad R, Dhawan P, Singh AB.

Biochem Pharmacol (Los Angel). 2016;5(2). pii: 202. doi: 10.4172/2167-0501.1000202. Epub 2016 Feb 26.

18.

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

Block KI, Gyllenhaal C, Lowe L, Amedei A, Amin ARMR, Amin A, Aquilano K, Arbiser J, Arreola A, Arzumanyan A, Ashraf SS, Azmi AS, Benencia F, Bhakta D, Bilsland A, Bishayee A, Blain SW, Block PB, Boosani CS, Carey TE, Carnero A, Carotenuto M, Casey SC, Chakrabarti M, Chaturvedi R, Chen GZ, Chen H, Chen S, Chen YC, Choi BK, Ciriolo MR, Coley HM, Collins AR, Connell M, Crawford S, Curran CS, Dabrosin C, Damia G, Dasgupta S, DeBerardinis RJ, Decker WK, Dhawan P, Diehl AME, Dong JT, Dou QP, Drew JE, Elkord E, El-Rayes B, Feitelson MA, Felsher DW, Ferguson LR, Fimognari C, Firestone GL, Frezza C, Fujii H, Fuster MM, Generali D, Georgakilas AG, Gieseler F, Gilbertson M, Green MF, Grue B, Guha G, Halicka D, Helferich WG, Heneberg P, Hentosh P, Hirschey MD, Hofseth LJ, Holcombe RF, Honoki K, Hsu HY, Huang GS, Jensen LD, Jiang WG, Jones LW, Karpowicz PA, Keith WN, Kerkar SP, Khan GN, Khatami M, Ko YH, Kucuk O, Kulathinal RJ, Kumar NB, Kwon BS, Le A, Lea MA, Lee HY, Lichtor T, Lin LT, Locasale JW, Lokeshwar BL, Longo VD, Lyssiotis CA, MacKenzie KL, Malhotra M, Marino M, Martinez-Chantar ML, Matheu A, Maxwell C, McDonnell E, Meeker AK, Mehrmohamadi M, Mehta K, Michelotti GA, Mohammad RM, Mohammed SI, Morre DJ, Muralidhar V, Muqbil I, Murphy MP, Nagaraju GP, Nahta R, Niccolai E, Nowsheen S, Panis C, Pantano F, Parslow VR, Pawelec G, Pedersen PL, Poore B, Poudyal D, Prakash S, Prince M, Raffaghello L, Rathmell JC, Rathmell WK, Ray SK, Reichrath J, Rezazadeh S, Ribatti D, Ricciardiello L, Robey RB, Rodier F, Rupasinghe HPV, Russo GL, Ryan EP, Samadi AK, Sanchez-Garcia I, Sanders AJ, Santini D, Sarkar M, Sasada T, Saxena NK, Shackelford RE, Shantha Kumara HMC, Sharma D, Shin DM, Sidransky D, Siegelin MD, Signori E, Singh N, Sivanand S, Sliva D, Smythe C, Spagnuolo C, Stafforini DM, Stagg J, Subbarayan PR, Sundin T, Talib WH, Thompson SK, Tran PT, Ungefroren H, Vander Heiden MG, Venkateswaran V, Vinay DS, Vlachostergios PJ, Wang Z, Wellen KE, Whelan RL, Yang ES, Yang H, Yang X, Yaswen P, Yedjou C, Yin X, Zhu J, Zollo M.

Semin Cancer Biol. 2015 Dec;35 Suppl:S276-S304. doi: 10.1016/j.semcancer.2015.09.007. Review.

19.

Claudins and cancer: Fall of the soldiers entrusted to protect the gate and keep the barrier intact.

Singh AB, Dhawan P.

Semin Cell Dev Biol. 2015 Jun;42:58-65. doi: 10.1016/j.semcdb.2015.05.001. Epub 2015 May 27. Review.

PMID:
26025580
20.

Claudin-1 overexpression in intestinal epithelial cells enhances susceptibility to adenamatous polyposis coli-mediated colon tumorigenesis.

Pope JL, Ahmad R, Bhat AA, Washington MK, Singh AB, Dhawan P.

Mol Cancer. 2014 Jul 6;13:167. doi: 10.1186/1476-4598-13-167.

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